Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | txpA-SprF1/- |
Location | 2009243..2009550 | Replicon | chromosome |
Accession | NZ_CP070986 | ||
Organism | Staphylococcus aureus strain WBG8287 |
Toxin (Protein)
Gene name | txpA | Uniprot ID | Q2FWU9 |
Locus tag | JYH18_RS09720 | Protein ID | WP_011447039.1 |
Coordinates | 2009374..2009550 (-) | Length | 59 a.a. |
Antitoxin (RNA)
Gene name | SprF1 | ||
Locus tag | - | ||
Coordinates | 2009243..2009382 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JYH18_RS09680 | 2004808..2004987 | + | 180 | WP_000669791.1 | hypothetical protein | - |
JYH18_RS09685 | 2005298..2005558 | + | 261 | WP_001791826.1 | hypothetical protein | - |
JYH18_RS09690 | 2005611..2005961 | - | 351 | WP_000702263.1 | complement inhibitor SCIN-A | - |
JYH18_RS09695 | 2006473..2006808 | - | 336 | Protein_1872 | SH3 domain-containing protein | - |
JYH18_RS09700 | 2007459..2007950 | - | 492 | WP_000920038.1 | staphylokinase | - |
JYH18_RS09705 | 2008141..2008896 | - | 756 | WP_000861025.1 | CHAP domain-containing protein | - |
JYH18_RS09710 | 2008908..2009162 | - | 255 | WP_000611512.1 | phage holin | - |
JYH18_RS09715 | 2009214..2009321 | + | 108 | WP_031762631.1 | hypothetical protein | - |
- | 2009243..2009382 | + | 140 | NuclAT_0 | - | Antitoxin |
- | 2009243..2009382 | + | 140 | NuclAT_0 | - | Antitoxin |
- | 2009243..2009382 | + | 140 | NuclAT_0 | - | Antitoxin |
- | 2009243..2009382 | + | 140 | NuclAT_0 | - | Antitoxin |
JYH18_RS09720 | 2009374..2009550 | - | 177 | WP_011447039.1 | putative holin-like toxin | Toxin |
JYH18_RS09725 | 2009659..2010432 | - | 774 | WP_000750412.1 | staphylococcal enterotoxin type A | - |
JYH18_RS09730 | 2010805..2011179 | - | 375 | WP_061653202.1 | hypothetical protein | - |
JYH18_RS09735 | 2011235..2011522 | - | 288 | WP_001262621.1 | hypothetical protein | - |
JYH18_RS09740 | 2011568..2011720 | - | 153 | WP_001000058.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Prophage | - | scn / sak / sea / selq / selk / hlb / groEL | 2005611..2064020 | 58409 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 59 a.a. Molecular weight: 6849.45 Da Isoelectric Point: 10.6777
>T194930 WP_011447039.1 NZ_CP070986:c2009550-2009374 [Staphylococcus aureus]
MDRWWLSEYKEVVPMVALLKSLERRRLMITISTMLQFGLFLIALIGLVIKLIELSNKK
MDRWWLSEYKEVVPMVALLKSLERRRLMITISTMLQFGLFLIALIGLVIKLIELSNKK
Download Length: 177 bp
>T194930 NZ_CP094230:476930-477271 [Enterococcus faecium]
GTGTCAGAAGAAAGAATTTATATTCCTAAAAAAGGTGATATTGTATGGATTGATTTTGATCCCTCCGTAGGAAAAGAAAT
TCAAAAAAGACGACCAGGACTAGTCGTCTCTCGTTATGAATTTAACCGTAAAACAATGTTTTCGGTCATATGTCCAATTA
CTTCCACTATAAAGAATTTACCGACACGTTACTCATTACCTGAAGAGCTAGATATAAAAGGACAAGTAATTATTACACAA
TTAAAATCTCTTGATTTTAAGGAACGAAAACTCAAAAAAATAGAAAACTTACCATTGCAAGACATGGCTAAAATTGATCA
GATTATACAGTATATGTTTTAA
GTGTCAGAAGAAAGAATTTATATTCCTAAAAAAGGTGATATTGTATGGATTGATTTTGATCCCTCCGTAGGAAAAGAAAT
TCAAAAAAGACGACCAGGACTAGTCGTCTCTCGTTATGAATTTAACCGTAAAACAATGTTTTCGGTCATATGTCCAATTA
CTTCCACTATAAAGAATTTACCGACACGTTACTCATTACCTGAAGAGCTAGATATAAAAGGACAAGTAATTATTACACAA
TTAAAATCTCTTGATTTTAAGGAACGAAAACTCAAAAAAATAGAAAACTTACCATTGCAAGACATGGCTAAAATTGATCA
GATTATACAGTATATGTTTTAA
Antitoxin
Download Length: 140 bp
>AT194930 NZ_CP070986:2009243-2009382 [Staphylococcus aureus]
ATATATAGAAAAAGGGCAACATGCGCAAACATGTTACCCTAGTGAGCCCGTTAAAAAGACGGTGGCTATTTTAGATTAAA
GATTAAATTAATAACCATTTAACCATCGAAACCAGCCAAAGTTAGCGATGGTTATTTTTT
ATATATAGAAAAAGGGCAACATGCGCAAACATGTTACCCTAGTGAGCCCGTTAAAAAGACGGTGGCTATTTTAGATTAAA
GATTAAATTAATAACCATTTAACCATCGAAACCAGCCAAAGTTAGCGATGGTTATTTTTT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|