Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) bsrE-as-bsrE/-
Location 2074484..2074730 Replicon chromosome
Accession NZ_CP089592
Organism Bacillus subtilis strain Bsi

Toxin (Protein)


Gene name bsrE Uniprot ID -
Locus tag LUV29_RS10370 Protein ID WP_109789044.1
Coordinates 2074484..2074576 (+) Length 31 a.a.

Antitoxin (RNA)


Gene name as-bsrE
Locus tag -
Coordinates 2074557..2074730 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LUV29_RS10355 2069643..2069978 + 336 WP_009967409.1 hypothetical protein -
LUV29_RS10360 2070025..2073630 - 3606 WP_004399367.1 P-loop NTPase fold protein -
LUV29_RS10365 2073863..2074195 - 333 WP_026009814.1 hypothetical protein -
LUV29_RS10370 2074484..2074576 + 93 WP_109789044.1 type I toxin-antitoxin system toxin BsrE Toxin
- 2074557..2074730 - 174 - - Antitoxin
LUV29_RS10375 2074845..2075687 - 843 WP_003231327.1 hypothetical protein -
LUV29_RS10380 2075887..2076345 - 459 WP_003231326.1 type VII secretion system immunity protein YobK -
LUV29_RS10385 2076355..2078157 - 1803 WP_004399481.1 LXG family T7SS effector ribonuclease toxin YobL -
LUV29_RS10390 2078259..2078816 - 558 WP_004399321.1 SMI1/KNR4 family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2060879..2121271 60392


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-24)


Sequences


Toxin        


Download         Length: 31 a.a.        Molecular weight: 3358.16 Da        Isoelectric Point: 4.1840

>T228391 WP_109789044.1 NZ_CP089592:2074484-2074576 [Bacillus subtilis]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Download         Length: 93 bp

>T228391 NZ_CP123897:c5154637-5154512 [Methylomonas sp. UP202]
ATGACCACCCATGCAGACCATAAGGTTTGGCAGGATATTTACCGGCCCAAGACCTTGGTCGGCGATGTTTATCTGAAATT
GACTGTCATTGATGATGTGTTGGTCGTTTCGTTTAAGGAGTTGTGA

Antitoxin


Download         Length: 174 bp

>AT228391 NZ_CP089592:c2074730-2074557 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References