Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1887596..1887830 Replicon chromosome
Accession NC_008258
Organism Shigella flexneri 5 str. 8401

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1887597..1887700 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1887596..1887830 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SFV_RS28545 1882730..1883152 + 423 WP_001249968.1 hypothetical protein -
SFV_RS10255 1883130..1883402 + 273 WP_001277358.1 host-nuclease inhibitor protein Gam -
SFV_RS10260 1883432..1884529 + 1098 WP_001173296.1 AAA family ATPase -
SFV_RS10265 1884580..1884768 + 189 WP_000276807.1 DUF1187 family protein -
- 1884586..1884764 - 179 NuclAT_0 - -
- 1884586..1884764 - 179 NuclAT_0 - -
- 1884586..1884764 - 179 NuclAT_0 - -
- 1884586..1884764 - 179 NuclAT_0 - -
SFV_RS10275 1884869..1886025 + 1157 WP_094081558.1 IS3 family transposase -
SFV_RS25640 1886142..1886423 + 282 WP_094096572.1 excisionase -
SFV_RS10280 1886389..1887465 + 1077 WP_001189100.1 phage integrase Arm DNA-binding domain-containing protein -
- 1887596..1887830 + 235 - - Antitoxin
- 1887597..1887700 - 104 - - Toxin
SFV_RS10290 1887858..1888199 - 342 WP_000976476.1 YebY family protein -
SFV_RS10295 1888212..1889084 - 873 WP_000879271.1 copper homeostasis membrane protein CopD -
SFV_RS10300 1889088..1889462 - 375 WP_000168747.1 CopC domain-containing protein YobA -
SFV_RS10305 1889601..1889831 + 231 WP_000916757.1 DNA polymerase III subunit theta -
SFV_RS10310 1889933..1890589 + 657 Protein_1896 carbon-nitrogen hydrolase family protein -
SFV_RS10315 1890613..1891275 + 663 WP_000944267.1 exodeoxyribonuclease X -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 1876166..1893332 17166


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences

Toxin        


Download         Length: 104 bp

>T21654 NC_008258:c1887700-1887597 [Shigella flexneri 5 str. 8401]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT21654 NC_008258:1887596-1887830 [Shigella flexneri 5 str. 8401]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures

Antitoxin

Download structure file

Antitoxin

Download structure file

References