MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 174054 bp
Accession: NZ_LR890752 Location: 1..174054 Organism: Klebsiella pneumoniae isolate KSB1_8C-sc-2280241 Replicon: plasmid 2
Accession: NZ_LR890752 Location: 1..174054 Organism: Klebsiella pneumoniae isolate KSB1_8C-sc-2280241 Replicon: plasmid 2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JMW25_RS25635 () | 1..1011 | + | 1011 | WP_017900946.1 | RepB family plasmid replication initiator protein | - |
| JMW25_RS25640 () | 1833..2573 | - | 741 | Protein_1 | site-specific integrase | - |
| JMW25_RS25645 () | 2918..3194 | + | 277 | Protein_2 | IS3 family transposase | - |
| JMW25_RS25650 () | 3332..3868 | - | 537 | WP_023288364.1 | hypothetical protein | - |
| JMW25_RS25655 () | 4079..5052 | - | 974 | Protein_4 | IS3 family transposase ISYps8 | Transposase |
| JMW25_RS25660 () | 5119..6134 | + | 1016 | Protein_5 | IS110 family transposase ISSaen1 | Transposase |
| JMW25_RS25665 () | 6360..6473 | - | 114 | Protein_6 | IS3 family transposase ISEhe4 | Transposase |
| JMW25_RS25670 () | 6826..7770 | - | 945 | WP_032413397.1 | ectoine utilization protein EutC | - |
| JMW25_RS25675 () | 7767..8786 | - | 1020 | WP_032731846.1 | pyridoxal-phosphate dependent enzyme | - |
| JMW25_RS25680 () | 8881..9606 | - | 726 | WP_148662571.1 | Glutamine transport ATP-binding protein GlnQ | VF |
| JMW25_RS25685 () | 9711..10493 | - | 783 | WP_032413390.1 | Glutamine transport ATP-binding protein GlnQ | VF |
| JMW25_RS25690 () | 10508..11164 | - | 657 | WP_048281129.1 | ectoine/hydroxyectoine ABC transporter permease subunit EhuD | - |
| JMW25_RS25695 () | 11161..11820 | - | 660 | WP_032413447.1 | ectoine/hydroxyectoine ABC transporter permease subunit EhuC | - |
| JMW25_RS25700 () | 11945..12799 | - | 855 | WP_032413386.1 | ectoine/hydroxyectoine ABC transporter substrate-binding protein EhuB | - |
| JMW25_RS25705 () | 12991..14400 | + | 1410 | WP_032413385.1 | PLP-dependent aminotransferase family protein | - |
| JMW25_RS25710 () | 14894..16084 | + | 1191 | WP_032413383.1 | ectoine hydrolase DoeA | - |
| JMW25_RS25715 () | 16097..17095 | + | 999 | WP_032413381.1 | N(2)-acetyl-L-2,4-diaminobutanoate deacetylase DoeB | - |
| JMW25_RS25720 () | 17142..18320 | + | 1179 | WP_032413379.1 | cystathionine gamma-synthase family protein | - |
| JMW25_RS25725 () | 18457..18804 | + | 348 | WP_032413377.1 | hypothetical protein | - |
| JMW25_RS25730 () | 18862..18987 | + | 126 | Protein_19 | IS256 family transposase ISAba42 | Transposase |
| JMW25_RS25735 () | 19121..19345 | - | 225 | Protein_20 | IS5 family transposase ISPan1 | Transposase |
| JMW25_RS25740 () | 19365..19550 | + | 186 | WP_071571073.1 | DUF2188 domain-containing protein | - |
| JMW25_RS25745 () | 19651..20163 | + | 513 | Protein_22 | DUF4113 domain-containing protein | - |
| JMW25_RS25750 () | 20263..20706 | + | 444 | WP_032413443.1 | DUF2384 domain-containing protein | Antitoxin Detail |
| JMW25_RS25755 () | 20703..21173 | + | 471 | WP_032413375.1 | RES family NAD+ phosphorylase | Toxin Detail |
| JMW25_RS25760 () | 21283..21543 | - | 261 | WP_017901409.1 | hypothetical protein | - |
| JMW25_RS25765 () | 22115..22492 | - | 378 | Protein_26 | transposase | - |
| JMW25_RS25770 () | 22626..23594 | + | 969 | WP_162887377.1 | IS5 family transposase IS903B | Transposase |
| JMW25_RS25775 () | 23829..25562 | - | 1734 | WP_004118832.1 | Glutathione import ATP-binding protein GsiA | VF |
| JMW25_RS25780 () | 25570..26517 | - | 948 | WP_049013026.1 | acetamidase/formamidase family protein | - |
| JMW25_RS25785 () | 26562..28166 | - | 1605 | WP_004152278.1 | ABC transporter substrate-binding protein | - |
| JMW25_RS25790 () | 28179..29099 | - | 921 | WP_004118227.1 | ABC transporter permease | - |
| JMW25_RS25795 () | 29099..29947 | - | 849 | WP_004118228.1 | ABC transporter permease | - |
| JMW25_RS25800 () | 29944..30537 | - | 594 | WP_049013025.1 | ANTAR domain-containing protein | - |
| JMW25_RS25805 () | 30534..31661 | - | 1128 | WP_004118840.1 | transporter substrate-binding protein | - |
| JMW25_RS25810 () | 32056..33024 | - | 969 | WP_074418888.1 | IS5 family transposase IS903B | Transposase |
| JMW25_RS25815 () | 33042..33179 | - | 138 | WP_064171890.1 | hypothetical protein | - |
| JMW25_RS25820 () | 33683..34541 | + | 859 | Protein_37 | IS3 family transposase ISEc52 | Transposase |
| JMW25_RS25825 () | 34823..35899 | + | 1077 | WP_000227969.1 | IS110 family transposase ISEc21 | Transposase |
| JMW25_RS25830 () | 35916..36050 | + | 135 | Protein_39 | transposase family protein | - |
| JMW25_RS25835 () | 36086..37054 | + | 969 | WP_181710278.1 | IS5 family transposase IS903B | Transposase |
| JMW25_RS25840 () | 37111..37278 | + | 168 | Protein_41 | IS3 family transposase | - |
| JMW25_RS25845 () | 37749..37868 | - | 120 | Protein_42 | IS3 family transposase | - |
| JMW25_RS25850 () | 38007..39983 | + | 1977 | WP_064171859.1 | TIR domain-containing protein | - |
| JMW25_RS25855 () | 42502..42987 | + | 486 | WP_032238615.1 | hypothetical protein | - |
| JMW25_RS25860 () | 42984..43433 | + | 450 | WP_010431201.1 | response regulator | - |
| JMW25_RS25865 () | 43430..44602 | + | 1173 | WP_032238613.1 | response regulator | - |
| JMW25_RS25870 () | 44703..45185 | + | 483 | WP_074188320.1 | DUF4231 domain-containing protein | - |
| JMW25_RS25875 () | 45230..45361 | - | 132 | Protein_48 | IS3 family transposase IS1400 | Transposase |
| JMW25_RS25880 () | 45468..46178 | - | 711 | WP_116397526.1 | IS3 family transposase ISBcen15 | Transposase |
| JMW25_RS25885 () | 46524..48260 | + | 1737 | WP_064171884.1 | AAA family ATPase | - |
| JMW25_RS25890 () | 48250..49668 | + | 1419 | WP_001134628.1 | UvrD-helicase domain-containing protein | - |
| JMW25_RS25895 () | 49917..50885 | - | 969 | WP_124070599.1 | IS5 family transposase IS903B | Transposase |
| JMW25_RS25900 () | 50887..51882 | - | 996 | WP_177951847.1 | IS5 family transposase IS903 | Transposase |
| JMW25_RS25905 () | 52208..52558 | - | 351 | WP_003032889.1 | DUF305 domain-containing protein | - |
| JMW25_RS25910 () | 52702..53133 | - | 432 | WP_000790483.1 | silver-binding protein SilE | - |
| JMW25_RS25915 () | 53384..54859 | - | 1476 | WP_049014823.1 | copper/silver sensor histidine kinase SilS | - |
| JMW25_RS25920 () | 54852..55532 | - | 681 | WP_001572351.1 | Transcriptional regulatory protein CusR | VF |
| JMW25_RS25925 () | 55722..57107 | + | 1386 | WP_000475512.1 | Cation efflux system protein CusC | VF |
| JMW25_RS25930 () | 57136..57489 | + | 354 | WP_001246153.1 | cation efflux system protein CusF | - |
| JMW25_RS25935 () | 57603..58895 | + | 1293 | WP_001485328.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| JMW25_RS25940 () | 58906..62052 | + | 3147 | WP_048298744.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| JMW25_RS25945 () | 62139..62579 | + | 441 | WP_008322815.1 | hypothetical protein | - |
| JMW25_RS25950 () | 62706..65153 | + | 2448 | WP_004098955.1 | Ag(+)-translocating P-type ATPase SilP | - |
| JMW25_RS25955 () | 65194..65391 | + | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| JMW25_RS25960 () | 65425..66162 | - | 738 | WP_004118669.1 | Murein DD-endopeptidase MepM | VF |
| JMW25_RS25965 () | 66451..66900 | - | 450 | WP_001023257.1 | copper resistance protein | - |
| JMW25_RS25970 () | 67134..68951 | + | 1818 | WP_048298742.1 | multicopper oxidase PcoA | - |
| JMW25_RS25975 () | 68957..69847 | + | 891 | WP_130943622.1 | copper resistance outer membrane transporter PcoB | - |
| JMW25_RS25980 () | 69887..70267 | + | 381 | WP_040221028.1 | copper resistance system metallochaperone PcoC | - |
| JMW25_RS25985 () | 70272..71201 | + | 930 | WP_000998778.1 | copper resistance inner membrane protein PcoD | - |
| JMW25_RS25990 () | 71256..71936 | + | 681 | WP_009309896.1 | Transcriptional activator protein CopR | VF |
| JMW25_RS25995 () | 71933..73333 | + | 1401 | WP_004152084.1 | copper resistance membrane spanning protein PcoS | - |
| JMW25_RS26000 () | 73549..73983 | + | 435 | WP_048298741.1 | hypothetical protein | - |
| JMW25_RS26005 () | 74395..74460 | - | 66 | WP_171005074.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| JMW25_RS26010 () | 74608..75611 | + | 1004 | Protein_75 | IS3 family transposase ISEcl1 | Transposase |
| JMW25_RS26015 () | 75631..76455 | + | 825 | Protein_76 | IS5 family transposase IS903 | Transposase |
| JMW25_RS26020 () | 76457..76843 | + | 387 | WP_048298739.1 | IS5/IS1182 family transposase | - |
| JMW25_RS26025 () | 77155..77391 | + | 237 | Protein_78 | IS66 family transposase IS682 | Transposase |
| JMW25_RS26030 () | 77447..77590 | - | 144 | Protein_79 | transposase | - |
| JMW25_RS26035 () | 77647..78344 | + | 698 | Protein_80 | IS1 family transposase IS1G | Transposase |
| JMW25_RS26040 () | 78368..79171 | - | 804 | WP_048298737.1 | hypothetical protein | - |
| JMW25_RS26045 () | 79295..80578 | - | 1284 | WP_110222738.1 | ISNCY family transposase ISLad2 | Transposase |
| JMW25_RS26050 () | 80818..81177 | + | 360 | Protein_83 | LysR family transcriptional regulator | - |
| JMW25_RS26055 () | 81339..82775 | - | 1437 | WP_048298736.1 | PLP-dependent aminotransferase family protein | - |
| JMW25_RS26060 () | 82874..83662 | + | 789 | WP_023288270.1 | arylamine N-acetyltransferase | - |
| JMW25_RS26065 () | 84004..84589 | + | 586 | Protein_86 | IS110 family transposase IS1618 | Transposase |
| JMW25_RS26070 () | 84989..85222 | + | 234 | Protein_87 | Tn3 family transposase TnpA_Tn3 | Transposase |
| JMW25_RS26075 () | 85400..86932 | + | 1533 | Protein_88 | IS3 family transposase ISKpn38 | Transposase |
| JMW25_RS26080 () | 87279..87976 | + | 698 | Protein_89 | IS1 family transposase IS1G | Transposase |
| JMW25_RS26085 () | 88045..89910 | - | 1866 | WP_048298735.1 | DUF262 domain-containing protein | - |
| JMW25_RS26090 () | 90943..91407 | + | 465 | WP_064171841.1 | hypothetical protein | - |
| JMW25_RS26095 () | 91407..92195 | + | 789 | WP_048298734.1 | hypothetical protein | - |
| JMW25_RS26100 () | 92209..92385 | + | 177 | WP_162887376.1 | hypothetical protein | - |
| JMW25_RS26105 () | 92457..93488 | - | 1032 | WP_072072824.1 | IS630 family transposase ISEc33 | Transposase |
| JMW25_RS26110 () | 93607..94817 | + | 1211 | WP_093515578.1 | IS3 family transposase ISEc36 | Transposase |
| JMW25_RS26115 () | 94829..95235 | + | 407 | Protein_96 | WYL domain-containing protein | - |
| JMW25_RS26120 () | 95274..96371 | + | 1098 | WP_048298731.1 | hypothetical protein | - |
| JMW25_RS26125 () | 96418..97989 | + | 1572 | WP_048298730.1 | ATP--cob(I)alamin adenosyltransferase | - |
| JMW25_RS26130 () | 97986..98258 | + | 273 | WP_071993384.1 | YkgJ family cysteine cluster protein | - |
| JMW25_RS26135 () | 98490..98795 | + | 306 | Protein_100 | IS481 family transposase ISEc18 | Transposase |
| JMW25_RS26140 () | 98869..99647 | + | 779 | Protein_101 | IS3 family transposase ISEc52 | Transposase |
| JMW25_RS26145 () | 99727..100862 | + | 1136 | WP_114139113.1 | IS3 family transposase IS1400 | Transposase |
| JMW25_RS26150 () | 100859..101556 | - | 698 | Protein_103 | IS1 family transposase | - |
| JMW25_RS26155 () | 102615..102731 | + | 117 | Protein_104 | transposase | - |
| JMW25_RS26160 () | 103151..103264 | + | 114 | WP_077253754.1 | IS3 family transposase | - |
| JMW25_RS26165 () | 103356..103496 | - | 141 | Protein_106 | diguanylate cyclase | - |
| JMW25_RS26170 () | 103519..104487 | + | 969 | WP_077263733.1 | IS5 family transposase IS903B | Transposase |
| JMW25_RS26175 () | 104533..105993 | - | 1461 | WP_201515207.1 | sensor domain-containing diguanylate cyclase | - |
| JMW25_RS26180 () | 106391..106813 | - | 423 | Protein_109 | IS3 family transposase ISEcl1 | Transposase |
| JMW25_RS26185 () | 106858..107826 | + | 969 | WP_077263862.1 | IS5 family transposase IS903B | Transposase |
| JMW25_RS26190 () | 108000..108221 | - | 222 | WP_032416992.1 | hypothetical protein | - |
| JMW25_RS26195 () | 109530..110227 | - | 698 | Protein_112 | IS1 family transposase IS1G | Transposase |
| JMW25_RS26200 () | 110488..111456 | - | 969 | WP_201515199.1 | IS5 family transposase IS903B | Transposase |
| JMW25_RS26205 () | 111718..113241 | - | 1524 | WP_117282697.1 | putative cyclic di-GMP phosphodiesterase PdeG | VF |
| JMW25_RS26215 () | 114998..115414 | - | 417 | WP_048298725.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| JMW25_RS26220 () | 115411..115641 | - | 231 | WP_001261276.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| JMW25_RS26225 () | 115894..118470 | - | 2577 | WP_053067542.1 | EstP | - |
| JMW25_RS26230 () | 118473..120680 | - | 2208 | WP_048298723.1 | AAA family ATPase | - |
| JMW25_RS26235 () | 121117..121344 | - | 228 | Protein_120 | hypothetical protein | - |
| JMW25_RS26240 () | 121411..122193 | - | 783 | WP_048298722.1 | IS21 family transposase ISSen3 | Transposase |
| JMW25_RS26245 () | 122190..123212 | - | 1023 | WP_048298721.1 | IS21 family transposase ISSen3 | Transposase |
| JMW25_RS26250 () | 123300..123625 | + | 326 | Protein_123 | IS5 family transposase IS903B | Transposase |
| JMW25_RS26255 () | 124049..125017 | + | 969 | WP_080901900.1 | IS5 family transposase IS903 | Transposase |
| JMW25_RS26260 () | 125287..125466 | - | 180 | WP_007372130.1 | hypothetical protein | - |
| JMW25_RS26265 () | 125545..126242 | + | 698 | Protein_126 | IS1 family transposase IS1X4 | Transposase |
| JMW25_RS26270 () | 126702..126914 | + | 213 | Protein_127 | IS3 family transposase ISYps8 | Transposase |
| JMW25_RS26275 () | 126959..127927 | - | 969 | WP_201515201.1 | IS5 family transposase IS903B | Transposase |
| JMW25_RS26280 () | 127981..128676 | - | 696 | Protein_129 | IS1 family transposase | - |
| JMW25_RS26285 () | 128732..129436 | - | 705 | Protein_130 | IS3 family transposase ISKpn38 | Transposase |
| JMW25_RS26290 () | 129480..129788 | - | 309 | Protein_131 | IS3 family transposase ISLad1 | Transposase |
| JMW25_RS26295 () | 129805..130881 | - | 1077 | WP_000227969.1 | IS110 family transposase ISEc21 | Transposase |
| JMW25_RS26300 () | 131163..132022 | - | 860 | Protein_133 | IS3 family transposase ISEc52 | Transposase |
| JMW25_RS26305 () | 132452..133354 | - | 903 | WP_004181695.1 | HTH-type transcriptional regulator DmlR | VF |
| JMW25_RS26310 () | 133647..134366 | + | 720 | WP_040217073.1 | SDR family oxidoreductase | - |
| JMW25_RS26315 () | 134433..135755 | - | 1323 | WP_040217071.1 | 2-aminohexano-6-lactam racemase | VF |
| JMW25_RS26320 () | 135752..137218 | - | 1467 | WP_049165011.1 | APC family permease | - |
| JMW25_RS26325 () | 137287..138657 | - | 1371 | WP_043875145.1 | glutamine synthetase family protein | - |
| JMW25_RS26330 () | 138829..139680 | + | 852 | WP_043875152.1 | MurR/RpiR family transcriptional regulator | - |
| JMW25_RS26335 () | 139735..140484 | + | 750 | WP_043875144.1 | N-formylglutamate amidohydrolase | - |
| JMW25_RS26340 () | 140488..141135 | + | 648 | WP_023328945.1 | cysteine hydrolase | - |
| JMW25_RS26345 () | 141177..142145 | + | 969 | WP_077263866.1 | IS5 family transposase IS903 | Transposase |
| JMW25_RS26350 () | 142318..142623 | + | 306 | WP_023328947.1 | hypothetical protein | VF |
| JMW25_RS26355 () | 143741..144055 | + | 315 | WP_023288299.1 | hypothetical protein | - |
| JMW25_RS26360 () | 144162..144451 | - | 290 | Protein_145 | Tn3 family transposase | - |
| JMW25_RS26365 () | 144502..145254 | - | 753 | WP_004729622.1 | alpha/beta hydrolase | - |
| JMW25_RS26370 () | 145495..146364 | + | 870 | WP_001567390.1 | DMT family transporter | - |
| JMW25_RS26375 () | 146498..147721 | + | 1224 | WP_023287190.1 | aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme | - |
| JMW25_RS26380 () | 147907..148680 | - | 774 | WP_004729618.1 | SDR family oxidoreductase | - |
| JMW25_RS26385 () | 148746..149447 | - | 702 | WP_001194072.1 | DsbA family oxidoreductase | - |
| JMW25_RS26390 () | 149513..150619 | - | 1107 | WP_023287189.1 | alkene reductase | - |
| JMW25_RS26395 () | 150833..151162 | + | 330 | WP_002431133.1 | thioredoxin family protein | - |
| JMW25_RS26400 () | 151192..151530 | - | 339 | WP_000888080.1 | carboxymuconolactone decarboxylase family protein | - |
| JMW25_RS26405 () | 151535..152116 | - | 582 | WP_000210409.1 | HTH-type transcriptional repressor NemR | VF |
| JMW25_RS26410 () | 152258..152815 | - | 558 | WP_000108589.1 | OsmC family protein | - |
| JMW25_RS26415 () | 153000..153209 | - | 210 | Protein_156 | Tn3 family transposase TnpR_ISSba14 | Transposase |
| JMW25_RS26420 () | 153282..153691 | + | 410 | Protein_157 | Tn3 family transposase | - |
| JMW25_RS26425 () | 153921..154403 | - | 483 | WP_004210306.1 | hypothetical protein | - |
| JMW25_RS26430 () | 156528..157184 | - | 657 | WP_023287188.1 | hypothetical protein | - |
| JMW25_RS26435 () | 158019..158918 | - | 900 | WP_004026560.1 | RepB family plasmid replication initiator protein | - |
| JMW25_RS26440 () | 159239..160300 | - | 1062 | WP_048298749.1 | hypothetical protein | - |
| JMW25_RS26445 () | 160386..160640 | - | 255 | WP_016946352.1 | transcriptional regulator | - |
| JMW25_RS26450 () | 160817..161953 | + | 1137 | WP_014386529.1 | tyrosine-type recombinase/integrase | - |
| JMW25_RS26455 () | 162019..162336 | - | 318 | WP_004026552.1 | hypothetical protein | - |
| JMW25_RS26460 () | 162487..162810 | - | 324 | WP_048298750.1 | hypothetical protein | - |
| JMW25_RS26465 () | 162807..163565 | - | 759 | WP_048298751.1 | hypothetical protein | - |
| JMW25_RS26470 () | 163562..164521 | - | 960 | WP_048298752.1 | DNA replication protein | - |
| JMW25_RS26475 () | 164564..164971 | - | 408 | WP_004186937.1 | hypothetical protein | - |
| JMW25_RS26480 () | 164981..165424 | - | 444 | WP_020477096.1 | hypothetical protein | - |
| JMW25_RS26490 () | 166720..168312 | - | 1593 | WP_048298753.1 | IS66 family transposase ISKox1 | Transposase |
| JMW25_RS26495 () | 168343..168693 | - | 351 | WP_048298754.1 | IS66 family transposase ISKox1 | Transposase |
| JMW25_RS26500 () | 168690..169130 | - | 441 | WP_048298755.1 | IS66 family transposase ISKox1 | Transposase |
| JMW25_RS26505 () | 169215..169508 | + | 294 | Protein_174 | DUF4113 domain-containing protein | - |
| JMW25_RS26510 () | 169587..169815 | + | 229 | Protein_175 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| JMW25_RS26515 () | 171188..172159 | - | 972 | WP_004117790.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| JMW25_RS26520 () | 172159..173325 | - | 1167 | WP_023287153.1 | hypothetical protein | VF |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|