Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1395488..1395670 Replicon chromosome
Accession NZ_CP075563
Organism Staphylococcus aureus strain Sta2021027

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag KJP35_RS07055 Protein ID WP_001801861.1
Coordinates 1395575..1395670 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1395488..1395547 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KJP35_RS07040 1394626..1395003 + 378 WP_001037045.1 DUF1433 domain-containing protein -
KJP35_RS07045 1395197..1395373 + 177 Protein_1347 transposase -
KJP35_RS07050 1395351..1395452 - 102 WP_001791893.1 hypothetical protein -
- 1395488..1395547 + 60 - - Antitoxin
KJP35_RS07055 1395575..1395670 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
KJP35_RS07060 1395873..1396016 + 144 WP_001549059.1 transposase -
KJP35_RS07065 1396620..1397003 + 384 WP_000070811.1 hypothetical protein -
KJP35_RS07070 1397014..1397190 + 177 WP_000375477.1 hypothetical protein -
KJP35_RS07075 1397493..1398121 + 629 Protein_1353 ImmA/IrrE family metallo-endopeptidase -
KJP35_RS07080 1398319..1398891 - 573 WP_045177260.1 hypothetical protein -
KJP35_RS07085 1398992..1399333 - 342 WP_045177258.1 DUF3969 family protein -
KJP35_RS07090 1399374..1400000 - 627 WP_045177256.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - hlgA / lukD 1362665..1402560 39895


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T203901 WP_001801861.1 NZ_CP075563:c1395670-1395575 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T203901 NZ_CP100476:c1057579-1057178 [Mesorhizobium sp. C120A]
ATGTTTCTTCTGGACACGAACGTCGTGTCGGGTGCGCGAAAGCGAGAGGGGCCAGTGGCGGATTGGATAATCAAGCAAGA
GCGCCAGTCTCTGTTTCTAAGCGTCATCACGCTCGGTGAAATCGCACGCGGAATCGAAATGAAGCGGCGAAACGACCCCG
ACACTGCAAACCATTTAGCAGCGTGGTTCCACGGTCTGCGCCACAGCTACGAAAACCGAATTCTCGGCATAGACGAGAGC
ATCGCTGCCCAATGGGGTCGCATCTCCGCGATCCGCACGCGCGGCGACGCAGATGGGCTTATAGCCGCGACGGCGCTCTT
CCACGACCTCATACTGGTCACACGCAACGTCGCCGATTTCGACGATACTCGCGTCACAATGTTCAACCCTTGGGAAGCCT
GA

Antitoxin


Download         Length: 60 bp

>AT203901 NZ_CP075563:1395488-1395547 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References