Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 768179..768361 Replicon chromosome
Accession NZ_CP029664
Organism Staphylococcus aureus strain AR_0226

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag CSB82_RS04410 Protein ID WP_001801861.1
Coordinates 768266..768361 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 768179..768238 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSB82_RS04395 767317..767694 + 378 WP_001037045.1 DUF1433 domain-containing protein -
CSB82_RS04400 767888..768064 + 177 Protein_779 transposase -
CSB82_RS04405 768042..768143 - 102 WP_001791893.1 hypothetical protein -
- 768179..768238 + 60 - - Antitoxin
CSB82_RS04410 768266..768361 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
CSB82_RS04420 768564..768707 + 144 WP_001549059.1 transposase -
CSB82_RS04430 769311..769694 + 384 WP_000070811.1 hypothetical protein -
CSB82_RS04435 769705..769881 + 177 WP_000375476.1 hypothetical protein -
CSB82_RS04440 769883..770068 + 186 WP_000809857.1 hypothetical protein -
CSB82_RS04445 770182..770823 + 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
CSB82_RS04450 771041..771592 - 552 WP_000414205.1 hypothetical protein -
CSB82_RS04455 771690..772034 - 345 WP_000627551.1 DUF3969 family protein -
CSB82_RS04460 772075..772701 - 627 Protein_789 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - hlgA / lukD 735090..775261 40171


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T106198 WP_001801861.1 NZ_CP029664:c768361-768266 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T106198 NZ_CP029664:c768361-768266 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT106198 NZ_CP029664:768179-768238 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References