Detailed information of TA system TA154255

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 178433..178615
• Replicon: chromosome
• Accession: NZ_CP051483
• Organism: Staphylococcus aureus strain NGA66a

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: HGO94_RS01085
• Protein ID: WP_001801861.1
• Coordinates: 178520..178615 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	178433..178492 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HGO94_RS01070	177571..177948	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
HGO94_RS01075	178142..178318	+	177	Protein_175	transposase	-
HGO94_RS01080	178296..178397	-	102	WP_001791893.1	hypothetical protein	-
-	178433..178492	+	60	-	-	Antitoxin
HGO94_RS01085	178520..178615	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
HGO94_RS01090	178818..178961	+	144	WP_001549059.1	transposase	-
HGO94_RS01095	179565..179948	+	384	WP_000070811.1	hypothetical protein	-
HGO94_RS01100	179959..180135	+	177	WP_000375477.1	hypothetical protein	-
HGO94_RS01105	180153..180323	+	171	WP_169301139.1	hypothetical protein	-
HGO94_RS01110	180438..181066	+	629	Protein_182	ImmA/IrrE family metallo-endopeptidase	-
HGO94_RS01115	181264..181836	-	573	WP_000414202.1	hypothetical protein	-
HGO94_RS01120	181937..182278	-	342	WP_000627541.1	DUF3969 family protein	-
HGO94_RS01125	182319..182945	-	627	WP_000669017.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	Similar MGE(s) Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE. Detail Genome accession Organism MGE type Related TA Coordinates Mash distance View NC_009641 Staphylococcus aureus subsp. aureus str. Newman Prophage TA010024 1882747..1922929 0.007	inside	Prophage	-	hlgA / lukD	145330..185503	40173

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T154255 WP_001801861.1 NZ_CP051483:c178615-178520 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T154255 NZ_CP067426:c710148-709684 [Escherichia coli O22:H8]
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGACGCTTTAGTTGC
CGAAGTCGAGACATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCCGCCACAAAGTTATTGGCGGTAGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGTTATCGTCTCTTCTTTCGTTATAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACTCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGCAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAACCCTCACCCGAGAGACAGAAGAAACCCATTGA

Antitoxin

Nucleotide

• Length: 60 bp

>AT154255 NZ_CP051483:178433-178492 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin