MGE detailed information
MGE type: Conjugative plasmid MGE length: 107837 bp
Accession: NZ_OW967967 Location: 1..107837 Organism: Escherichia coli isolate 648 Replicon: plasmid P1
Accession: NZ_OW967967 Location: 1..107837 Organism: Escherichia coli isolate 648 Replicon: plasmid P1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LQ127_RS24915 (AI2858V1_4833) | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| LQ127_RS24920 (AI2858V1_4835) | 1263..2003 | - | 741 | WP_001066953.1 | tyrosine-type recombinase/integrase | - |
| LQ127_RS24925 | 2124..2306 | - | 183 | WP_042344623.1 | hypothetical protein | - |
| LQ127_RS24930 | 2373..2662 | - | 290 | Protein_3 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| LQ127_RS24935 (AI2858V1_4837) | 2649..2917 | - | 269 | Protein_4 | type II toxin-antitoxin system ParD family antitoxin | - |
| LQ127_RS24940 (AI2858V1_4838) | 3449..4618 | + | 1170 | WP_001072355.1 | hypothetical protein | - |
| LQ127_RS24945 (AI2858V1_REPA000000280) | 4651..4779 | + | 129 | Protein_6 | IS481 family transposase | - |
| LQ127_RS24950 | 4814..5002 | - | 189 | Protein_7 | hypothetical protein | - |
| LQ127_RS24955 (AI2858V1_REPA000000271) | 5050..5747 | + | 698 | WP_095033700.1 | IS1 family transposase IS1R | Transposase |
| LQ127_RS24960 | 5763..5882 | + | 120 | Protein_9 | transcriptional regulator | - |
| LQ127_RS24965 (AI2858V1_4841) | 5860..6483 | - | 624 | WP_000088605.1 | Tetracycline repressor protein class B from transposon Tn10 | VF |
| LQ127_RS24970 (AI2858V1_4842) | 6565..7770 | + | 1206 | WP_001089068.1 | Tetracycline resistance protein, class B | ARG |
| LQ127_RS24975 (AI2858V1_4843) | 7883..8476 | - | 594 | WP_000428546.1 | tetracyline resistance-associated transcriptional repressor TetC | - |
| LQ127_RS24980 (AI2858V1_4844) | 8564..8980 | + | 417 | WP_000275180.1 | Transposon Tn10 TetD protein | VF |
| LQ127_RS24985 (AI2858V1_REPA000000238) | 8990..9142 | - | 153 | Protein_14 | IS4 family transposase IS10R | Transposase |
| LQ127_RS24990 (AI2858V1_4845) | 9188..9892 | + | 705 | WP_001067858.1 | IS4 family transposase IS10R | Transposase |
| LQ127_RS24995 (AI2858V1_4846) | 10014..10718 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| LQ127_RS25000 (AI2858V1_5035) | 10956..11786 | - | 831 | WP_001334766.1 | Beta-lactamase OXA-1 | ARG |
| LQ127_RS25005 (AI2858V1_4848) | 11917..12471 | - | 555 | WP_063840321.1 | Aminoglycoside N(6')-acetyltransferase type 1 | ARG |
| LQ127_RS25010 (AI2858V1_4849) | 12615..13319 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| LQ127_RS25015 (AI2858V1_4850) | 13384..14064 | - | 681 | Protein_20 | class 1 integron integrase IntI1 | - |
| LQ127_RS25020 (AI2858V1_4851) | 14222..14695 | + | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| LQ127_RS25025 (AI2858V1_4852) | 14826..15614 | + | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| LQ127_RS25030 (AI2858V1_4853) | 15820..16167 | + | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| LQ127_RS25035 (AI2858V1_4854) | 16161..17000 | + | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| LQ127_RS25040 (AI2858V1_4855) | 17128..17628 | + | 501 | WP_000376623.1 | GNAT family N-acetyltransferase | - |
| LQ127_RS25045 | 17949..18017 | + | 69 | Protein_26 | EAL domain-containing protein | - |
| LQ127_RS25050 (AI2858V1_4856) | 18135..18899 | + | 765 | WP_001389365.1 | IS6-like element IS6100 family transposase | - |
| LQ127_RS25055 (AI2858V1_4857) | 19101..19937 | - | 837 | WP_000480968.1 | hypothetical protein | ARG |
| LQ127_RS25060 (AI2858V1_4858) | 19937..20740 | - | 804 | WP_001082319.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| LQ127_RS25065 (AI2858V1_4859) | 20752..21420 | - | 669 | WP_023434504.1 | Tn3 family transposase TnpR_ISMex22 | Transposase |
| LQ127_RS25070 (AI2858V1_4860) | 21546..24431 | + | 2886 | WP_006473469.1 | Tn3 family transposase TnpA_ISRsp12 | Transposase |
| LQ127_RS25075 (AI2858V1_4861) | 24465..25178 | + | 714 | Protein_32 | IS21 family transposase | - |
| LQ127_RS25080 (AI2858V1_4862) | 25175..25933 | + | 759 | WP_024946713.1 | IS21-like element helper ATPase IstB | - |
| LQ127_RS25085 (AI2858V1_4863) | 26144..26776 | - | 633 | WP_024946712.1 | OsmC family protein | - |
| LQ127_RS25090 (AI2858V1_4864) | 26974..27708 | - | 735 | WP_033878928.1 | IS21-like element helper ATPase IstB | - |
| LQ127_RS25095 (AI2858V1_4865) | 27641..29207 | - | 1567 | Protein_36 | IS21 family transposase | - |
| LQ127_RS25100 (AI2858V1_4866) | 29350..32352 | + | 3003 | WP_024946709.1 | Tn3 family transposase | - |
| LQ127_RS25105 | 32411..32551 | + | 141 | Protein_38 | hypothetical protein | - |
| LQ127_RS25110 | 32603..32974 | + | 372 | Protein_39 | phosphotransferase | - |
| LQ127_RS25115 (AI2858V1_4868) | 32974..33810 | + | 837 | WP_000480968.1 | hypothetical protein | ARG |
| LQ127_RS25120 (AI2858V1_REPA000000274) | 33917..34147 | + | 231 | Protein_41 | IS6 family transposase | - |
| LQ127_RS25125 (AI2858V1_4870) | 34640..35224 | - | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| LQ127_RS25130 (AI2858V1_4871) | 35224..36462 | - | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| LQ127_RS25135 (AI2858V1_4872) | 36459..37373 | - | 915 | WP_023063803.1 | hypothetical protein | ARG |
| LQ127_RS25140 (AI2858V1_4873) | 37495..38199 | - | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| LQ127_RS25145 (AI2858V1_4874) | 38334..38429 | + | 96 | WP_013362819.1 | 23S rRNA methyltransferase attenuation leader peptide | - |
| LQ127_RS25150 (AI2858V1_4875) | 38555..39292 | + | 738 | WP_013362818.1 | rRNA adenine N-6-methyltransferase | ARG |
| LQ127_RS25155 (AI2858V1_4877) | 39922..40371 | + | 450 | WP_013362817.1 | hypothetical protein | - |
| LQ127_RS25160 (AI2858V1_4878) | 40332..40673 | + | 342 | WP_023909256.1 | 60 kDa chaperonin | VF |
| LQ127_RS25165 (AI2858V1_4879) | 40948..42339 | + | 1392 | Protein_50 | IS91 family transposase | - |
| LQ127_RS25170 (AI2858V1_4880) | 42393..43097 | + | 705 | WP_001067855.1 | IS6-like element IS26 family transposase | - |
| LQ127_RS25175 (AI2858V1_4881) | 43163..43708 | + | 546 | Protein_52 | Tn3 family transposase TnpA_Tn3 | Transposase |
| LQ127_RS25180 (AI2858V1_REPA000000272) | 43744..44159 | - | 416 | Protein_53 | IS1-like element IS1B family transposase | - |
| LQ127_RS25185 (AI2858V1_4883) | 44408..44809 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| LQ127_RS25190 (AI2858V1_4884) | 44742..44999 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| LQ127_RS25195 (AI2858V1_4885) | 45092..45745 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| LQ127_RS25200 (AI2858V1_4886) | 46684..47541 | - | 858 | WP_000130646.1 | incFII family plasmid replication initiator RepA | - |
| LQ127_RS25205 | 47534..47608 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| LQ127_RS25210 (AI2858V1_4887) | 47846..48100 | - | 255 | WP_000083830.1 | replication regulatory protein RepA | - |
| LQ127_RS25215 (AI2858V1_4888) | 48340..48930 | - | 591 | WP_000766807.1 | DUF2726 domain-containing protein | - |
| LQ127_RS25220 (AI2858V1_4889) | 48968..49177 | - | 210 | WP_001298565.1 | hemolysin expression modulator Hha | - |
| LQ127_RS25225 (AI2858V1_4890) | 49223..49684 | - | 462 | WP_001233838.1 | thermonuclease family protein | - |
| LQ127_RS25230 | 49929..50141 | - | 213 | WP_001309245.1 | ANR family transcriptional regulator | - |
| LQ127_RS25235 (AI2858V1_4891) | 50270..50830 | - | 561 | WP_000139323.1 | fertility inhibition protein FinO | - |
| LQ127_RS25240 (AI2858V1_4892) | 50933..51793 | - | 861 | WP_000704523.1 | Quorum-quenching protein AidA | VF |
| LQ127_RS25245 (AI2858V1_4893) | 51852..52598 | - | 747 | WP_000205725.1 | conjugal transfer pilus acetylase TraX | - |
| LQ127_RS25250 (AI2858V1_4894) | 52618..57888 | - | 5271 | WP_032153768.1 | Multifunctional conjugation protein TraI | Relaxase |
| LQ127_RS25255 (AI2858V1_4895) | 57888..60086 | - | 2199 | WP_024623315.1 | type IV conjugative transfer system coupling protein TraD | - |
| LQ127_RS25260 (AI2858V1_4896) | 60083..60862 | - | 780 | WP_000199914.1 | hypothetical protein | - |
| LQ127_RS25265 (AI2858V1_4897) | 61065..61796 | - | 732 | WP_000850429.1 | conjugal transfer complement resistance protein TraT | - |
| LQ127_RS25270 (AI2858V1_4898) | 61828..62325 | - | 498 | WP_000605862.1 | entry exclusion protein | - |
| LQ127_RS25275 (AI2858V1_4899) | 62344..65163 | - | 2820 | WP_001007062.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| LQ127_RS25280 (AI2858V1_4900) | 65160..66533 | - | 1374 | WP_000944328.1 | conjugal transfer pilus assembly protein TraH | - |
| LQ127_RS25285 (AI2858V1_4901) | 66520..66912 | - | 393 | WP_000659962.1 | F-type conjugal transfer protein TrbF | - |
| LQ127_RS25290 (AI2858V1_4902) | 66893..67240 | - | 348 | WP_071571857.1 | P-type conjugative transfer protein TrbJ | - |
| LQ127_RS25295 (AI2858V1_4903) | 67170..67715 | - | 546 | WP_000059829.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| LQ127_RS25300 (AI2858V1_4904) | 67702..67986 | - | 285 | WP_001617873.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| LQ127_RS25305 | 68113..68433 | - | 321 | WP_001348757.1 | conjugal transfer protein TrbA | - |
| LQ127_RS25315 (AI2858V1_4907) | 69234..69434 | - | 201 | Protein_80 | hypothetical protein | - |
| LQ127_RS25320 (AI2858V1_4908) | 69421..69987 | - | 567 | WP_000399791.1 | type IV conjugative transfer system protein TraE | - |
| LQ127_RS25325 (AI2858V1_4909) | 70009..70320 | - | 312 | WP_000012107.1 | type IV conjugative transfer system protein TraL | - |
| LQ127_RS25330 (AI2858V1_4910) | 70325..70687 | - | 363 | WP_000338606.1 | type IV conjugative transfer system pilin TraA | - |
| LQ127_RS25335 (AI2858V1_4911) | 70721..70948 | - | 228 | WP_001254388.1 | conjugal transfer relaxosome protein TraY | - |
| LQ127_RS25340 (AI2858V1_4912) | 71036..71713 | - | 678 | WP_001348626.1 | PAS domain-containing protein | - |
| LQ127_RS25345 (AI2858V1_4913) | 71847..72230 | - | 384 | WP_001151566.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| LQ127_RS25350 (AI2858V1_4914) | 72573..73163 | + | 591 | WP_001376243.1 | hypothetical protein | VF |
| LQ127_RS25355 (AI2858V1_4915) | 73460..74281 | - | 822 | WP_001234469.1 | DUF932 domain-containing protein | - |
| LQ127_RS25360 (AI2858V1_4916) | 74400..74687 | - | 288 | WP_000107535.1 | hypothetical protein | - |
| LQ127_RS25365 | 74712..74918 | - | 207 | WP_000275859.1 | hypothetical protein | - |
| LQ127_RS25370 (AI2858V1_4917) | 75528..75719 | - | 192 | WP_001027516.1 | hypothetical protein | - |
| LQ127_RS25375 (AI2858V1_4918) | 75716..76138 | - | 423 | WP_000271753.1 | DUF1380 family protein | - |
| LQ127_RS25380 (AI2858V1_4919) | 76185..76610 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| LQ127_RS25385 (AI2858V1_4920) | 77027..77803 | - | 777 | WP_001753849.1 | hypothetical protein | - |
| LQ127_RS25390 (AI2858V1_4921) | 77854..78372 | - | 519 | WP_123325260.1 | DUF1380 family protein | - |
| LQ127_RS25395 (AI2858V1_4922) | 78302..78523 | - | 222 | WP_001104873.1 | hypothetical protein | - |
| LQ127_RS25400 (AI2858V1_4923) | 78524..79207 | - | 684 | WP_000086185.1 | DNA methylase | - |
| LQ127_RS25405 | 79284..79595 | - | 312 | WP_011254640.1 | hypothetical protein | - |
| LQ127_RS25410 (AI2858V1_4924) | 79592..80494 | - | 903 | WP_001348615.1 | DUF1281 domain-containing protein | - |
| LQ127_RS25415 (AI2858V1_4925) | 81361..82332 | - | 972 | WP_000817036.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| LQ127_RS25420 (AI2858V1_4926) | 82332..83498 | - | 1167 | WP_000772446.1 | hypothetical protein | VF |
| LQ127_RS25425 (AI2858V1_4927) | 84086..84841 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| LQ127_RS25430 (AI2858V1_4928) | 85615..86421 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| LQ127_RS25435 (AI2858V1_4929) | 86422..86727 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| LQ127_RS25440 (AI2858V1_4930) | 86729..86947 | - | 219 | WP_023909027.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| LQ127_RS25445 (AI2858V1_4931) | 87581..87778 | + | 198 | WP_000215657.1 | hypothetical protein | - |
| LQ127_RS25450 (AI2858V1_4932) | 87775..88059 | - | 285 | WP_000642771.1 | hypothetical protein | - |
| LQ127_RS25455 (AI2858V1_4933) | 88079..89212 | - | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| LQ127_RS25460 (AI2858V1_4934) | 89475..92594 | - | 3120 | WP_023909028.1 | hypothetical protein | - |
| LQ127_RS25465 (AI2858V1_4935) | 92901..93131 | + | 231 | WP_001261287.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin Detail |
| LQ127_RS25470 (AI2858V1_4936) | 93128..93544 | + | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| LQ127_RS25475 (AI2858V1_4937) | 93706..95844 | - | 2139 | WP_000350635.1 | AAA family ATPase | - |
| LQ127_RS25480 (AI2858V1_4938) | 96309..97304 | + | 996 | WP_000246636.1 | hypothetical protein | - |
| LQ127_RS25485 (AI2858V1_4939) | 97308..98240 | + | 933 | WP_000991832.1 | S-4TM family putative pore-forming effector | - |
| LQ127_RS25495 (AI2858V1_4941) | 99288..102404 | - | 3117 | WP_031311986.1 | HsdR family type I site-specific deoxyribonuclease | - |
| LQ127_RS25500 (AI2858V1_4942) | 102526..103797 | - | 1272 | WP_023142242.1 | restriction endonuclease subunit S | - |
| LQ127_RS25505 (AI2858V1_4943) | 103794..105302 | - | 1509 | WP_230139137.1 | type I restriction-modification system subunit M | - |
| LQ127_RS25510 (AI2858V1_4944) | 105533..105754 | + | 222 | WP_001190712.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| LQ127_RS25515 (AI2858V1_4945) | 105754..106134 | + | 381 | WP_001216034.1 | type II toxin-antitoxin system death-on-curing family toxin | - |
| LQ127_RS25520 (AI2858V1_4946) | 106139..106318 | + | 180 | WP_001513661.1 | hypothetical protein | - |
| LQ127_RS25525 (AI2858V1_4947) | 106346..106624 | + | 279 | Protein_122 | pdcB | - |
| LQ127_RS25530 (AI2858V1_REPA000000277) | 106629..107042 | + | 414 | Protein_123 | IS3 family transposase ISLad1 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|