Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 179043..179225 Replicon chromosome
Accession NZ_CP062376
Organism Staphylococcus aureus strain NAS_AN_099

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag IF707_RS01080 Protein ID WP_001801861.1
Coordinates 179130..179225 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 179043..179102 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IF707_RS01065 178181..178558 + 378 WP_001037045.1 DUF1433 domain-containing protein -
IF707_RS01070 178752..178928 + 177 Protein_173 transposase -
IF707_RS01075 178906..179007 - 102 WP_001791893.1 hypothetical protein -
- 179043..179102 + 60 - - Antitoxin
IF707_RS01080 179130..179225 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
IF707_RS01085 179428..179571 + 144 WP_001549059.1 transposase -
IF707_RS01090 180175..180558 + 384 WP_000070811.1 hypothetical protein -
IF707_RS01095 180569..180745 + 177 WP_000375477.1 hypothetical protein -
IF707_RS01100 181048..181676 + 629 Protein_179 ImmA/IrrE family metallo-endopeptidase -
IF707_RS01105 181874..182446 - 573 WP_045177260.1 hypothetical protein -
IF707_RS01110 182547..182888 - 342 WP_045177258.1 DUF3969 family protein -
IF707_RS01115 182929..183555 - 627 WP_045177256.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - hlgA / lukD 146199..186115 39916


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T174690 WP_001801861.1 NZ_CP062376:c179225-179130 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T174690 NZ_CP081351:2278797-2278900 [Klebsiella michiganensis]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 60 bp

>AT174690 NZ_CP062376:179043-179102 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References