Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | ralRA/- |
Location | 2757929..2758300 | Replicon | chromosome |
Accession | NZ_CP028650 | ||
Organism | Escherichia coli strain 124 |
Toxin (Protein)
Gene name | ralR | Uniprot ID | A0A0D6ZRD3 |
Locus tag | C9E53_RS14425 | Protein ID | WP_001443846.1 |
Coordinates | 2758151..2758300 (-) | Length | 50 a.a. |
Antitoxin (RNA)
Gene name | ralA | ||
Locus tag | - | ||
Coordinates | 2757929..2758107 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
C9E53_RS28390 | 2753681..2753851 | + | 171 | WP_001625136.1 | hypothetical protein | - |
C9E53_RS14400 | 2753884..2755257 | + | 1374 | WP_000123746.1 | ATP-dependent RNA helicase DbpA | - |
C9E53_RS14405 | 2755386..2756321 | - | 936 | WP_001157407.1 | tRNA 2-thiocytidine(32) synthetase TtcA | - |
C9E53_RS14410 | 2756373..2757608 | - | 1236 | WP_000040839.1 | site-specific integrase | - |
C9E53_RS14415 | 2757610..2757825 | - | 216 | WP_000079604.1 | excisionase XisR | - |
C9E53_RS14420 | 2757925..2758113 | - | 189 | WP_001302840.1 | DUF1187 family protein | - |
- | 2757929..2758107 | + | 179 | NuclAT_0 | - | Antitoxin |
- | 2757929..2758107 | + | 179 | NuclAT_0 | - | Antitoxin |
- | 2757929..2758107 | + | 179 | NuclAT_0 | - | Antitoxin |
- | 2757929..2758107 | + | 179 | NuclAT_0 | - | Antitoxin |
C9E53_RS14425 | 2758151..2758300 | - | 150 | WP_001443846.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | Toxin |
C9E53_RS14430 | 2758356..2759165 | - | 810 | WP_000166313.1 | recombination protein RecT | - |
C9E53_RS14435 | 2759158..2761758 | - | 2601 | WP_000105140.1 | exodeoxyribonuclease VIII | - |
C9E53_RS14440 | 2761860..2762135 | - | 276 | WP_001344816.1 | hypothetical protein | - |
C9E53_RS14445 | 2762210..2762380 | - | 171 | WP_001352098.1 | conserved protein, Rac prophage | - |
C9E53_RS14450 | 2762380..2762601 | - | 222 | WP_000560223.1 | killing protein KilR | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
inside | Prophage | - | - | 2744122..2805525 | 61403 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 50 a.a. Molecular weight: 5383.12 Da Isoelectric Point: 8.3398
>T102264 WP_001443846.1 NZ_CP028650:c2758300-2758151 [Escherichia coli]
MRYDNVKPCPFCGCPSVTVKAISGYYRAKCNGCESRTGYGGSEKEALER
MRYDNVKPCPFCGCPSVTVKAISGYYRAKCNGCESRTGYGGSEKEALER
Download Length: 150 bp
>T102264 NZ_CP028650:c2758300-2758151 [Escherichia coli]
ATGAGATATGACAATGTTAAACCATGTCCATTTTGTGGTTGTCCATCAGTAACGGTGAAAGCCATTTCAGGATATTACCG
AGCGAAGTGTAACGGATGCGAATCCCGAACCGGTTATGGTGGAAGTGAAAAAGAAGCACTCGAACGATGA
ATGAGATATGACAATGTTAAACCATGTCCATTTTGTGGTTGTCCATCAGTAACGGTGAAAGCCATTTCAGGATATTACCG
AGCGAAGTGTAACGGATGCGAATCCCGAACCGGTTATGGTGGAAGTGAAAAAGAAGCACTCGAACGATGA
Antitoxin
Download Length: 179 bp
>AT102264 NZ_CP028650:2757929-2758107 [Escherichia coli]
GAGGACTGAAGTTTCTCGCAATTAAAATTTATCAGTTTTACTTTCTGCTCTCTGGAAACGCCTGCTTCTTTTTTACCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAGTTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTGCCACCTTCCTTTT
CAATAGTGGCGGTAATTTT
GAGGACTGAAGTTTCTCGCAATTAAAATTTATCAGTTTTACTTTCTGCTCTCTGGAAACGCCTGCTTCTTTTTTACCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAGTTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTGCCACCTTCCTTTT
CAATAGTGGCGGTAATTTT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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