Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) fst-RNAII/-
Location 349462..349656 Replicon chromosome
Accession NZ_CP091231
Organism Enterococcus faecalis strain 732

Toxin (Protein)


Gene name fst Uniprot ID -
Locus tag LQ055_RS01840 Protein ID WP_142954371.1
Coordinates 349561..349656 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name RNAII
Locus tag -
Coordinates 349462..349526 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ055_RS01825 345086..346834 + 1749 WP_002403688.1 PTS transporter subunit EIIC -
LQ055_RS01830 346825..348858 + 2034 WP_002355275.1 BglG family transcription antiterminator -
LQ055_RS01835 348869..349303 + 435 WP_002355276.1 PTS sugar transporter subunit IIA -
- 349462..349526 + 65 - - Antitoxin
LQ055_RS01840 349561..349656 - 96 WP_142954371.1 type I toxin-antitoxin system Fst family toxin Toxin
LQ055_RS01845 349902..351674 + 1773 WP_002387897.1 PTS mannitol-specific transporter subunit IIBC -
LQ055_RS01850 351689..352126 + 438 WP_002355279.1 PTS sugar transporter subunit IIA -
LQ055_RS01855 352141..353295 + 1155 WP_002355280.1 mannitol-1-phosphate 5-dehydrogenase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
flank IS/Tn - - 353424..354227 803


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-38)


Sequences


Toxin        


Download         Length: 32 a.a.        Molecular weight: 3645.44 Da        Isoelectric Point: 4.6275

>T232956 WP_142954371.1 NZ_CP091231:c349656-349561 [Enterococcus faecalis]
MYEIVTKVLVPIFVGIVLKLVTIWLEKQNEE

Download         Length: 96 bp

>T232956 NZ_CP128501:c1624459-1624343 [Bacillus amyloliquefaciens]
ATGACTGTTTACGAATCATTAATGATAATGATCAATTTTGGCGGATTGATATTAAATACCGTCTTGTTGATCTTCAATAT
AATGATGATTGTAACGTCAAGCCAAAAGAAAAAATAG

Antitoxin


Download         Length: 65 bp

>AT232956 NZ_CP091231:349462-349526 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGCGGTAGGGTGTCTTTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References