Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1929117..1929299 Replicon chromosome
Accession NZ_CP029031
Organism Staphylococcus aureus strain CIT

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag DDG67_RS09795 Protein ID WP_001801861.1
Coordinates 1929117..1929212 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1929240..1929299 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DDG67_RS09745 1924777..1925403 + 627 Protein_1841 hypothetical protein -
DDG67_RS09750 1925444..1925788 + 345 WP_000627551.1 DUF3969 family protein -
DDG67_RS09755 1925886..1926437 + 552 WP_000414205.1 hypothetical protein -
DDG67_RS09760 1926655..1927296 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
DDG67_RS09765 1927410..1927595 - 186 WP_000809857.1 hypothetical protein -
DDG67_RS09770 1927597..1927773 - 177 WP_000375476.1 hypothetical protein -
DDG67_RS09775 1927784..1928167 - 384 WP_000070811.1 hypothetical protein -
DDG67_RS09785 1928771..1928914 - 144 WP_001549059.1 transposase -
DDG67_RS09795 1929117..1929212 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1929240..1929299 - 60 - - Antitoxin
DDG67_RS09800 1929335..1929436 + 102 WP_001791893.1 hypothetical protein -
DDG67_RS09805 1929414..1929590 - 177 Protein_1851 transposase -
DDG67_RS09810 1929784..1930161 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA 1922217..1962388 40171


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T104602 WP_001801861.1 NZ_CP029031:1929117-1929212 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T104602 NZ_CP029031:1929117-1929212 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 60 bp

>AT104602 NZ_CP029031:c1929299-1929240 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References