199519

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-MazE
Location 474054..474533 Replicon chromosome
Accession NZ_CP073017
Organism Synechocystis sp. PCC 6803

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag KBZ93_RS02265 Protein ID WP_010871640.1
Coordinates 474054..474305 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag KBZ93_RS02270 Protein ID WP_010871641.1
Coordinates 474306..474533 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KBZ93_RS02245 (KBZ93_02255) 469102..469632 - 531 WP_041425771.1 alpha/beta hydrolase -
KBZ93_RS02250 (KBZ93_02260) 469693..471015 + 1323 WP_010871637.1 hypothetical protein -
KBZ93_RS02255 (KBZ93_02265) 471181..473031 + 1851 WP_010871638.1 ATP-dependent zinc metalloprotease FtsH3 -
KBZ93_RS02260 (KBZ93_02270) 473240..473776 + 537 Protein_450 IS5 family transposase -
KBZ93_RS02265 (KBZ93_02275) 474054..474305 - 252 WP_010871640.1 type II toxin-antitoxin system VapC family toxin Toxin
KBZ93_RS02270 (KBZ93_02280) 474306..474533 - 228 WP_010871641.1 virulence factor Antitoxin
KBZ93_RS02275 (KBZ93_02285) 474612..474893 - 282 WP_020861443.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family -
KBZ93_RS02280 (KBZ93_02290) 474890..475108 - 219 WP_010871642.1 hypothetical protein -
KBZ93_RS02285 (KBZ93_02295) 475211..475546 - 336 WP_010871643.1 DUF86 domain-containing protein -
KBZ93_RS02290 (KBZ93_02300) 475536..475844 - 309 WP_010871644.1 nucleotidyltransferase family protein -
KBZ93_RS02295 (KBZ93_02305) 475974..477500 - 1527 WP_010871645.1 reverse transcriptase domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
flank IS/Tn - - 473515..473763 248


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-80)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9540.13 Da        Isoelectric Point: 7.9952

>T199519 WP_010871640.1 NZ_CP073017:c474305-474054 [Synechocystis sp. PCC 6803]
MKYLLDTNICIYLIKKKPFKVLAKFQTLEISDIGISSITVAELEYGVSKSQQQSKNRDALMQFLMPLEIVEFNSGSGDRL
WQH

Download         Length: 252 bp

>T199519 NZ_CP097370:2707058-2707165 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACAACCTGGCGGCACCGATCCTGGCGGGGATTATTACCGCAGTGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8538.69 Da        Isoelectric Point: 4.2840

>AT199519 WP_010871641.1 NZ_CP073017:c474533-474306 [Synechocystis sp. PCC 6803]
MNTAQISTDGTHQIVILPENFTIAGSEVYIKKIGSTIILIAKNNPWQSLIESLDQFSDDFMKTREQPPLDIREEF

Download         Length: 228 bp

>AT199519 NZ_CP097370:c2707001-2706946 [Escherichia coli]
CAAGATTAGCCCCCGTTCTGTTGTCAGGTTGTACCTCTCAACGTGCGGGGGTTTTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References