Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | sprA1-sprA1AS/- |
Location | 933162..933344 | Replicon | chromosome |
Accession | NZ_CP068143 | ||
Organism | Staphylococcus aureus strain FDAARGOS_1086 |
Toxin (Protein)
Gene name | sprA1 | Uniprot ID | - |
Locus tag | I6I43_RS04890 | Protein ID | WP_001801861.1 |
Coordinates | 933249..933344 (-) | Length | 32 a.a. |
Antitoxin (RNA)
Gene name | sprA1AS | ||
Locus tag | - | ||
Coordinates | 933162..933221 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
I6I43_RS04875 | 932300..932677 | + | 378 | WP_001037045.1 | DUF1433 domain-containing protein | - |
I6I43_RS04880 | 932871..933047 | + | 177 | Protein_921 | transposase | - |
I6I43_RS04885 | 933025..933126 | - | 102 | WP_001791893.1 | hypothetical protein | - |
- | 933162..933221 | + | 60 | - | - | Antitoxin |
I6I43_RS04890 | 933249..933344 | - | 96 | WP_001801861.1 | type I toxin-antitoxin system Fst family toxin PepA1 | Toxin |
I6I43_RS04895 | 933547..933690 | + | 144 | WP_001549059.1 | transposase | - |
I6I43_RS04900 | 934294..934677 | + | 384 | WP_000070811.1 | hypothetical protein | - |
I6I43_RS04905 | 934688..934864 | + | 177 | WP_000375477.1 | hypothetical protein | - |
I6I43_RS04910 | 935238..935795 | + | 558 | WP_045177261.1 | ImmA/IrrE family metallo-endopeptidase | - |
I6I43_RS04915 | 935993..936565 | - | 573 | WP_045177260.1 | hypothetical protein | - |
I6I43_RS04920 | 936666..937007 | - | 342 | WP_045177258.1 | DUF3969 family protein | - |
I6I43_RS04925 | 937048..937674 | - | 627 | WP_045177256.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Prophage | - | hlgA / lukD | 900318..939440 | 39122 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 32 a.a. Molecular weight: 3554.32 Da Isoelectric Point: 10.4449
>T186692 WP_001801861.1 NZ_CP068143:c933344-933249 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK
Download Length: 96 bp
>T186692 NZ_CP089742:3081124-3081408 [Melaminivora jejuensis]
GTGGCCCGGACGCTGGAAGAGACCAGCCAGTTCAAGCGCGACAAAAAGCGCATCAAAGGCTCCGGGCGCCACGACTGGGA
GAAGATGCGGACGGTCGTTACAGAACTGATGAACGACCGGCCTCTGGCGCCCAAACACCGTGACCACGATTTGGTGGGCG
ACTACGTCGGAGTGCGCGAGTGCCACATCACGCCCGATTGGCTGCTCATCTATGACAAGGAAGGGCCACTCCCCACGGGT
TCGCTCAGACTCATCCGCACCGGCTCGCACAGCGAGCTGTTTTGA
GTGGCCCGGACGCTGGAAGAGACCAGCCAGTTCAAGCGCGACAAAAAGCGCATCAAAGGCTCCGGGCGCCACGACTGGGA
GAAGATGCGGACGGTCGTTACAGAACTGATGAACGACCGGCCTCTGGCGCCCAAACACCGTGACCACGATTTGGTGGGCG
ACTACGTCGGAGTGCGCGAGTGCCACATCACGCCCGATTGGCTGCTCATCTATGACAAGGAAGGGCCACTCCCCACGGGT
TCGCTCAGACTCATCCGCACCGGCTCGCACAGCGAGCTGTTTTGA
Antitoxin
Download Length: 60 bp
>AT186692 NZ_CP068143:933162-933221 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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