Detailed information of TA system TA207415

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): IasE-IsrA/SymE(toxin)
• Location: 3577067..3577318
• Replicon: chromosome
• Accession: NZ_CP077670
• Organism: Salmonella enterica strain S90

Toxin (Protein)

• Gene name: IasE
• Uniprot ID: -
• Locus tag: KTP13_RS17545
• Protein ID: WP_131166435.1
• Coordinates: 3577067..3577318 (+)
• Length: 84 a.a.

Antitoxin (RNA)

Gene name	IsrA
Locus tag	-
Coordinates	3577083..3577308 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KTP13_RS17525	3573595..3574335	-	741	WP_051129375.1	pili assembly chaperone SafB	-
KTP13_RS17530	3574410..3574907	-	498	WP_051129374.1	Saf-pilin pilus formation protein SafA	-
KTP13_RS17535	3575040..3575534	-	495	WP_051129373.1	hypothetical protein	-
KTP13_RS17540	3576302..3577003	-	702	Protein_3429	integrase core domain-containing protein	-
KTP13_RS17545	3577067..3577318	+	252	WP_131166435.1	SymE family type I addiction module toxin	Toxin
-	3577083..3577308	-	226	-	-	Antitoxin
KTP13_RS17550	3577364..3577828	-	465	WP_127201574.1	hypothetical protein	-
KTP13_RS17555	3578209..3579054	-	846	Protein_3432	RHS domain-containing protein	-
KTP13_RS17560	3579074..3579211	+	138	WP_023227287.1	hypothetical protein	-
KTP13_RS17565	3579354..3579962	-	609	WP_053505599.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3557199..3601514	44315
	-	flank	IS/Tn	-	-	3576302..3576580	278

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin SymE-like (10-48)

Sequences

Toxin

Protein

• Length: 84 a.a.
• Molecular weight: 9451.82 Da
• Isoelectric Point: 8.0365

>T207415 WP_131166435.1 NZ_CP077670:3577067-3577318 [Salmonella enterica]
MRDTYKTHMTTYYSRIPSLHLKGDWLAEAGFDTGASVTVKISEGCLTLIVETDEVRDLRRELYQVKKSMKHIKAGVYDVV
NGN

Nucleotide

• Length: 252 bp

>T207415 NZ_CP102987:c2592328-2591006 [Klebsiella pneumoniae]
ATGGCGACGCTTACCACCTGGATGAACAATGTGCGCGTGGGAACCTTAACCCGCCAGGCTAACGGGGCGCACAGTTTTCG
CTATGACGAAGAGTGGCTGCGCAGCCCGCGCGCCAGACCGCTCTCCCTCTCACTGCCGCTGCAGTATGGCAATATCACTG
CCGACGCGGTGTATCACTATTTTGATAACCTGCTGCCCGACAGCCCGCAGGTCCGCGACCGGATCGTCAGGCGCTATCAG
GCGCGCTCGAAGCAGCCGTTCGATCTGCTGGCCGAAGTCGGGCGGGATAGCGTAGGGGCGGTGACCCTCCTGCCGCCGGG
GGAAGAGGCGCACCTGGAAGGATTACGCTGGCAGACGCTGGACGAGGCGCAGCTCACCGCTTTGCTGACCGCTTACCAGT
CGGATATCCCCCTCGGGATGATTACCAGCCAGGACGATTTCCGTATCTCGGTGGCCGGCGCCCAGGAGAAAACGGCGCTG
CTGCGGATGGGCGAGCAGTGGTGTATTCCGCAGGGCGCCACGCCGACCACGCATATCATTAAGCTGCCCATCGGCGAGAT
CAAGCAGCCCAATGCGACGCTGGATCTGCGTGAAAGCGTGGATAATGAGTATCTGTGCCTGGCGCTGGCCAGAGAACTGG
GCCTGGCGGTGCCGGAAGCGGAGATCATCACCACCCCGCGGATCCGCGCCCTGGCGGTAACCCGCTTCGACCGGCGCTGG
GCGCAGGAGGGACGGGTGCTGCTGCGTCTGCCGCAGGAGGATCTGTGTCAGGCTTTTGGTCTTCCTTCAGCGATGAAATA
TGAGTCTGACGGCGGGCCGGGTATCGCCGCGATCATGACCTTTCTGCTGGGCTCGAGTGAAGCGCTGAAAGATCGCTATG
ACTTTATGAAGTTCATGGTCTTCCAGTGGCTGACGGGGGCGACGGACGGTCACGCAAAAAACTTCTCAATTTACCTGTTG
CCCGGCGGCAGCTACCGCTTAACACCGTTCTACGACATTATTTCGGCGTTTCCGGTGCTGGGCGGCACGGGACTGCATCT
GCGCGATCTGAAGCTGTCGATGGGGCTCAATGCCACAAAAGGGCGTAAAACAGAGATTAACGCCATCTATCCGCGTCATT
TTCTGGCGACGGCCAAAGCGGTGAACTTTCCCCGGGAGCAGATGCTGGCGATCCTCCAGGAGTTTGCCGGGCATGTGCCG
CAGGCAATCGAAAGCGCTCGCCGGACGCTGCCGGCGGACTTTTCCAGCCACGTCTGGCAGGCCATTACAGAGAACATGCT
GAAGCTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGCTATAG

Antitoxin

Nucleotide

• Length: 226 bp

>AT207415 NZ_CP077670:c3577308-3577083 [Salmonella enterica]
TTCACCACATCATATACCCCCGCCTTAATGTGCTTCATCGACTTTTTCACCTGATAAAGCTCCCTCCGTAGATCCCTCAC
TTCGTCTGTCTCCACAATCAGAGTCAAACACCCTTCGGAGATCTTCACGGTCACGCTCGCCCCGGTATCAAATCCCGCTT
CTGCCAGCCAGTCGCCCTTAAGGTGCAGGCTGGGGATGCGCGAGTAATAGGTGGTCATGTGGGTTT

Structures

Antitoxin