Detailed information of TA system TA202989

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): IasE-IsrA/SymE(toxin)
• Location: 3548854..3549156
• Replicon: chromosome
• Accession: NZ_CP075116
• Organism: Salmonella enterica subsp. enterica serovar Stanleyville strain CFSAN059881

Toxin (Protein)

• Gene name: IasE
• Uniprot ID: -
• Locus tag: CCO40_RS17155
• Protein ID: WP_170930898.1
• Coordinates: 3548854..3549156 (+)
• Length: 101 a.a.

Antitoxin (RNA)

Gene name	IsrA
Locus tag	-
Coordinates	3548897..3549105 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CCO40_RS17115	3544412..3545116	-	705	Protein_3356	integrase core domain-containing protein	-
CCO40_RS17120	3545169..3545342	+	174	WP_001531381.1	hypothetical protein	-
CCO40_RS17125	3545407..3545874	-	468	WP_001284951.1	Imm42 family immunity protein	-
CCO40_RS17130	3545867..3546175	-	309	WP_165488057.1	hypothetical protein	-
CCO40_RS22540	3546166..3546303	-	138	WP_231391191.1	hypothetical protein	-
CCO40_RS17140	3546545..3546808	+	264	WP_000994215.1	hypothetical protein	-
CCO40_RS17145	3546855..3547289	-	435	WP_000789494.1	hypothetical protein	-
CCO40_RS17150	3547286..3548839	-	1554	WP_094897886.1	RHS repeat-associated core domain-containing protein	-
CCO40_RS17155	3548854..3549156	+	303	WP_170930898.1	SymE family type I addiction module toxin	Toxin
-	3548897..3549105	-	209	-	-	Antitoxin
CCO40_RS17160	3549201..3549518	-	318	WP_140428680.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3535260..3572018	36758

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin SymE-like (7-66)

Sequences

Toxin

Protein

• Length: 101 a.a.
• Molecular weight: 11299.94 Da
• Isoelectric Point: 8.8642

>T202989 WP_170930898.1 NZ_CP075116:3548854-3549156 [Salmonella enterica subsp. enterica serovar Stanleyville]
VSISKTQRRYQVGYISVRHENSKTHMTTYYSRIPSLHLKGDWLAEAGFDTGASVTVKISEGCLTLIAERDEVQELREELY
QVKQVVKGMKVGISGVLREV

Nucleotide

• Length: 303 bp

>T202989 NZ_CP099809:545631-545951 [Yersinia ruckeri]
ATGCAAACCACAACTGTACCGGCCACGTTGCCGGTTTCATCACGCCTGTCTCCCGTCCAGGTGTGGCAACAACTGTTAAC
GTATCTACTGGAACACCATTACGGCTTGACGCTTAACGATACGCCATTTCATGATGACGCATCCATAGAGGAACATATCG
AAGCGGGAATAACGCTTGCTGATGCAGTGAATTTCCTGGTTGAACGCTATGAGCTGGTGCGCACTGACCGCAAAGGATTC
ACTTGGCAGGAGCAAACCCCATTTCTGACCGCTACAGATATTCTCAGAGCAAAGCGGGCTACCGGATTAATGAATACGTA
A

Antitoxin

Nucleotide

• Length: 209 bp

>AT202989 NZ_CP075116:c3549105-3548897 [Salmonella enterica subsp. enterica serovar Stanleyville]
CTGTTTAACCTGATAAAGTTCCTCCCGCAGCTCCTGCACCTCGTCGCGCTCCGCAATCAGAGTCAAACACCCCTCGGAGA
TCTTCACGGTCACGCTCGCCCCGGTATCAAATCCCGCTTCTGCCAGCCAGTCGCCCTTAAGGTGCAGGCTGGGGATGCGC
GAGTAATAGGTGGTCATGTGGGTTTTGCTGTTCTCGTGGCGGACGCTGA

Structures

Antitoxin