Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1847449..1847631 Replicon chromosome
Accession NZ_CP031664
Organism Staphylococcus aureus strain 28

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag DD545_RS09320 Protein ID WP_001801861.1
Coordinates 1847449..1847544 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1847572..1847631 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DD545_RS09270 1843109..1843735 + 627 WP_000669046.1 hypothetical protein -
DD545_RS09275 1843776..1844120 + 345 WP_000627551.1 DUF3969 family protein -
DD545_RS09280 1844218..1844769 + 552 WP_000414205.1 hypothetical protein -
DD545_RS09285 1844987..1845628 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
DD545_RS09290 1845742..1845927 - 186 WP_000809857.1 hypothetical protein -
DD545_RS09295 1845929..1846105 - 177 WP_000375476.1 hypothetical protein -
DD545_RS09300 1846116..1846499 - 384 WP_000070811.1 hypothetical protein -
DD545_RS09310 1847103..1847246 - 144 WP_001549059.1 transposase -
DD545_RS09320 1847449..1847544 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1847572..1847631 - 60 - - Antitoxin
DD545_RS09325 1847667..1847768 + 102 WP_001791893.1 hypothetical protein -
DD545_RS09330 1847746..1847922 - 177 Protein_1758 transposase -
DD545_RS09335 1848116..1848493 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA 1840549..1880719 40170


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T109684 WP_001801861.1 NZ_CP031664:1847449-1847544 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T109684 NZ_CP031664:1847449-1847544 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT109684 NZ_CP031664:c1847631-1847572 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References