Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) fst-RNAII/-
Location 1097332..1097526 Replicon chromosome
Accession NZ_CP064374
Organism Enterococcus faecalis strain PartL-Efaecalis-RM8376

Toxin (Protein)


Gene name fst Uniprot ID -
Locus tag IUJ47_RS05365 Protein ID WP_142954371.1
Coordinates 1097431..1097526 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name RNAII
Locus tag -
Coordinates 1097332..1097396 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IUJ47_RS05350 1092956..1094704 + 1749 WP_002403688.1 PTS transporter subunit EIIC -
IUJ47_RS05355 1094695..1096728 + 2034 WP_002355275.1 BglG family transcription antiterminator -
IUJ47_RS05360 1096739..1097173 + 435 WP_002355276.1 PTS sugar transporter subunit IIA -
- 1097332..1097396 + 65 - - Antitoxin
IUJ47_RS05365 1097431..1097526 - 96 WP_142954371.1 type I toxin-antitoxin system Fst family toxin Toxin
IUJ47_RS05370 1097772..1099544 + 1773 WP_002387897.1 PTS mannitol-specific transporter subunit IIBC -
IUJ47_RS05375 1099559..1099996 + 438 WP_002355279.1 PTS sugar transporter subunit IIA -
IUJ47_RS05380 1100011..1101165 + 1155 WP_002355280.1 mannitol-1-phosphate 5-dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
flank IS/Tn - - 1101294..1102097 803


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3645.44 Da        Isoelectric Point: 4.6275

>T181001 WP_142954371.1 NZ_CP064374:c1097526-1097431 [Enterococcus faecalis]
MYEIVTKVLVPIFVGIVLKLVTIWLEKQNEE

Download         Length: 96 bp

>T181001 NZ_CP085797:c3537539-3537384 [Salmonella enterica subsp. enterica serovar Enteritidis]
ATGAAGCAGCAAAAGGCGATGTTAATCGCCCTGATCGTCATCTGTTTAACCGTCATAGTGACGGCACTGGTAACGAGGAA
AGACCTCTGCGAGGTACGAATCCGAACCGGCCAGACGGAGGTCGCTGTCTTCACAGCTTACGAACCTGAGGAGTAA

Antitoxin


Download         Length: 65 bp

>AT181001 NZ_CP064374:1097332-1097396 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGCGGTAGGGTGTCTTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References