Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1931348..1931530 Replicon chromosome
Accession NZ_CP055225
Organism Staphylococcus aureus LAC

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag HUW68_RS09375 Protein ID WP_001801861.1
Coordinates 1931348..1931443 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1931471..1931530 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUW68_RS09335 1927008..1927634 + 627 Protein_1837 hypothetical protein -
HUW68_RS09340 1927675..1928019 + 345 WP_000627551.1 DUF3969 family protein -
HUW68_RS09345 1928117..1928668 + 552 WP_000414205.1 hypothetical protein -
HUW68_RS09350 1928886..1929527 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
HUW68_RS09355 1929641..1929826 - 186 WP_000809857.1 hypothetical protein -
HUW68_RS09360 1929828..1930004 - 177 WP_000375476.1 hypothetical protein -
HUW68_RS09365 1930015..1930398 - 384 WP_000070811.1 hypothetical protein -
HUW68_RS09370 1931002..1931145 - 144 WP_001549059.1 transposase -
HUW68_RS09375 1931348..1931443 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1931471..1931530 - 60 - - Antitoxin
HUW68_RS09380 1931566..1931667 + 102 WP_001791893.1 hypothetical protein -
HUW68_RS09385 1931645..1931821 - 177 Protein_1847 transposase -
HUW68_RS09390 1932015..1932392 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA 1924448..1964619 40171


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T162028 WP_001801861.1 NZ_CP055225:1931348-1931443 [Staphylococcus aureus LAC]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T162028 NZ_CP071490:c1059231-1058953 [Glaesserella parasuis]
ATGATTATTTCATTTAAGCATAAAGGATTGAAATTATTTTTTGAAACAGGATCAACCGCAGGTATTCAAGCAAATCACGC
TAGTAAACTTGCTTTTCAATTAGCCACTCTAAACCAAGCAAAAAGTGCTTTAGATATGAATGCACCTAGCTGGAATTTAC
ACCAATTACAAGATAATTTAGCTGGGCATTGGTCTATCAAGGTAAGTGGAAATTGGCGTTTAACTTTTAAATTTCAAAAT
GGTCACGCTGAAGTCGTGGACTATCAAGATTATCATTAA

Antitoxin


Download         Length: 60 bp

>AT162028 NZ_CP055225:c1931530-1931471 [Staphylococcus aureus LAC]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References