Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1929867..1930049 Replicon chromosome
Accession NC_010079
Organism Staphylococcus aureus subsp. aureus USA300 TCH1516

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag USA300HOU_RS15780 Protein ID WP_001801861.1
Coordinates 1929867..1929962 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1929990..1930049 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
USA300HOU_RS09550 1925527..1926153 + 627 Protein_1843 hypothetical protein -
USA300HOU_RS09555 1926194..1926538 + 345 WP_000627551.1 DUF3969 family protein -
USA300HOU_RS09560 1926636..1927187 + 552 WP_000414205.1 hypothetical protein -
USA300HOU_RS09565 1927405..1928046 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
USA300HOU_RS09570 1928160..1928345 - 186 WP_000809857.1 hypothetical protein -
USA300HOU_RS09575 1928347..1928523 - 177 WP_000375476.1 hypothetical protein -
USA300HOU_RS09580 1928534..1928917 - 384 WP_000070811.1 hypothetical protein -
USA300HOU_RS09590 1929521..1929664 - 144 WP_001549059.1 transposase -
USA300HOU_RS15780 1929867..1929962 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1929990..1930049 - 60 - - Antitoxin
USA300HOU_RS09595 1930085..1930186 + 102 WP_001791893.1 hypothetical protein -
USA300HOU_RS15375 1930164..1930340 - 177 Protein_1853 transposase -
USA300HOU_RS09600 1930534..1930911 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA 1922967..1963137 40170


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T22542 WP_001801861.1 NC_010079:1929867-1929962 [Staphylococcus aureus subsp. aureus USA300_TCH1516]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T22542 NC_010079:1929867-1929962 [Staphylococcus aureus subsp. aureus USA300_TCH1516]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT22542 NC_010079:c1930049-1929990 [Staphylococcus aureus subsp. aureus USA300_TCH1516]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References