Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1850555..1850737 Replicon chromosome
Accession NZ_CP070986
Organism Staphylococcus aureus strain WBG8287

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag JYH18_RS08755 Protein ID WP_001801861.1
Coordinates 1850555..1850650 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1850678..1850737 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JYH18_RS08720 1846225..1846851 + 627 WP_000669017.1 hypothetical protein -
JYH18_RS08725 1846892..1847233 + 342 WP_000627541.1 DUF3969 family protein -
JYH18_RS08730 1847334..1847906 + 573 WP_000414202.1 hypothetical protein -
JYH18_RS08735 1848104..1848661 - 558 Protein_1718 ImmA/IrrE family metallo-endopeptidase -
JYH18_RS08740 1849035..1849211 - 177 WP_000375477.1 hypothetical protein -
JYH18_RS08745 1849222..1849605 - 384 WP_000070814.1 hypothetical protein -
JYH18_RS08750 1850209..1850352 - 144 WP_001549059.1 transposase -
JYH18_RS08755 1850555..1850650 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1850678..1850737 - 60 - - Antitoxin
JYH18_RS08760 1850773..1850874 + 102 WP_001791893.1 hypothetical protein -
JYH18_RS08765 1850852..1851028 - 177 Protein_1724 transposase -
JYH18_RS08770 1851222..1851599 - 378 Protein_1725 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA 1843666..1883839 40173


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T194927 WP_001801861.1 NZ_CP070986:1850555-1850650 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T194927 NZ_CP094228:c131771-131301 [Klebsiella pneumoniae]
GTGATCTTCTACAGGCTGACGAAAACAAAGTATCTTTCTACGGCCTGGACCGGATATGGTGCGAAAGAGGCTGGTGGGCG
CTGGAATAGCGTGGGGGTGTCAATGGTATATGTCTCCGAAACGGCATCACTAACGATGCTGGAGACCCTGGTACACCTGC
ATGCGGCACAGATAATGGACTCTTTCACGCTACTGAGTATCGATGTGCCTGATGAACTGATACAAAGCGCAAACATGGAT
GAATTACCGGGCAACTGGGCTGATGAGGATGCGCCTCAGGAACTGGCTGATTACGGAGATGCCTGGTCATTTACCAGGAG
CTCGGTTGCACTGCGTGTTCCCTCAGCCTTATCGCCGGTAGAGTTCAATTATCTGTTAAATCCTGAGCACCCTGAGTTTT
ACGGGATCGTGCAGAAGGCTCAACAGATACCGTTCCGGTTTGATAGTCGTCTTAAACCTGACAGGAAGTGA

Antitoxin


Download         Length: 60 bp

>AT194927 NZ_CP070986:c1850737-1850678 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References