108794

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1830232..1830414 Replicon chromosome
Accession NZ_CP031265
Organism Staphylococcus aureus strain 13

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag DWB87_RS09095 Protein ID WP_001801861.1
Coordinates 1830232..1830327 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1830355..1830414 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DWB87_RS09045 1825902..1826528 + 627 WP_000669017.1 hypothetical protein -
DWB87_RS09050 1826569..1826910 + 342 WP_000627541.1 DUF3969 family protein -
DWB87_RS09055 1827011..1827583 + 573 WP_000414202.1 hypothetical protein -
DWB87_RS09060 1827781..1828338 - 558 Protein_1736 ImmA/IrrE family metallo-endopeptidase -
DWB87_RS09065 1828524..1828694 - 171 WP_169301139.1 hypothetical protein -
DWB87_RS09070 1828712..1828888 - 177 WP_000375477.1 hypothetical protein -
DWB87_RS09075 1828899..1829282 - 384 WP_000070811.1 hypothetical protein -
DWB87_RS09085 1829886..1830029 - 144 WP_001549059.1 transposase -
DWB87_RS09095 1830232..1830327 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1830355..1830414 - 60 - - Antitoxin
DWB87_RS09100 1830450..1830551 + 102 WP_001791893.1 hypothetical protein -
DWB87_RS09105 1830529..1830705 - 177 Protein_1743 transposase -
DWB87_RS09110 1830899..1831276 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA 1823512..1863510 39998


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T108794 WP_001801861.1 NZ_CP031265:1830232-1830327 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T108794 NZ_CP031265:1830232-1830327 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT108794 NZ_CP031265:c1830414-1830355 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References