Detailed information of TA system TA185233

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): IasE-IsrA/-
• Location: 1257893..1258313
• Replicon: chromosome
• Accession: NZ_CP066851
• Organism: Salmonella enterica subsp. enterica serovar Heidelberg strain SH-2813-Parental

Toxin (Protein)

• Gene name: IasE
• Uniprot ID: A0A8E7RAJ3
• Locus tag: JIG31_RS05825
• Protein ID: WP_000994215.1
• Coordinates: 1257893..1258156 (-)
• Length: 88 a.a.

Antitoxin (RNA)

Gene name	IsrA
Locus tag	-
Coordinates	1257903..1258313 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JIG31_RS05820	1257412..1257846	+	435	WP_000789494.1	hypothetical protein	-
JIG31_RS05825	1257893..1258156	-	264	WP_000994215.1	hypothetical protein	Toxin
-	1257903..1258313	+	411	-	-	Antitoxin
JIG31_RS23230	1258398..1258535	+	138	WP_231391191.1	hypothetical protein	-
JIG31_RS23235	1258526..1258834	+	309	WP_165488057.1	hypothetical protein	-
JIG31_RS05835	1258827..1259294	+	468	WP_001284951.1	Imm42 family immunity protein	-
JIG31_RS05840	1259359..1259532	-	174	WP_001531381.1	hypothetical protein	-
JIG31_RS05845	1259585..1259771	+	187	Protein_1150	transposase	-
JIG31_RS05850	1259811..1260368	-	558	Protein_1151	ATP-binding protein	-
JIG31_RS05855	1261404..1262114	+	711	WP_001009508.1	fimbrial chaperone TcfA	-
JIG31_RS05860	1262222..1262740	+	519	WP_001056552.1	fimbrial protein TcfB	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1235234..1270403	35169

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 88 a.a.
• Molecular weight: 9458.71 Da
• Isoelectric Point: 6.4458

>T185233 WP_000994215.1 NZ_CP066851:c1258156-1257893 [Salmonella enterica subsp. enterica serovar Heidelberg]
MNASGASVRHINSETCMTTCYSQIPSGDCQEEAGFETGASVVVKISERGLILIAETDEVRDLRKELYQVKKSMKHIKAGV
NNVVNGN

Nucleotide

• Length: 264 bp

>T185233 NZ_CP088119:c1231151-1230789 [Enterobacter kobei]
ATGTGGAATGTCGAGACAACGGACAGATTTGATCAATGGTACTTCGAACAAACAACAGCATTAAAAGAAGATGTGCTAGC
GATGATGCATATTCTTGCTGAGTTTGGCCCAACGCTTGGGCGGCCATACGTAGATACCGTGAAGGCTTCAGCCTACGCAA
ACATGAAAGAGTTACGGATTCAACATGCGGGAAATCCCATCAGAGCCTTTTTTGCTTTTGATCCTGACCGTAAGGCAATT
GTGCTCTGTGCTGGAGATAAAACCGGTTGCAATCAAAAACTGTTTTATAACGAAATGATTACGCTGGCTGACGTTGAGTA
CAGCAGACATCTGGCGGATAAGGAGGCCATATGGCAACGCTAA

Antitoxin

Nucleotide

• Length: 411 bp

>AT185233 NZ_CP066851:1257903-1258313 [Salmonella enterica subsp. enterica serovar Heidelberg]
TTCACCACATTATTTACCCCCGCCTTAATATGCTTCATCGACTTTTTCACCTGATAAAGCTCCTTCCGTAGATCCCTCAC
TTCATCCGTTTCTGCAATCAGGATCAAACCCCGCTCGGAGATCTTCACAACAACGCTCGCCCCGGTCTCAAATCCCGCTT
CTTCCTGGCAGTCGCCGCTGGGGATTTGTGAGTAACAGGTGGTCATGCAGGTTTCGCTGTTGATGTGGCGGACGCTGGCG
CCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTAATTCTCCGCCGGATGCTGGCTGATTGTGGAGCTCAGGGTGAG
CGAGTATGGGCGCGACATCCTGGCACTGAGCCCCCCTCTCCCCGGCCAGCTCCGGGCGGTGATGAGCAACCGGCTGCCGG
GGCCGTATTTT

Structures

Antitoxin