Detailed information of TA system TA181384

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): IasE-IsrA/SymE(toxin)
• Location: 3674605..3674840
• Replicon: chromosome
• Accession: NZ_CP064672
• Organism: Salmonella sp. SJTUF14146

Toxin (Protein)

• Gene name: IasE
• Uniprot ID: -
• Locus tag: IVP14_RS17935
• Protein ID: WP_051129376.1
• Coordinates: 3674613..3674840 (+)
• Length: 76 a.a.

Antitoxin (RNA)

Gene name	IsrA
Locus tag	-
Coordinates	3674605..3674830 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IVP14_RS17915	3671117..3671857	-	741	WP_051129375.1	pili assembly chaperone SafB	-
IVP14_RS17920	3671932..3672429	-	498	WP_051129374.1	Saf-pilin pilus formation protein SafA	-
IVP14_RS17925	3672562..3673056	-	495	WP_051129373.1	hypothetical protein	-
IVP14_RS17930	3673824..3674525	-	702	Protein_3510	IS481 family transposase	-
-	3674605..3674830	-	226	-	-	Antitoxin
IVP14_RS17935	3674613..3674840	+	228	WP_051129376.1	SymE family type I addiction module toxin	Toxin
IVP14_RS17940	3674886..3675350	-	465	WP_127201574.1	hypothetical protein	-
IVP14_RS17945	3675731..3676576	-	846	Protein_3513	RHS repeat protein	-
IVP14_RS17950	3676596..3676733	+	138	WP_023227287.1	hypothetical protein	-
IVP14_RS17955	3676876..3677484	-	609	WP_053505599.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3654721..3699036	44315
	-	flank	IS/Tn	-	-	3673824..3674102	278

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin SymE-like (5-40)

Sequences

Toxin

Protein

• Length: 76 a.a.
• Molecular weight: 8418.65 Da
• Isoelectric Point: 7.1623

>T181384 WP_051129376.1 NZ_CP064672:3674613-3674840 [Salmonella sp. SJTUF14146]
MTTYYSRIPSLHLKGDWLAEAGFDTGASVTVKISEGCLTLIVETDEVRDLRRELYQVKKSMKHIKAGVYDVVNGN

Nucleotide

• Length: 228 bp

>T181384 NZ_CP085823:c3831589-3831332 [Salmonella enterica subsp. enterica serovar Enteritidis]
ATGAATGCCTCCGGCGTCAGCGTCCGCCACATCAACAGCAAAACCCACATGACCACCTATTACTCACAAATCCCCAGCCT
GCATCTTAAGGGCGACTGGCTGGAAGAAGCGGGATTTAAGACCGGGCGCGGCGTCACCGTGAAGATTTCACAGGGGTGTA
TTGTGCTGATGGCGGACAGTAACGAGGAGCAGAAGCTGCGCGAGCAGCTTTATCAGGCTAAACAGGTGGTTAAGGGAATT
AAGGACGTGCTGGTTTAG

Antitoxin

Nucleotide

• Length: 226 bp

>AT181384 NZ_CP064672:c3674830-3674605 [Salmonella sp. SJTUF14146]
TTCACCACATCATATACCCCCGCCTTAATGTGCTTCATCGACTTTTTCACCTGATAAAGCTCCCTCCGTAGATCCCTCAC
TTCGTCTGTCTCCACAATCAGAGTCAAACACCCTTCGGAGATCTTCACGGTCACGCTCGCCCCGGTATCAAATCCCGCTT
CTGCCAGCCAGTCGCCCTTAAGGTGCAGGCTGGGGATGCGCGAGTAATAGGTGGTCATGTGGGTTT

Structures

Antitoxin