Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) fst-RNAII/-
Location 2879120..2879314 Replicon chromosome
Accession NZ_CP046111
Organism Enterococcus faecalis strain 111540047-1

Toxin (Protein)


Gene name fst Uniprot ID -
Locus tag GKQ56_RS13955 Protein ID WP_015543884.1
Coordinates 2879120..2879215 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name RNAII
Locus tag -
Coordinates 2879250..2879314 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GKQ56_RS13940 2875481..2876635 - 1155 WP_002355280.1 mannitol-1-phosphate 5-dehydrogenase -
GKQ56_RS13945 2876650..2877087 - 438 WP_002355279.1 PTS sugar transporter subunit IIA -
GKQ56_RS13950 2877102..2878874 - 1773 WP_002387897.1 PTS mannitol transporter subunit IICBA -
GKQ56_RS13955 2879120..2879215 + 96 WP_015543884.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2879250..2879314 - 65 NuclAT_14 - Antitoxin
GKQ56_RS13960 2879473..2879907 - 435 WP_002355276.1 PTS sugar transporter subunit IIA -
GKQ56_RS13965 2879918..2881951 - 2034 WP_002355275.1 transcription antiterminator -
GKQ56_RS13970 2881942..2883690 - 1749 WP_002403688.1 PTS transporter subunit EIIC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
flank IS/Tn - - 2874549..2875352 803


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3659.47 Da        Isoelectric Point: 4.6275

>T143572 WP_015543884.1 NZ_CP046111:2879120-2879215 [Enterococcus faecalis]
MYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Download         Length: 96 bp

>T143572 NZ_CP061206:2314212-2314319 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTCTGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 65 bp

>AT143572 NZ_CP046111:c2879314-2879250 [Enterococcus faecalis]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGCGGTAGGGTGTCTTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References