Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yjhX-yjhQ/YjhX-GNAT |
Location | 4178836..4179650 | Replicon | chromosome |
Accession | NZ_CP074680 | ||
Organism | Escherichia coli strain MEI008 |
Toxin (Protein)
Gene name | yjhX | Uniprot ID | S1PA82 |
Locus tag | KIM92_RS20200 | Protein ID | WP_001054376.1 |
Coordinates | 4178836..4179093 (+) | Length | 86 a.a. |
Antitoxin (Protein)
Gene name | yjhQ | Uniprot ID | U9Z4B8 |
Locus tag | KIM92_RS20205 | Protein ID | WP_001309181.1 |
Coordinates | 4179105..4179650 (+) | Length | 182 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
KIM92_RS20175 (4174096) | 4174096..4175076 | + | 981 | WP_000991438.1 | 9-O-acetyl-N-acetylneuraminic acid deacetylase | - |
KIM92_RS20180 (4175186) | 4175186..4175391 | + | 206 | Protein_3949 | HNH endonuclease | - |
KIM92_RS20185 (4175691) | 4175691..4176671 | - | 981 | WP_000019400.1 | IS5-like element IS5 family transposase | - |
KIM92_RS20190 (4176858) | 4176858..4178098 | - | 1241 | Protein_3951 | helicase YjhR | - |
KIM92_RS20195 (4178214) | 4178214..4178345 | + | 132 | WP_001309182.1 | hypothetical protein | - |
KIM92_RS20200 (4178836) | 4178836..4179093 | + | 258 | WP_001054376.1 | YjhX family toxin | Toxin |
KIM92_RS20205 (4179105) | 4179105..4179650 | + | 546 | WP_001309181.1 | N-acetyltransferase | Antitoxin |
KIM92_RS20210 (4179706) | 4179706..4180452 | + | 747 | WP_000354251.1 | class I SAM-dependent methyltransferase | - |
KIM92_RS20215 (4180621) | 4180621..4180839 | + | 219 | Protein_3956 | hypothetical protein | - |
KIM92_RS20220 (4180877) | 4180877..4180993 | + | 117 | Protein_3957 | VOC family protein | - |
KIM92_RS20225 (4181238) | 4181238..4182359 | + | 1122 | WP_000010829.1 | M42 family metallopeptidase | - |
KIM92_RS20230 (4182356) | 4182356..4182634 | + | 279 | WP_000722973.1 | PTS sugar transporter subunit IIB SgcB | - |
KIM92_RS20235 (4182646) | 4182646..4183959 | + | 1314 | WP_000460843.1 | PTS sugar transporter subunit IIC SgcC | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | fimI / fimA / fimE / fimB | 4167423..4187874 | 20451 | |
flank | IS/Tn | - | - | 4175691..4176671 | 980 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 86 a.a. Molecular weight: 9734.29 Da Isoelectric Point: 11.0090
>T202641 WP_001054376.1 NZ_CP074680:4178836-4179093 [Escherichia coli]
MNLSRQEQHTLHVLAKGRRIAHVRDSSGRVTSVECYSREGLLLTDCTLAVFKKLKTKKLIKSVNGQPYRINTTELNKVRA
QLDNR
MNLSRQEQHTLHVLAKGRRIAHVRDSSGRVTSVECYSREGLLLTDCTLAVFKKLKTKKLIKSVNGQPYRINTTELNKVRA
QLDNR
Download Length: 258 bp
>T202641 NZ_CP099542:c3457472-3457375 [Pantoea ananatis]
GCAAGGCGAAAGCCTCTATCAATGCCAACTTTTAGCGCACGGCTCCTTGAGAGCCATTTCCCTGGACCGAATACAGGAAT
CGTGTTCGGTCTTTTTTT
GCAAGGCGAAAGCCTCTATCAATGCCAACTTTTAGCGCACGGCTCCTTGAGAGCCATTTCCCTGGACCGAATACAGGAAT
CGTGTTCGGTCTTTTTTT
Antitoxin
Download Length: 182 a.a. Molecular weight: 19956.90 Da Isoelectric Point: 6.3277
>AT202641 WP_001309181.1 NZ_CP074680:4179105-4179650 [Escherichia coli]
MTVHHFTFHITDKSDASDIREVETRAFGFSKEADLVASLLEDESARPALSLLARYEGKAVGHILFTRATFKGEMDSPLMH
ILAPLAVIPEYQGMGVGGRLIRTGIEHLRLMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMMQSLTA
QPMTLTGHIRCADPDETGALT
MTVHHFTFHITDKSDASDIREVETRAFGFSKEADLVASLLEDESARPALSLLARYEGKAVGHILFTRATFKGEMDSPLMH
ILAPLAVIPEYQGMGVGGRLIRTGIEHLRLMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMMQSLTA
QPMTLTGHIRCADPDETGALT
Download Length: 546 bp
>AT202641 NZ_CP099542:3457375-3457507 [Pantoea ananatis]
AAAAAAAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTCAAGGAGCCGTGCGCTAAAAGTTGGCATTGA
TAGAGGCTTTCGCCTTGCTTTTAAAGCGTAGGACAACGCGCCAGATTTTCCAG
AAAAAAAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTCAAGGAGCCGTGCGCTAAAAGTTGGCATTGA
TAGAGGCTTTCGCCTTGCTTTTAAAGCGTAGGACAACGCGCCAGATTTTCCAG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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