MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 138469 bp
Accession: NZ_LR890324 Location: 1..138469 Organism: Klebsiella pneumoniae isolate INF348-sc-2280170 Replicon: plasmid 2
Accession: NZ_LR890324 Location: 1..138469 Organism: Klebsiella pneumoniae isolate INF348-sc-2280170 Replicon: plasmid 2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JMW45_RS25210 () | 1..1011 | + | 1011 | WP_000200070.1 | RepB family plasmid replication initiator protein | - |
| JMW45_RS25215 () | 1708..2448 | - | 741 | WP_004187098.1 | IS91 family transposase ISMno23 | Transposase |
| JMW45_RS25220 () | 2795..3915 | + | 1121 | WP_094645293.1 | IS3 family transposase ISKpn34 | Transposase |
| JMW45_RS25225 () | 4304..4612 | - | 309 | Protein_3 | IS3 family transposase ISLad1 | Transposase |
| JMW45_RS25230 () | 4628..5710 | - | 1083 | WP_031592182.1 | IS110 family transposase ISEc21 | Transposase |
| JMW45_RS25235 () | 5990..6526 | - | 537 | Protein_5 | IS3 family transposase ISEhe3 | Transposase |
| JMW45_RS25240 () | 6549..6923 | + | 375 | Protein_6 | IS21 family transposase ISEc62 | Transposase |
| JMW45_RS25245 () | 7272..8240 | + | 969 | WP_074194210.1 | IS5 family transposase IS903B | Transposase |
| JMW45_RS25250 () | 8356..9609 | - | 1254 | WP_003846917.1 | lactose permease | - |
| JMW45_RS25255 () | 9661..12735 | - | 3075 | WP_004187094.1 | beta-galactosidase | - |
| JMW45_RS25260 () | 12857..13939 | - | 1083 | WP_004206569.1 | DNA-binding transcriptional repressor LacI | - |
| JMW45_RS25265 () | 14321..15313 | + | 993 | WP_032414406.1 | zinc-binding alcohol dehydrogenase family protein | - |
| JMW45_RS25270 () | 15673..16125 | - | 453 | Protein_12 | Tn3 family transposase TnpA_ISSba14 | Transposase |
| JMW45_RS25275 () | 16321..17489 | + | 1169 | WP_085929673.1 | IS3 family transposase ISLad1 | Transposase |
| JMW45_RS25280 () | 17499..18146 | + | 648 | Protein_14 | IS6 family transposase IS26 | Transposase |
| JMW45_RS25285 () | 18201..18932 | + | 732 | Protein_15 | DNA helicase UvrD | - |
| JMW45_RS25290 () | 19470..20384 | + | 915 | WP_031592169.1 | HNH endonuclease | - |
| JMW45_RS25295 () | 20570..20920 | - | 351 | WP_004187110.1 | DUF305 domain-containing protein | - |
| JMW45_RS25300 () | 21068..21499 | - | 432 | WP_004187113.1 | silver-binding protein SilE | - |
| JMW45_RS25305 () | 21750..23225 | - | 1476 | WP_000555737.1 | copper/silver sensor histidine kinase SilS | - |
| JMW45_RS25310 () | 23218..23898 | - | 681 | WP_000697969.1 | Transcriptional regulatory protein CusR | VF |
| JMW45_RS25315 () | 24088..25473 | + | 1386 | WP_000475503.1 | Cation efflux system protein CusC | VF |
| JMW45_RS25320 () | 25502..25855 | + | 354 | WP_001246153.1 | cation efflux system protein CusF | - |
| JMW45_RS25325 () | 25969..27261 | + | 1293 | WP_004098959.1 | Cu(+)/Ag(+) efflux RND transporter periplasmic adaptor subunit SilB | - |
| JMW45_RS25330 () | 27272..30418 | + | 3147 | WP_004098958.1 | Cu(+)/Ag(+) efflux RND transporter permease subunit SilA | - |
| JMW45_RS25335 () | 30505..30945 | + | 441 | WP_000758228.1 | hypothetical protein | - |
| JMW45_RS25340 () | 31072..33519 | + | 2448 | WP_201522425.1 | heavy metal translocating P-type ATPase | - |
| JMW45_RS25345 () | 33560..33757 | + | 198 | WP_000843497.1 | DUF2933 domain-containing protein | - |
| JMW45_RS25350 () | 33791..34528 | - | 738 | WP_000287501.1 | Murein DD-endopeptidase MepM | VF |
| JMW45_RS25355 () | 34817..35266 | - | 450 | WP_031591799.1 | copper resistance protein | - |
| JMW45_RS25360 () | 35500..37317 | + | 1818 | WP_000925242.1 | multicopper oxidase PcoA | - |
| JMW45_RS25365 () | 37323..38213 | + | 891 | WP_020803534.1 | copper resistance outer membrane transporter PcoB | - |
| JMW45_RS25370 () | 38253..38633 | + | 381 | WP_000025662.1 | copper resistance system metallochaperone PcoC | - |
| JMW45_RS25375 () | 38638..39567 | + | 930 | WP_201522426.1 | copper homeostasis membrane protein CopD | - |
| JMW45_RS25380 () | 39622..40302 | + | 681 | WP_001188930.1 | Transcriptional activator protein CopR | VF |
| JMW45_RS25385 () | 40299..41699 | + | 1401 | WP_002436614.1 | copper resistance membrane spanning protein PcoS | - |
| JMW45_RS25390 () | 41915..42349 | + | 435 | WP_004118347.1 | hypothetical protein | - |
| JMW45_RS25395 () | 42736..43716 | + | 981 | WP_008503529.1 | IS5 family transposase ISKpn26 | Transposase |
| JMW45_RS25400 () | 44009..45598 | - | 1590 | WP_015632444.1 | IS66 family transposase ISEcl6 | Transposase |
| JMW45_RS25405 () | 45628..45978 | - | 351 | WP_032414478.1 | IS66 family transposase IS682 | Transposase |
| JMW45_RS25410 () | 45975..46382 | - | 408 | WP_015632445.1 | IS66 family transposase ISCro1 | Transposase |
| JMW45_RS25415 () | 46462..46845 | + | 384 | Protein_41 | IS66 family transposase ISKox1 | Transposase |
| JMW45_RS25420 () | 46842..47192 | + | 351 | WP_004189161.1 | IS66 family transposase ISKox1 | Transposase |
| JMW45_RS25425 () | 47223..48815 | + | 1593 | WP_014839879.1 | IS66 family transposase ISKox1 | Transposase |
| JMW45_RS25430 () | 48881..49861 | - | 981 | Protein_44 | IS5 family transposase | - |
| JMW45_RS25435 () | 49919..50458 | + | 540 | Protein_45 | DMT family transporter | - |
| JMW45_RS25440 () | 50526..50654 | - | 129 | Protein_46 | transcriptional regulator | - |
| JMW45_RS25445 () | 50714..51327 | - | 614 | Protein_47 | hypothetical protein | - |
| JMW45_RS25450 () | 51678..51911 | - | 234 | Protein_48 | arsenate reductase | - |
| JMW45_RS25455 () | 51984..53152 | + | 1169 | WP_085929673.1 | IS3 family transposase ISLad1 | Transposase |
| JMW45_RS25460 () | 53161..53355 | - | 195 | Protein_50 | arsenate reductase | - |
| JMW45_RS25465 () | 53368..54657 | - | 1290 | WP_004118136.1 | arsenite efflux transporter membrane subunit ArsB | - |
| JMW45_RS25470 () | 54705..56456 | - | 1752 | WP_060579424.1 | arsenite efflux transporter ATPase subunit ArsA | - |
| JMW45_RS25475 () | 56474..56836 | - | 363 | WP_004118102.1 | arsenite efflux transporter metallochaperone ArsD | - |
| JMW45_RS25480 () | 56884..57237 | - | 354 | WP_001114073.1 | As(III)-sensing metalloregulatory transcriptional repressor ArsR | - |
| JMW45_RS25485 () | 58026..58403 | + | 378 | Protein_55 | LysR family transcriptional regulator | - |
| JMW45_RS25490 () | 58784..59752 | + | 969 | WP_080465744.1 | IS5 family transposase IS903B | Transposase |
| JMW45_RS25495 () | 59909..61906 | + | 1998 | WP_023307506.1 | choline BCCT transporter BetT | - |
| JMW45_RS25500 () | 62057..62754 | + | 698 | Protein_58 | IS1 family transposase IS1X2 | Transposase |
| JMW45_RS25505 () | 62764..64029 | + | 1266 | Protein_59 | DUF2254 domain-containing protein | - |
| JMW45_RS25510 () | 65061..65997 | - | 937 | Protein_60 | ISNCY family transposase | - |
| JMW45_RS25515 () | 66107..66277 | + | 171 | Protein_61 | IS3 family transposase ISKpn38 | Transposase |
| JMW45_RS25520 () | 66275..66382 | + | 108 | Protein_62 | IS3 family transposase ISKpn38 | Transposase |
| JMW45_RS25525 () | 66616..67320 | - | 705 | WP_031591821.1 | toll/interleukin-1 receptor domain-containing protein | - |
| JMW45_RS25530 () | 67480..68826 | - | 1347 | WP_077251107.1 | ISNCY family transposase ISLad2 | Transposase |
| JMW45_RS25535 () | 69037..69519 | - | 483 | WP_004187044.1 | GNAT family N-acetyltransferase | Toxin Detail |
| JMW45_RS25540 () | 69507..69773 | - | 267 | WP_003026799.1 | DUF1778 domain-containing protein | Antitoxin Detail |
| JMW45_RS25545 () | 69924..70628 | + | 705 | WP_060579418.1 | IS6 family transposase IS26 | Transposase |
| JMW45_RS25550 () | 70787..73372 | - | 2586 | WP_004187040.1 | hypothetical protein | VF |
| JMW45_RS25555 () | 73341..73586 | - | 246 | WP_032238678.1 | hypothetical protein | - |
| JMW45_RS25560 () | 73644..74624 | - | 981 | Protein_70 | IS5 family transposase ISKpn26 | Transposase |
| JMW45_RS25565 () | 74693..74860 | - | 168 | Protein_71 | transposase | - |
| JMW45_RS25570 () | 75001..75963 | - | 963 | WP_004152113.1 | M48 family metalloprotease | - |
| JMW45_RS25575 () | 75950..76699 | - | 750 | WP_004187033.1 | phosphate-starvation-inducible PsiE family protein | - |
| JMW45_RS25580 () | 76937..77134 | - | 198 | Protein_74 | hypothetical protein | - |
| JMW45_RS25585 () | 77134..79929 | - | 2796 | WP_004152116.1 | ATP-dependent Clp protease ATP-binding subunit ClpC | VF |
| JMW45_RS25590 () | 80035..80604 | - | 570 | WP_004152117.1 | hypothetical protein | VF |
| JMW45_RS25595 () | 80639..80920 | - | 282 | WP_013307885.1 | helix-turn-helix domain-containing protein | - |
| JMW45_RS25600 () | 81164..81427 | - | 264 | WP_004118208.1 | hypothetical protein | - |
| JMW45_RS25605 () | 81442..81705 | + | 264 | WP_004187027.1 | transposase | - |
| JMW45_RS25610 () | 81650..81766 | + | 117 | Protein_80 | transposase domain-containing protein | - |
| JMW45_RS25615 () | 81954..82378 | + | 425 | Protein_81 | IS1 family transposase IS1G | Transposase |
| JMW45_RS25620 () | 82668..82916 | + | 249 | WP_004187025.1 | plasmid stabilization protein | Antitoxin Detail |
| JMW45_RS25625 () | 82906..83190 | + | 285 | WP_004187019.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| JMW45_RS25630 () | 83206..84561 | - | 1356 | WP_004187017.1 | ISNCY family transposase ISCARN112 | Transposase |
| JMW45_RS25635 () | 84643..84942 | - | 300 | Protein_85 | conjugal transfer protein TraH | - |
| JMW45_RS25640 () | 84940..85423 | - | 484 | Protein_86 | hypothetical protein | - |
| JMW45_RS25645 () | 85440..85964 | - | 525 | Protein_87 | hypothetical protein | - |
| JMW45_RS25650 () | 87507..87971 | + | 465 | WP_004187010.1 | hypothetical protein | - |
| JMW45_RS25655 () | 87971..88591 | + | 621 | Protein_89 | hypothetical protein | - |
| JMW45_RS25660 () | 88537..89117 | + | 581 | Protein_90 | IS1 family transposase IS1X4 | Transposase |
| JMW45_RS25665 () | 89430..91175 | - | 1746 | WP_004187005.1 | ATP-grasp domain-containing protein | - |
| JMW45_RS25670 () | 91175..92758 | - | 1584 | WP_004181711.1 | urea amidolyase family protein | - |
| JMW45_RS25675 () | 92771..93577 | - | 807 | WP_004187003.1 | putative hydro-lyase | - |
| JMW45_RS25680 () | 93574..94347 | - | 774 | WP_004181708.1 | LamB/YcsF family protein | - |
| JMW45_RS25685 () | 94356..95600 | - | 1245 | WP_004181707.1 | divalent metal cation transporter | - |
| JMW45_RS25690 () | 95940..96590 | + | 651 | WP_004181705.1 | GntR family transcriptional regulator | - |
| JMW45_RS25695 () | 96623..97320 | - | 698 | Protein_97 | IS1 family transposase IS1X4 | Transposase |
| JMW45_RS25700 () | 97370..98824 | + | 1455 | WP_100206809.1 | ATP-grasp domain-containing protein | - |
| JMW45_RS25705 () | 98865..99701 | - | 837 | WP_004186999.1 | DUF1989 domain-containing protein | - |
| JMW45_RS25710 () | 99701..100423 | - | 723 | WP_004186998.1 | GntR family transcriptional regulator | - |
| JMW45_RS25715 () | 100433..101941 | - | 1509 | WP_004186997.1 | Vitamin B12 import ATP-binding protein BtuD | VF |
| JMW45_RS25720 () | 101966..102781 | - | 816 | WP_004186996.1 | ABC transporter substrate-binding protein | - |
| JMW45_RS25725 () | 104119..105286 | + | 1168 | WP_096810283.1 | IS3 family transposase ISLad1 | Transposase |
| JMW45_RS25730 () | 105362..105664 | - | 303 | Protein_104 | IS3 family transposase ISKpn38 | Transposase |
| JMW45_RS25735 () | 105774..106643 | + | 870 | Protein_105 | ISNCY family transposase ISKpn21 | Transposase |
| JMW45_RS25740 () | 106677..109661 | - | 2985 | WP_032742905.1 | Tn3 family transposase TnpA_ISSba14 | Transposase |
| JMW45_RS25745 () | 109821..110405 | + | 585 | WP_008502231.1 | Tn3 family transposase TnpR_ISYps3 | Transposase |
| JMW45_RS25750 () | 110590..111147 | + | 558 | WP_000108589.1 | OsmC family protein | - |
| JMW45_RS25755 () | 111289..111870 | + | 582 | WP_023304048.1 | HTH-type transcriptional repressor NemR | VF |
| JMW45_RS25760 () | 111875..112213 | + | 339 | WP_000888080.1 | carboxymuconolactone decarboxylase family protein | - |
| JMW45_RS25765 () | 112243..112572 | - | 330 | WP_031591986.1 | thioredoxin family protein | - |
| JMW45_RS25770 () | 112785..113891 | + | 1107 | WP_060579419.1 | alkene reductase | - |
| JMW45_RS25775 () | 113957..114658 | + | 702 | WP_031591983.1 | DsbA family oxidoreductase | - |
| JMW45_RS25780 () | 114724..115497 | + | 774 | WP_004729618.1 | SDR family oxidoreductase | - |
| JMW45_RS25785 () | 116038..117018 | - | 981 | WP_201522423.1 | IS5 family transposase ISKpn26 | Transposase |
| JMW45_RS25790 () | 117209..117634 | - | 426 | WP_031591991.1 | glutaredoxin-dependent arsenate reductase | - |
| JMW45_RS25795 () | 117647..118936 | - | 1290 | WP_031591992.1 | arsenic transporter | - |
| JMW45_RS25800 () | 118983..120734 | - | 1752 | WP_031591994.1 | arsenical pump-driving ATPase | - |
| JMW45_RS25805 () | 120751..121113 | - | 363 | WP_031591995.1 | arsenite efflux transporter metallochaperone ArsD | - |
| JMW45_RS25810 () | 121161..121514 | - | 354 | WP_031591996.1 | As(III)-sensing metalloregulatory transcriptional repressor ArsR | - |
| JMW45_RS25815 () | 121777..121917 | + | 141 | Protein_121 | NAD(P)H-dependent oxidoreductase | - |
| JMW45_RS25820 () | 122590..123615 | + | 1026 | WP_031592191.1 | LacI family transcriptional regulator | - |
| JMW45_RS25825 () | 123919..124872 | + | 954 | WP_048286516.1 | ABC transporter substrate-binding protein | - |
| JMW45_RS25830 () | 124936..126468 | + | 1533 | WP_201522424.1 | Ribose import ATP-binding protein RbsA | VF |
| JMW45_RS25835 () | 126455..127474 | + | 1020 | WP_031591938.1 | ribose ABC transporter permease | - |
| JMW45_RS25840 () | 127552..128922 | + | 1371 | WP_031591936.1 | hypothetical protein | - |
| JMW45_RS25845 () | 128919..129839 | + | 921 | WP_031591935.1 | carbohydrate kinase | - |
| JMW45_RS25850 () | 130085..130225 | + | 141 | WP_162833785.1 | hypothetical protein | - |
| JMW45_RS25855 () | 130215..130523 | - | 309 | Protein_129 | putative fimbrial chaperone EcpE | VF |
| JMW45_RS25860 () | 130568..131388 | + | 821 | Protein_130 | IS5 family transposase ISPan1 | Transposase |
| JMW45_RS25865 () | 131417..132121 | - | 705 | Protein_131 | IS6 family transposase IS26 | Transposase |
| JMW45_RS25870 () | 132186..132383 | + | 198 | Protein_132 | peptidase | - |
| JMW45_RS25875 () | 132383..133654 | + | 1272 | WP_004187101.1 | Y-family DNA polymerase | - |
| JMW45_RS25880 () | 133733..133984 | + | 252 | WP_004187100.1 | hypothetical protein | - |
| JMW45_RS25885 () | 134038..134343 | + | 306 | WP_000534920.1 | hypothetical protein | - |
| JMW45_RS25890 () | 135592..136563 | - | 972 | WP_000817038.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| JMW45_RS25895 () | 136563..137729 | - | 1167 | WP_000523812.1 | hypothetical protein | VF |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|