Detailed information of TA system TA234028

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): IasE-IsrA/-
• Location: 3541054..3541446
• Replicon: chromosome
• Accession: NZ_CP091615
• Organism: Salmonella enterica strain 1653

Toxin (Protein)

• Gene name: IasE
• Uniprot ID: -
• Locus tag: L5511_RS17145
• Protein ID: WP_241467015.1
• Coordinates: 3541201..3541446 (+)
• Length: 82 a.a.

Antitoxin (RNA)

Gene name	IsrA
Locus tag	-
Coordinates	3541054..3541410 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L5511_RS17115	3536306..3536803	-	498	WP_165963407.1	pilus assembly protein	-
L5511_RS17120	3537565..3538269	-	705	Protein_3351	integrase core domain-containing protein	-
L5511_RS17125	3538322..3538636	+	315	WP_133322996.1	SymE family type I addiction module toxin	-
L5511_RS17130	3538703..3538981	-	279	WP_133323248.1	hypothetical protein	-
L5511_RS17135	3539299..3539766	-	468	WP_000828178.1	sugar tyrosine-protein kinase	-
L5511_RS17140	3540584..3541003	-	420	WP_131040133.1	hypothetical protein	-
-	3541054..3541410	-	357	-	-	Antitoxin
L5511_RS17145	3541201..3541446	+	246	WP_241467015.1	hypothetical protein	Toxin
L5511_RS17150	3541513..3542055	-	543	WP_079984650.1	hypothetical protein	-
L5511_RS17155	3542055..3546161	-	4107	WP_133322998.1	RHS repeat-associated core domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3528401..3542055	13654

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 82 a.a.
• Molecular weight: 8848.00 Da
• Isoelectric Point: 4.0543

>T234028 WP_241467015.1 NZ_CP091615:3541201-3541446 [Salmonella enterica]
MNASDVSVRHINSETCMTACYSQIPSGDCQEEAGFETGRSVTVKISDGCIVLMADGNEVQKLCEQLYQAEQVVKGMWDVI
V

Nucleotide

• Length: 246 bp

>T234028 NZ_LR025088:4283847-4284131 [Klebsiella pneumoniae]
ATGACCTATGAACTGGAGTTTGATCCACGAGCCTGGCGCGAATGGCAGAAGCCTGGCGAGACGGTCAAAAAACAGTTCAA
AAATAAGCTCCAGCAGATTGTGCAGAATCCGCGAATTGAGTCGGCCAGGCTGAGCGATTTACCGGATTGCTACAAAATCA
AGCTTAAGGCGTCAGGTTATCGGTTGGTGTATCAAGTACGAGATAGTGTGGTGGTGGTTTACGTTATTGCCATTGGCAAA
AGAGAGAAAGCGGCCGTTTATCATCAGGCGAATAAACGGCTCTAA

Antitoxin

Nucleotide

• Length: 357 bp

>AT234028 NZ_CP091615:c3541410-3541054 [Salmonella enterica]
TTCAGCCTGATAAAGCTGTTCGCACAGCTTCTGCACCTCGTTACCGTCCGCCATTAGCACAATACACCCGTCCGAAATCT
TCACCGTCACGCTGCGCCCGGTCTCAAATCCCGCTTCTTCCTGGCAGTCGCCGCTGGGGATTTGTGAGTAACAGGCGGTC
ATGCAGGTTTCGCTGTTGATGTGGCGGACGCTGACGTCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTAATTCTC
CGCCGGATGCTGGCTGATTGTGGAGCTCAGGGTGAGCGAGTATGGGCGCGACATCCTGGCATCGCGCCTCTCTCTCCCCG
GCCAGTGATGAGCAACCGGCTGCCGGGGCCGTATTTT

Structures

Antitoxin