Detailed information of TA system TA181404

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): IasE-IsrA/SymE(toxin)
• Location: 3608565..3608800
• Replicon: chromosome
• Accession: NZ_CP064674
• Organism: Salmonella sp. SJTUF14076

Toxin (Protein)

• Gene name: IasE
• Uniprot ID: -
• Locus tag: HU143_RS17565
• Protein ID: WP_051129376.1
• Coordinates: 3608573..3608800 (+)
• Length: 76 a.a.

Antitoxin (RNA)

Gene name	IsrA
Locus tag	-
Coordinates	3608565..3608790 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HU143_RS17545	3605077..3605817	-	741	WP_051129375.1	pili assembly chaperone SafB	-
HU143_RS17550	3605892..3606389	-	498	WP_051129374.1	Saf-pilin pilus formation protein SafA	-
HU143_RS17555	3606522..3607016	-	495	WP_051129373.1	hypothetical protein	-
HU143_RS17560	3607784..3608485	-	702	Protein_3436	IS481 family transposase	-
-	3608565..3608790	-	226	-	-	Antitoxin
HU143_RS17565	3608573..3608800	+	228	WP_051129376.1	SymE family type I addiction module toxin	Toxin
HU143_RS17570	3608846..3609310	-	465	WP_127201574.1	hypothetical protein	-
HU143_RS17575	3609691..3610536	-	846	Protein_3439	RHS repeat protein	-
HU143_RS17580	3610556..3610693	+	138	WP_023227287.1	hypothetical protein	-
HU143_RS17585	3610836..3611444	-	609	WP_053505599.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3592571..3632996	40425
	-	flank	IS/Tn	-	-	3607784..3608062	278

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin SymE-like (5-40)

Sequences

Toxin

Protein

• Length: 76 a.a.
• Molecular weight: 8418.65 Da
• Isoelectric Point: 7.1623

>T181404 WP_051129376.1 NZ_CP064674:3608573-3608800 [Salmonella sp. SJTUF14076]
MTTYYSRIPSLHLKGDWLAEAGFDTGASVTVKISEGCLTLIVETDEVRDLRRELYQVKKSMKHIKAGVYDVVNGN

Nucleotide

• Length: 228 bp

>T181404 NZ_CP085841:c2342853-2342737 [Enterococcus faecalis]
ATGTTTTTGTCCGTTGAAGCAGCGCTAGGACTGATGATTGGTTTTGCAACACTTGTTGTGACCATTATCTTCGGTATCTT
AGCGCTTGTCTTAGACAACAAAAATAACCGTTCATAA

Antitoxin

Nucleotide

• Length: 226 bp

>AT181404 NZ_CP064674:c3608790-3608565 [Salmonella sp. SJTUF14076]
TTCACCACATCATATACCCCCGCCTTAATGTGCTTCATCGACTTTTTCACCTGATAAAGCTCCCTCCGTAGATCCCTCAC
TTCGTCTGTCTCCACAATCAGAGTCAAACACCCTTCGGAGATCTTCACGGTCACGCTCGCCCCGGTATCAAATCCCGCTT
CTGCCAGCCAGTCGCCCTTAAGGTGCAGGCTGGGGATGCGCGAGTAATAGGTGGTCATGTGGGTTT

Structures

Antitoxin