Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) bsrE-as-bsrE/-
Location 2050759..2051005 Replicon chromosome
Accession NZ_CP035394
Organism Bacillus subtilis strain SRCM103696

Toxin (Protein)


Gene name bsrE Uniprot ID -
Locus tag ES967_RS21075 Protein ID WP_109789044.1
Coordinates 2050759..2050851 (+) Length 31 a.a.

Antitoxin (RNA)


Gene name as-bsrE
Locus tag -
Coordinates 2050832..2051005 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ES967_RS10295 2045918..2046253 + 336 WP_009967409.1 hypothetical protein -
ES967_RS10300 2046300..2049905 - 3606 WP_004399367.1 membrane protein -
ES967_RS10305 2050138..2050470 - 333 WP_026009814.1 hypothetical protein -
ES967_RS21075 2050759..2050851 + 93 WP_109789044.1 type I toxin-antitoxin system toxin BsrE Toxin
- 2050832..2051005 - 174 - - Antitoxin
ES967_RS10315 2051120..2051962 - 843 WP_003231327.1 hypothetical protein -
ES967_RS10320 2052162..2052620 - 459 WP_003231326.1 type II toxin-antitoxin system antitoxin YobK -
ES967_RS10325 2052630..2054432 - 1803 WP_128992278.1 type II toxin-antitoxin system toxin ribonuclease YobL -
ES967_RS10330 2054534..2055091 - 558 WP_004399321.1 SMI1/KNR4 family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - - 2036744..2070109 33365


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-24)


Sequences


Toxin        


Download         Length: 31 a.a.        Molecular weight: 3358.16 Da        Isoelectric Point: 4.1840

>T117738 WP_109789044.1 NZ_CP035394:2050759-2050851 [Bacillus subtilis]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Download         Length: 93 bp

>T117738 NZ_CP035394:2050759-2050851 [Bacillus subtilis]
ATGTCAACATTCCAGGCATTAATGCTAATGCTTGCAATCGGGTCGTTTATAATCGCCCTATTGACGTATATAGAAAAAAT
AGACCTCCCTTGA

Antitoxin


Download         Length: 174 bp

>AT117738 NZ_CP035394:c2051005-2050832 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References