Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrE-as-bsrE/-
Location 2069817..2070132 Replicon chromosome
Accession NZ_CP058242
Organism Bacillus subtilis strain SP1

Toxin (Protein)


Gene name bsrE Uniprot ID -
Locus tag HWV68_RS10310 Protein ID WP_120322743.1
Coordinates 2069817..2069978 (+) Length 54 a.a.

Antitoxin (RNA)


Gene name as-bsrE
Locus tag -
Coordinates 2069959..2070132 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HWV68_RS10295 2065045..2065380 + 336 WP_009967409.1 hypothetical protein -
HWV68_RS10300 2065427..2069032 - 3606 WP_004399367.1 membrane protein -
HWV68_RS10305 2069265..2069597 - 333 WP_026009814.1 hypothetical protein -
HWV68_RS10310 2069817..2069978 + 162 WP_120322743.1 putative holin-like toxin Toxin
- 2069959..2070132 - 174 - - Antitoxin
HWV68_RS10315 2070247..2071089 - 843 WP_003231327.1 hypothetical protein -
HWV68_RS10320 2071289..2071747 - 459 WP_003231326.1 type II toxin-antitoxin system antitoxin YobK -
HWV68_RS10325 2071757..2073559 - 1803 WP_004399481.1 type II toxin-antitoxin system toxin ribonuclease YobL -
HWV68_RS10330 2073661..2074218 - 558 WP_004399321.1 SMI1/KNR4 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2055871..2100354 44483


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(24-47)


Sequences

Toxin        


Download         Length: 54 a.a.        Molecular weight: 5780.74 Da        Isoelectric Point: 4.6641

>T166381 WP_120322743.1 NZ_CP058242:2069817-2069978 [Bacillus subtilis]
ISCTVSFAHSRESCSSPNERGDAMSTFQALMLMLAIGSFIIALLTYIEKIDLP

Download         Length: 162 bp

>T166381 NZ_CP074143:634984-635190 [Serratia sp. JSRIV002]
ATGCGCATCGAATGGGACGACGTTGCGTTGCAAGATCGGGAACGCATTTTTGAATTTCTTTATCCACTCAATTCATTGGC
CGCGGAACAAGTTGATGATGAGATTGAACTTGCCGTTGAGTCTCTGCTAGAAAACCCAGAAATGGGCAGGCTCACAAGCT
TAGCAAGCTTTGTTAGCGCACAATTATTCAATAATAAAAATATATAA

Antitoxin


Download         Length: 174 bp

>AT166381 NZ_CP058242:c2070132-2069959 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References