Detailed information of TA system TA181364

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): IasE-IsrA/SymE(toxin)
• Location: 3808896..3809131
• Replicon: chromosome
• Accession: NZ_CP064671
• Organism: Salmonella sp. SJTUF14152

Toxin (Protein)

• Gene name: IasE
• Uniprot ID: -
• Locus tag: IVP15_RS18835
• Protein ID: WP_051129376.1
• Coordinates: 3808904..3809131 (+)
• Length: 76 a.a.

Antitoxin (RNA)

Gene name	IsrA
Locus tag	-
Coordinates	3808896..3809121 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IVP15_RS18805	3804072..3804812	-	741	WP_051129375.1	pili assembly chaperone SafB	-
IVP15_RS18810	3804887..3805384	-	498	WP_051129374.1	Saf-pilin pilus formation protein SafA	-
IVP15_RS18815	3805517..3806011	-	495	WP_051129373.1	hypothetical protein	-
IVP15_RS18820	3806779..3807325	-	547	Protein_3686	transposase family protein	-
IVP15_RS18825	3807416..3808644	+	1229	WP_089541817.1	IS3 family transposase	-
IVP15_RS18830	3808670..3808816	-	147	Protein_3688	transposase	-
-	3808896..3809121	-	226	-	-	Antitoxin
IVP15_RS18835	3808904..3809131	+	228	WP_051129376.1	SymE family type I addiction module toxin	Toxin
IVP15_RS18840	3809177..3809641	-	465	WP_195184474.1	hypothetical protein	-
IVP15_RS18845	3810022..3810867	-	846	Protein_3691	RHS repeat protein	-
IVP15_RS18850	3810887..3811024	+	138	WP_023227287.1	hypothetical protein	-
IVP15_RS18855	3811167..3811775	-	609	WP_053505599.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3787676..3833327	45651

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin SymE-like (5-40)

Sequences

Toxin

Protein

• Length: 76 a.a.
• Molecular weight: 8418.65 Da
• Isoelectric Point: 7.1623

>T181364 WP_051129376.1 NZ_CP064671:3808904-3809131 [Salmonella sp. SJTUF14152]
MTTYYSRIPSLHLKGDWLAEAGFDTGASVTVKISEGCLTLIVETDEVRDLRRELYQVKKSMKHIKAGVYDVVNGN

Nucleotide

• Length: 228 bp

>T181364 NZ_CP085822:3714767-3715252 [Salmonella enterica subsp. enterica serovar Enteritidis]
GTGGGACGTGTAACAGCACCAGAACCTTTGTCCGCTTTTCATCAGGTAGCTGAGTTCGTCAGCGGTGAAGCTGTGCTCGA
TGACTGGTTGAAGCAAAAGGGCCTCAAAAACCAGGCTCTCGGAGCGGCCAGAACATTTGTGGTGTGCAAGAAAGACACGA
AGCAAGTAGCCGGTTTTTACTCTCTGGCCACCGGTAGCGTCAACCATACAGAAGTGACAGGCAACCTTCGGCGTAACATG
CCAGATCCCATCCCTGTCATTATACTTGCCCGTCTTGCTGTCGATCTCTCATTCCATGGAAAAGGGCTTGGTGCTGATTT
ACTTCATGATGCAGTGCTTCGTTGCTATCGGGTTGCCGAGAATATTGGTGTACGTGCAATCATGGTTCATGCACTTACCG
AAGAAGCCAAAAATTTCTACATTCACCATGGTTTCAAATCATCACAAACTCAGCAGCGAACATTGTTCCTTAGGCTCCCT
CAATAG

Antitoxin

Nucleotide

• Length: 226 bp

>AT181364 NZ_CP064671:c3809121-3808896 [Salmonella sp. SJTUF14152]
TTCACCACATCATATACCCCCGCCTTAATGTGCTTCATCGACTTTTTCACCTGATAAAGCTCCCTCCGTAGATCCCTCAC
TTCGTCTGTCTCCACAATCAGAGTCAAACACCCTTCGGAGATCTTCACGGTCACGCTCGCCCCGGTATCAAATCCCGCTT
CTGCCAGCCAGTCGCCCTTAAGGTGCAGGCTGGGGATGCGCGAGTAATAGGTGGTCATGTGGGTTT

Structures

Antitoxin