Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1977493..1977675 Replicon chromosome
Accession NZ_CP029678
Organism Staphylococcus aureus strain AR_0216

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag CSB72_RS10380 Protein ID WP_001801861.1
Coordinates 1977493..1977588 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1977616..1977675 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSB72_RS10330 1973153..1973779 + 627 Protein_1909 hypothetical protein -
CSB72_RS10335 1973820..1974164 + 345 WP_000627551.1 DUF3969 family protein -
CSB72_RS10340 1974262..1974813 + 552 WP_000414205.1 hypothetical protein -
CSB72_RS10345 1975031..1975672 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
CSB72_RS10350 1975786..1975971 - 186 WP_000809857.1 hypothetical protein -
CSB72_RS10355 1975973..1976149 - 177 WP_000375476.1 hypothetical protein -
CSB72_RS10360 1976160..1976543 - 384 WP_000070811.1 hypothetical protein -
CSB72_RS10370 1977147..1977290 - 144 WP_001549059.1 transposase -
CSB72_RS10380 1977493..1977588 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1977616..1977675 - 60 - - Antitoxin
CSB72_RS10385 1977711..1977812 + 102 WP_001791893.1 hypothetical protein -
CSB72_RS10390 1977790..1977966 - 177 Protein_1919 transposase -
CSB72_RS10395 1978160..1978537 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA 1970593..2010764 40171


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T106287 WP_001801861.1 NZ_CP029678:1977493-1977588 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T106287 NZ_CP029678:1977493-1977588 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT106287 NZ_CP029678:c1977675-1977616 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References