Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 2413232..2413414 Replicon chromosome
Accession NZ_CP079715
Organism Staphylococcus aureus strain V8

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag KX797_RS11925 Protein ID WP_001801861.1
Coordinates 2413232..2413327 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2413355..2413414 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KX797_RS11885 2408892..2409518 + 627 WP_000669046.1 hypothetical protein -
KX797_RS11890 2409559..2409903 + 345 WP_000627551.1 DUF3969 family protein -
KX797_RS11895 2410001..2410552 + 552 WP_000414205.1 hypothetical protein -
KX797_RS11900 2410770..2411411 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
KX797_RS11905 2411525..2411710 - 186 WP_000809857.1 hypothetical protein -
KX797_RS11910 2411712..2411888 - 177 WP_000375476.1 hypothetical protein -
KX797_RS11915 2411899..2412282 - 384 WP_000070811.1 hypothetical protein -
KX797_RS11920 2412886..2413029 - 144 WP_001549059.1 transposase -
KX797_RS11925 2413232..2413327 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 2413355..2413414 - 60 - - Antitoxin
KX797_RS11930 2413450..2413551 + 102 WP_001791893.1 hypothetical protein -
KX797_RS11935 2413529..2413705 - 177 Protein_2358 transposase -
KX797_RS11940 2413899..2414276 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA 2406332..2446494 40162


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T209764 WP_001801861.1 NZ_CP079715:2413232-2413327 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T209764 NZ_CP104302:1821901-1822281 [Mycolicibacterium brumae]
GTGAGGCTGGTCGACTCGGACGTCCTCATCGCTCACCTGCGTGGCGTGGCGCCGGCGCGTGACTGGCTGCTGGCTGCCCG
AGCGGAGGGCCCGTTGGCGATCAGTGTGGTGTCCATAACCGAGTTGATCGGCGGGATGGTTAGTGCGGAGCGCCGGGAAG
TGTGGCGGCTGCTCGCCACATTTCGCGCTGAGCCGGTCACTGAGATCATCGCGCGTCGAGCGGGCGACTTCATGCGGGAG
TACCGGCGCAGTCATACCGGTATCGGTTTGGGCGACTACCTGATCGCCGCCACGGCCGATATCAACGGCTATGAGCCGGC
GACGTTCAACGTCAGACACTTCCCGATGTTCAAGAATCTGCGTCCGCCGTTTGAGTTCTGA

Antitoxin


Download         Length: 60 bp

>AT209764 NZ_CP079715:c2413414-2413355 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References