Detailed information of TA system TA181342

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): IasE-IsrA/SymE(toxin)
• Location: 3627997..3628232
• Replicon: chromosome
• Accession: NZ_CP064666
• Organism: Salmonella sp. SJTUF14154

Toxin (Protein)

• Gene name: IasE
• Uniprot ID: -
• Locus tag: IVP16_RS17640
• Protein ID: WP_051129376.1
• Coordinates: 3628005..3628232 (+)
• Length: 76 a.a.

Antitoxin (RNA)

Gene name	IsrA
Locus tag	-
Coordinates	3627997..3628222 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IVP16_RS17620	3624509..3625249	-	741	WP_051129375.1	pili assembly chaperone SafB	-
IVP16_RS17625	3625324..3625821	-	498	WP_051129374.1	Saf-pilin pilus formation protein SafA	-
IVP16_RS17630	3625954..3626448	-	495	WP_051129373.1	hypothetical protein	-
IVP16_RS17635	3627216..3627917	-	702	Protein_3451	IS481 family transposase	-
-	3627997..3628222	-	226	-	-	Antitoxin
IVP16_RS17640	3628005..3628232	+	228	WP_051129376.1	SymE family type I addiction module toxin	Toxin
IVP16_RS17645	3628278..3628742	-	465	WP_127201574.1	hypothetical protein	-
IVP16_RS17650	3629123..3629968	-	846	Protein_3454	RHS repeat protein	-
IVP16_RS17655	3629988..3630125	+	138	WP_023227287.1	hypothetical protein	-
IVP16_RS17660	3630268..3630876	-	609	WP_053505599.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3608113..3652428	44315
	-	flank	IS/Tn	-	-	3627216..3627494	278

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin SymE-like (5-40)

Sequences

Toxin

Protein

• Length: 76 a.a.
• Molecular weight: 8418.65 Da
• Isoelectric Point: 7.1623

>T181342 WP_051129376.1 NZ_CP064666:3628005-3628232 [Salmonella sp. SJTUF14154]
MTTYYSRIPSLHLKGDWLAEAGFDTGASVTVKISEGCLTLIVETDEVRDLRRELYQVKKSMKHIKAGVYDVVNGN

Nucleotide

• Length: 228 bp

>T181342 NZ_CP085821:c730706-730449 [Salmonella enterica subsp. enterica serovar Enteritidis]
ATGAATGCCTCCGGCGTCAGCGTCCGCCACATCAACAGCAAAACCCACATGACCACCTATTACTCACAAATCCCCAGCCT
GCATCTTAAGGGCGACTGGCTGGAAGAAGCGGGATTTAAGACCGGGCGCGGCGTCACCGTGAAGATTTCACAGGGGTGTA
TTGTGCTGATGGCGGACAGTAACGAGGAGCAGAAGCTGCGCGAGCAGCTTTATCAGGCTAAACAGGTGGTTAAGGGAATT
AAGGACGTGCTGGTTTAG

Antitoxin

Nucleotide

• Length: 226 bp

>AT181342 NZ_CP064666:c3628222-3627997 [Salmonella sp. SJTUF14154]
TTCACCACATCATATACCCCCGCCTTAATGTGCTTCATCGACTTTTTCACCTGATAAAGCTCCCTCCGTAGATCCCTCAC
TTCGTCTGTCTCCACAATCAGAGTCAAACACCCTTCGGAGATCTTCACGGTCACGCTCGCCCCGGTATCAAATCCCGCTT
CTGCCAGCCAGTCGCCCTTAAGGTGCAGGCTGGGGATGCGCGAGTAATAGGTGGTCATGTGGGTTT

Structures

Antitoxin