Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) IasE-IsrA/-
Location 3546388..3546808 Replicon chromosome
Accession NZ_CP075116
Organism Salmonella enterica subsp. enterica serovar Stanleyville strain CFSAN059881

Toxin (Protein)


Gene name IasE Uniprot ID A0A8E7RAJ3
Locus tag CCO40_RS17140 Protein ID WP_000994215.1
Coordinates 3546545..3546808 (+) Length 88 a.a.

Antitoxin (RNA)


Gene name IsrA
Locus tag -
Coordinates 3546388..3546798 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CCO40_RS17105 3542336..3543073 - 738 WP_094889352.1 pili assembly chaperone SafB -
CCO40_RS17110 3543157..3543651 - 495 WP_061376324.1 pilus assembly protein -
CCO40_RS17115 3544412..3545116 - 705 Protein_3356 integrase core domain-containing protein -
CCO40_RS17120 3545169..3545342 + 174 WP_001531381.1 hypothetical protein -
CCO40_RS17125 3545407..3545874 - 468 WP_001284951.1 Imm42 family immunity protein -
CCO40_RS17130 3545867..3546175 - 309 WP_165488057.1 hypothetical protein -
CCO40_RS22540 3546166..3546303 - 138 WP_231391191.1 hypothetical protein -
- 3546388..3546798 - 411 - - Antitoxin
CCO40_RS17140 3546545..3546808 + 264 WP_000994215.1 hypothetical protein Toxin
CCO40_RS17145 3546855..3547289 - 435 WP_000789494.1 hypothetical protein -
CCO40_RS17150 3547286..3548839 - 1554 WP_094897886.1 RHS repeat-associated core domain-containing protein -
CCO40_RS17155 3548854..3549156 + 303 WP_170930898.1 SymE family type I addiction module toxin -
CCO40_RS17160 3549201..3549518 - 318 WP_140428680.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3535260..3572018 36758


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 88 a.a.        Molecular weight: 9458.71 Da        Isoelectric Point: 6.4458

>T202986 WP_000994215.1 NZ_CP075116:3546545-3546808 [Salmonella enterica subsp. enterica serovar Stanleyville]
MNASGASVRHINSETCMTTCYSQIPSGDCQEEAGFETGASVVVKISERGLILIAETDEVRDLRKELYQVKKSMKHIKAGV
NNVVNGN

Download         Length: 264 bp

>T202986 NZ_CP099808:1936158-1936616 [Yersinia ruckeri]
GTGATGCTCTACCGGATAGTTCACAACCGTTACCTGGCAACGGCCTGGACCGGATATGGCGCAGAAACCTATGGTGGCCG
CTGGAATCATAAAGGCCATGCGGCGATTTATCTGGCCAGTAGCGTTTCTCTGGCGATGCTCGAAACACTGGTGCATGTAG
AAGATAGCGCGACGCTGAACGATTTTAATCTATTTCAGATAACCATTCCCGATAATGCAATTATGGTACTGCAACAGCAA
GATTGGCCACGTGGATGGCGAGATGACCCCCCCCCCGTGGCCACCATGGACATCGGCACCGAATGGATTGGTTCAGTATC
ATCTGTCGGTCTGCTGGTACCATCCACGTTAGTCCCTTTGGAAAGAAATATGCTGGTGAATCCTAAACACCGCGATTTCG
CCTCGTGCCTGAAAAGCATCAATCCACTGACGTTCAGTTTTGATCCTCGTCTAAAGTAA

Antitoxin


Download         Length: 411 bp

>AT202986 NZ_CP075116:c3546798-3546388 [Salmonella enterica subsp. enterica serovar Stanleyville]
TTCACCACATTATTTACCCCCGCCTTAATATGCTTCATCGACTTTTTCACCTGATAAAGCTCCTTCCGTAGATCCCTCAC
TTCATCCGTTTCTGCAATCAGGATCAAACCCCGCTCGGAGATCTTCACAACAACGCTCGCCCCGGTCTCAAATCCCGCTT
CTTCCTGGCAGTCGCCGCTGGGGATTTGTGAGTAACAGGTGGTCATGCAGGTTTCGCTGTTGATGTGGCGGACGCTGGCG
CCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTAATTCTCCGCCGGATGCTGGCTGATTGTGGAGCTCAGGGTGAG
CGAGTATGGGCGCGACATCCTGGCACTGAGCCCCCCTCTCCCCGGCCAGCTCCGGGCGGTGATGAGCAACCGGCTGCCGG
GGCCGTATTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References