156112

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrE-as-bsrE/-
Location 2069916..2070162 Replicon chromosome
Accession NZ_CP053102
Organism Bacillus subtilis subsp. subtilis str. 168

Toxin (Protein)


Gene name bsrE Uniprot ID -
Locus tag HIR77_RS22760 Protein ID WP_109789044.1
Coordinates 2069916..2070008 (+) Length 31 a.a.

Antitoxin (RNA)


Gene name as-bsrE
Locus tag -
Coordinates 2069989..2070162 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HIR77_RS10285 2065075..2065410 + 336 WP_009967409.1 hypothetical protein -
HIR77_RS10290 2065457..2069062 - 3606 WP_004399367.1 membrane protein -
HIR77_RS10295 2069295..2069627 - 333 WP_026009814.1 hypothetical protein -
HIR77_RS22760 2069916..2070008 + 93 WP_109789044.1 type I toxin-antitoxin system toxin BsrE Toxin
- 2069989..2070162 - 174 - - Antitoxin
HIR77_RS10305 2070277..2071119 - 843 WP_003231327.1 hypothetical protein -
HIR77_RS10310 2071319..2071777 - 459 WP_003231326.1 type II toxin-antitoxin system antitoxin YobK -
HIR77_RS10315 2071787..2073589 - 1803 WP_004399481.1 type II toxin-antitoxin system toxin ribonuclease YobL -
HIR77_RS10320 2073691..2074248 - 558 WP_004399321.1 SMI1/KNR4 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2055901..2100385 44484


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-24)


Sequences

Toxin        


Download         Length: 31 a.a.        Molecular weight: 3358.16 Da        Isoelectric Point: 4.1840

>T156112 WP_109789044.1 NZ_CP053102:2069916-2070008 [Bacillus subtilis subsp. subtilis str. 168]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Download         Length: 93 bp

>T156112 NZ_CP068827:3136086-3136397 [Escherichia coli]
ATGCTCTTCATCGAAACGGAAATTTTTACTGAAGATGTTCAAAAACTGCTGACCGACGATGAATTCAGTCGTTTTCAGTT
TTTCCTGGCCTTGAATCCTGACTATGGTGAGGTAATACCTGAAACTGGTGGGTTAAGAAAGGTTCGATGGGTGTCAGGAG
GAAAGGGGAAACGTGCTGGTGTCAGGGTTATTTACTTTCATCAGGTTAAACATTATGAGATCAGATTACTGCTTATTTAT
CGTAAGGGTATTAAAGATGATCTGTCTCCCCAGGAAAAAGCAATGCTCCGGTTGTTAAATACGAGGTGGTAA

Antitoxin


Download         Length: 174 bp

>AT156112 NZ_CP053102:c2070162-2069989 [Bacillus subtilis subsp. subtilis str. 168]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References