Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1858814..1858996 Replicon chromosome
Accession NZ_CP038229
Organism Staphylococcus aureus strain MJ163

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag E4J95_RS08910 Protein ID WP_001801861.1
Coordinates 1858814..1858909 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1858937..1858996 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
E4J95_RS08875 1854484..1855110 + 627 WP_045177256.1 hypothetical protein -
E4J95_RS08880 1855151..1855492 + 342 WP_045177258.1 DUF3969 family protein -
E4J95_RS08885 1855593..1856165 + 573 WP_045177260.1 hypothetical protein -
E4J95_RS08890 1856363..1856920 - 558 WP_045177261.1 ImmA/IrrE family metallo-endopeptidase -
E4J95_RS08895 1857294..1857470 - 177 WP_000375477.1 hypothetical protein -
E4J95_RS08900 1857481..1857864 - 384 WP_000070811.1 hypothetical protein -
E4J95_RS08905 1858468..1858611 - 144 WP_001549059.1 transposase -
E4J95_RS08910 1858814..1858909 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1858937..1858996 - 60 - - Antitoxin
E4J95_RS08915 1859032..1859133 + 102 WP_001791893.1 hypothetical protein -
E4J95_RS08920 1859111..1859287 - 177 Protein_1754 transposase -
E4J95_RS08925 1859481..1859858 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA 1851924..1891841 39917


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T120832 WP_001801861.1 NZ_CP038229:1858814-1858909 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T120832 NZ_CP038229:1858814-1858909 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT120832 NZ_CP038229:c1858996-1858937 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References