Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) bsrE-as-bsrE/-
Location 3610693..3610939 Replicon chromosome
Accession NZ_CP047325
Organism Bacillus subtilis strain GOT9

Toxin (Protein)


Gene name bsrE Uniprot ID -
Locus tag GSY53_RS21330 Protein ID WP_109789044.1
Coordinates 3610693..3610785 (+) Length 31 a.a.

Antitoxin (RNA)


Gene name as-bsrE
Locus tag -
Coordinates 3610766..3610939 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GSY53_RS18245 3605852..3606187 + 336 WP_009967409.1 hypothetical protein -
GSY53_RS18250 3606234..3609839 - 3606 WP_004399367.1 membrane protein -
GSY53_RS18255 3610072..3610404 - 333 WP_026009814.1 hypothetical protein -
GSY53_RS21330 3610693..3610785 + 93 WP_109789044.1 type I toxin-antitoxin system toxin BsrE Toxin
- 3610766..3610939 - 174 - - Antitoxin
GSY53_RS18265 3611054..3611896 - 843 WP_003231327.1 hypothetical protein -
GSY53_RS18270 3612096..3612554 - 459 WP_003231326.1 type II toxin-antitoxin system antitoxin YobK -
GSY53_RS18275 3612564..3614366 - 1803 WP_004399481.1 type II toxin-antitoxin system toxin ribonuclease YobL -
GSY53_RS18280 3614468..3615025 - 558 WP_004399321.1 SMI1/KNR4 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 3596678..3630044 33366


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(1-24)


Sequences

Toxin        


Download         Length: 31 a.a.        Molecular weight: 3358.16 Da        Isoelectric Point: 4.1840

>T145975 WP_109789044.1 NZ_CP047325:3610693-3610785 [Bacillus subtilis]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Download         Length: 93 bp

>T145975 NZ_CP062713:c4711975-4711661 [Escherichia coli O157:H7]
ATGCAATTTACGGTATACCGCAGTCGCAGTAGGAACGCCGCGTTTCCCTTTGTTATCGATGTTACCAGCGACATTATTGG
TGTGATTAATCGCCGTATTGTTATTCCATTAACACCTATTGAACGATTTAGCCGTATTCGCCCACCAGAACGGCTTAACC
CAATCCTTTTACTGGTAGACGGCAAAGAATATGTGCTCATGACGCATGAGACTGCAACTGTTCCAGTTAACGCGCTGGGA
ACGAAATTTTGCGATGCCAGCGCGCACCGAACGTTGATTAAAGGAGCATTAGATTTTATGCTCGACGGGATTTAA

Antitoxin


Download         Length: 174 bp

>AT145975 NZ_CP047325:c3610939-3610766 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References