Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 933162..933344 Replicon chromosome
Accession NZ_CP068143
Organism Staphylococcus aureus strain FDAARGOS_1086

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag I6I43_RS04890 Protein ID WP_001801861.1
Coordinates 933249..933344 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 933162..933221 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6I43_RS04875 932300..932677 + 378 WP_001037045.1 DUF1433 domain-containing protein -
I6I43_RS04880 932871..933047 + 177 Protein_921 transposase -
I6I43_RS04885 933025..933126 - 102 WP_001791893.1 hypothetical protein -
- 933162..933221 + 60 - - Antitoxin
I6I43_RS04890 933249..933344 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
I6I43_RS04895 933547..933690 + 144 WP_001549059.1 transposase -
I6I43_RS04900 934294..934677 + 384 WP_000070811.1 hypothetical protein -
I6I43_RS04905 934688..934864 + 177 WP_000375477.1 hypothetical protein -
I6I43_RS04910 935238..935795 + 558 WP_045177261.1 ImmA/IrrE family metallo-endopeptidase -
I6I43_RS04915 935993..936565 - 573 WP_045177260.1 hypothetical protein -
I6I43_RS04920 936666..937007 - 342 WP_045177258.1 DUF3969 family protein -
I6I43_RS04925 937048..937674 - 627 WP_045177256.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - hlgA / lukD 900318..939440 39122


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T186692 WP_001801861.1 NZ_CP068143:c933344-933249 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T186692 NZ_CP089742:3081124-3081408 [Melaminivora jejuensis]
GTGGCCCGGACGCTGGAAGAGACCAGCCAGTTCAAGCGCGACAAAAAGCGCATCAAAGGCTCCGGGCGCCACGACTGGGA
GAAGATGCGGACGGTCGTTACAGAACTGATGAACGACCGGCCTCTGGCGCCCAAACACCGTGACCACGATTTGGTGGGCG
ACTACGTCGGAGTGCGCGAGTGCCACATCACGCCCGATTGGCTGCTCATCTATGACAAGGAAGGGCCACTCCCCACGGGT
TCGCTCAGACTCATCCGCACCGGCTCGCACAGCGAGCTGTTTTGA

Antitoxin


Download         Length: 60 bp

>AT186692 NZ_CP068143:933162-933221 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References