Detailed information of TA system TA158742

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): IasE-IsrA/SymE(toxin)
• Location: 740603..740821
• Replicon: chromosome
• Accession: NZ_CP054129
• Organism: Citrobacter portucalensis strain BY9F36

Toxin (Protein)

• Gene name: IasE
• Uniprot ID: -
• Locus tag: HRV88_RS03615
• Protein ID: WP_224759900.1
• Coordinates: 740603..740821 (+)
• Length: 73 a.a.

Antitoxin (RNA)

Gene name	IsrA
Locus tag	-
Coordinates	740725..740811 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HRV88_RS03585 (HRV88_03580)	736817..737692	-	876	WP_235126692.1	hypothetical protein	-
HRV88_RS03590 (HRV88_03585)	738230..738676	-	447	WP_100271913.1	type IV secretion protein Rhs	-
HRV88_RS03595 (HRV88_03590)	738673..739044	-	372	WP_235127576.1	polymorphic toxin type 47 domain-containing protein	-
HRV88_RS03600 (HRV88_03595)	739171..739482	+	312	WP_100271914.1	SymE family type I addiction module toxin	-
HRV88_RS03605 (HRV88_03600)	739552..739890	-	339	WP_235126694.1	hypothetical protein	-
HRV88_RS03610 (HRV88_03605)	739916..740380	-	465	WP_235127577.1	HNH endonuclease	-
HRV88_RS03615 (HRV88_03610)	740603..740821	+	219	WP_224759900.1	SymE family type I addiction module toxin	Toxin
-	740725..740811	-	87	-	-	Antitoxin
HRV88_RS03620 (HRV88_03615)	741126..741509	-	384	WP_212732922.1	hypothetical protein	-
HRV88_RS03625 (HRV88_03620)	741792..742238	-	447	WP_235126697.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	738729..751511	12782

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin SymE-like (10-40)

Sequences

Toxin

Protein

• Length: 73 a.a.
• Molecular weight: 8173.39 Da
• Isoelectric Point: 9.8826

>T158742 WP_224759900.1 NZ_CP054129:740603-740821 [Citrobacter portucalensis]
MRKTGMTTYYSQHPSLTLKGDWLREAGFETGKGVTVKISEVDEVRELRKELYLMKKSMNHVKAGVNNVVNGD

Nucleotide

• Length: 219 bp

>T158742 NZ_CP069798:1114650-1114976 [Paralysiella testudinis]
ATGAAGCGTGGTGACTTGATTACGGTTGCCATACAAGGTGACTATGGCAAACCCCGCCCGGCATTAGTGGTGCAGTCTGA
CGTTTTTGCCGGACACACAAGTATCTGCATATTGCCATTAACCTCAGATTTACACGAAGCACCATTATTCCGAATTTTAT
TGACGCCGAGCAGCAGTAATGGGTTGACCAAAAAATCACAGGTTATGGTGGATAAGATAATGACCATTCCGATTGCCAAG
GCAGGTGAAGTTATCGGTTCTCTGGATTATACGGCCATGCTGGAAATTGATCGCAGTATGGCCTTATTTTTAGGCATTGC
CAAATAA

Antitoxin

Nucleotide

• Length: 87 bp

>AT158742 NZ_CP054129:c740811-740725 [Citrobacter portucalensis]
TTCACCACATTATTTACCCCCGCCTTAACATGATTCATCGACTTTTTCATCAGATAAAGCTCCTTCCGTAGCTCCCTCAC
TTCGTCC

Structures

Antitoxin