Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | IasE-IsrA/- |
Location | 3546388..3546808 | Replicon | chromosome |
Accession | NZ_CP075116 | ||
Organism | Salmonella enterica subsp. enterica serovar Stanleyville strain CFSAN059881 |
Toxin (Protein)
Gene name | IasE | Uniprot ID | A0A8E7RAJ3 |
Locus tag | CCO40_RS17140 | Protein ID | WP_000994215.1 |
Coordinates | 3546545..3546808 (+) | Length | 88 a.a. |
Antitoxin (RNA)
Gene name | IsrA | ||
Locus tag | - | ||
Coordinates | 3546388..3546798 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CCO40_RS17105 | 3542336..3543073 | - | 738 | WP_094889352.1 | pili assembly chaperone SafB | - |
CCO40_RS17110 | 3543157..3543651 | - | 495 | WP_061376324.1 | pilus assembly protein | - |
CCO40_RS17115 | 3544412..3545116 | - | 705 | Protein_3356 | integrase core domain-containing protein | - |
CCO40_RS17120 | 3545169..3545342 | + | 174 | WP_001531381.1 | hypothetical protein | - |
CCO40_RS17125 | 3545407..3545874 | - | 468 | WP_001284951.1 | Imm42 family immunity protein | - |
CCO40_RS17130 | 3545867..3546175 | - | 309 | WP_165488057.1 | hypothetical protein | - |
CCO40_RS22540 | 3546166..3546303 | - | 138 | WP_231391191.1 | hypothetical protein | - |
- | 3546388..3546798 | - | 411 | - | - | Antitoxin |
CCO40_RS17140 | 3546545..3546808 | + | 264 | WP_000994215.1 | hypothetical protein | Toxin |
CCO40_RS17145 | 3546855..3547289 | - | 435 | WP_000789494.1 | hypothetical protein | - |
CCO40_RS17150 | 3547286..3548839 | - | 1554 | WP_094897886.1 | RHS repeat-associated core domain-containing protein | - |
CCO40_RS17155 | 3548854..3549156 | + | 303 | WP_170930898.1 | SymE family type I addiction module toxin | - |
CCO40_RS17160 | 3549201..3549518 | - | 318 | WP_140428680.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | - | 3535260..3572018 | 36758 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 88 a.a. Molecular weight: 9458.71 Da Isoelectric Point: 6.4458
>T202986 WP_000994215.1 NZ_CP075116:3546545-3546808 [Salmonella enterica subsp. enterica serovar Stanleyville]
MNASGASVRHINSETCMTTCYSQIPSGDCQEEAGFETGASVVVKISERGLILIAETDEVRDLRKELYQVKKSMKHIKAGV
NNVVNGN
MNASGASVRHINSETCMTTCYSQIPSGDCQEEAGFETGASVVVKISERGLILIAETDEVRDLRKELYQVKKSMKHIKAGV
NNVVNGN
Download Length: 264 bp
>T202986 NZ_CP099808:1936158-1936616 [Yersinia ruckeri]
GTGATGCTCTACCGGATAGTTCACAACCGTTACCTGGCAACGGCCTGGACCGGATATGGCGCAGAAACCTATGGTGGCCG
CTGGAATCATAAAGGCCATGCGGCGATTTATCTGGCCAGTAGCGTTTCTCTGGCGATGCTCGAAACACTGGTGCATGTAG
AAGATAGCGCGACGCTGAACGATTTTAATCTATTTCAGATAACCATTCCCGATAATGCAATTATGGTACTGCAACAGCAA
GATTGGCCACGTGGATGGCGAGATGACCCCCCCCCCGTGGCCACCATGGACATCGGCACCGAATGGATTGGTTCAGTATC
ATCTGTCGGTCTGCTGGTACCATCCACGTTAGTCCCTTTGGAAAGAAATATGCTGGTGAATCCTAAACACCGCGATTTCG
CCTCGTGCCTGAAAAGCATCAATCCACTGACGTTCAGTTTTGATCCTCGTCTAAAGTAA
GTGATGCTCTACCGGATAGTTCACAACCGTTACCTGGCAACGGCCTGGACCGGATATGGCGCAGAAACCTATGGTGGCCG
CTGGAATCATAAAGGCCATGCGGCGATTTATCTGGCCAGTAGCGTTTCTCTGGCGATGCTCGAAACACTGGTGCATGTAG
AAGATAGCGCGACGCTGAACGATTTTAATCTATTTCAGATAACCATTCCCGATAATGCAATTATGGTACTGCAACAGCAA
GATTGGCCACGTGGATGGCGAGATGACCCCCCCCCCGTGGCCACCATGGACATCGGCACCGAATGGATTGGTTCAGTATC
ATCTGTCGGTCTGCTGGTACCATCCACGTTAGTCCCTTTGGAAAGAAATATGCTGGTGAATCCTAAACACCGCGATTTCG
CCTCGTGCCTGAAAAGCATCAATCCACTGACGTTCAGTTTTGATCCTCGTCTAAAGTAA
Antitoxin
Download Length: 411 bp
>AT202986 NZ_CP075116:c3546798-3546388 [Salmonella enterica subsp. enterica serovar Stanleyville]
TTCACCACATTATTTACCCCCGCCTTAATATGCTTCATCGACTTTTTCACCTGATAAAGCTCCTTCCGTAGATCCCTCAC
TTCATCCGTTTCTGCAATCAGGATCAAACCCCGCTCGGAGATCTTCACAACAACGCTCGCCCCGGTCTCAAATCCCGCTT
CTTCCTGGCAGTCGCCGCTGGGGATTTGTGAGTAACAGGTGGTCATGCAGGTTTCGCTGTTGATGTGGCGGACGCTGGCG
CCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTAATTCTCCGCCGGATGCTGGCTGATTGTGGAGCTCAGGGTGAG
CGAGTATGGGCGCGACATCCTGGCACTGAGCCCCCCTCTCCCCGGCCAGCTCCGGGCGGTGATGAGCAACCGGCTGCCGG
GGCCGTATTTT
TTCACCACATTATTTACCCCCGCCTTAATATGCTTCATCGACTTTTTCACCTGATAAAGCTCCTTCCGTAGATCCCTCAC
TTCATCCGTTTCTGCAATCAGGATCAAACCCCGCTCGGAGATCTTCACAACAACGCTCGCCCCGGTCTCAAATCCCGCTT
CTTCCTGGCAGTCGCCGCTGGGGATTTGTGAGTAACAGGTGGTCATGCAGGTTTCGCTGTTGATGTGGCGGACGCTGGCG
CCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTAATTCTCCGCCGGATGCTGGCTGATTGTGGAGCTCAGGGTGAG
CGAGTATGGGCGCGACATCCTGGCACTGAGCCCCCCTCTCCCCGGCCAGCTCCGGGCGGTGATGAGCAACCGGCTGCCGG
GGCCGTATTTT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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