Detailed information of TA system TA181323

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): IasE-IsrA/SymE(toxin)
• Location: 3655103..3655338
• Replicon: chromosome
• Accession: NZ_CP064663
• Organism: Salmonella sp. SJTUF14170

Toxin (Protein)

• Gene name: IasE
• Uniprot ID: -
• Locus tag: IVP17_RS17900
• Protein ID: WP_051129376.1
• Coordinates: 3655111..3655338 (+)
• Length: 76 a.a.

Antitoxin (RNA)

Gene name	IsrA
Locus tag	-
Coordinates	3655103..3655328 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IVP17_RS17880	3651606..3652346	-	741	WP_051129375.1	pili assembly chaperone SafB	-
IVP17_RS17885	3652421..3652918	-	498	WP_064163159.1	Saf-pilin pilus formation protein SafA	-
IVP17_RS17890	3653051..3653545	-	495	WP_051129373.1	hypothetical protein	-
IVP17_RS17895	3654322..3655023	-	702	Protein_3502	IS481 family transposase	-
-	3655103..3655328	-	226	-	-	Antitoxin
IVP17_RS17900	3655111..3655338	+	228	WP_051129376.1	SymE family type I addiction module toxin	Toxin
IVP17_RS17905	3655384..3655848	-	465	WP_127201574.1	hypothetical protein	-
IVP17_RS17910	3656229..3657074	-	846	Protein_3505	RHS repeat protein	-
IVP17_RS17915	3657094..3657231	+	138	WP_023227287.1	hypothetical protein	-
IVP17_RS17920	3657374..3657982	-	609	WP_053505599.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3635210..3679866	44656
	-	flank	IS/Tn	-	-	3654322..3654600	278

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin SymE-like (5-40)

Sequences

Toxin

Protein

• Length: 76 a.a.
• Molecular weight: 8418.65 Da
• Isoelectric Point: 7.1623

>T181323 WP_051129376.1 NZ_CP064663:3655111-3655338 [Salmonella sp. SJTUF14170]
MTTYYSRIPSLHLKGDWLAEAGFDTGASVTVKISEGCLTLIVETDEVRDLRRELYQVKKSMKHIKAGVYDVVNGN

Nucleotide

• Length: 228 bp

>T181323 NZ_CP085819:4358612-4358896 [Salmonella enterica subsp. enterica serovar Typhimurium]
ATGACTTATAAGCTGGCATTTAACGAATCAGCACTAAAAGAGTGGAAAAAACTGGGTCATACCATACAGGAACAGTTTAA
AAAAAAGCTAAGGGAACGGCTTGAAAACCCTCGGGTTCCGGCTTCTCAATTACATGGAAGAAAGGATCAGTACAAAATTA
AGCTGCGTGGTGCAGGATACAGGCTGGTGTACAGCGTCGAAGATGAAATTATCACGGTAACTGTCATTGGTGTTGGAAAG
CGTGAAAATGATGCCGTCTACAAAATGACACGACACAGAAGCTAA

Antitoxin

Nucleotide

• Length: 226 bp

>AT181323 NZ_CP064663:c3655328-3655103 [Salmonella sp. SJTUF14170]
TTCACCACATCATATACCCCCGCCTTAATGTGCTTCATCGACTTTTTCACCTGATAAAGCTCCCTCCGTAGATCCCTCAC
TTCGTCTGTCTCCACAATCAGAGTCAAACACCCTTCGGAGATCTTCACGGTCACGCTCGCCCCGGTATCAAATCCCGCTT
CTGCCAGCCAGTCGCCCTTAAGGTGCAGGCTGGGGATGCGCGAGTAATAGGTGGTCATGTGGGTTT

Structures

Antitoxin