MGE detailed information

MGE type: Conjugative plasmid        MGE length: 160467 bp
Accession: NZ_LR890300        Location: 1..160467         Organism: Escherichia coli isolate MSB1_3B-sc-2280406       Replicon: plasmid 2


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JM188_RS24525 () 1..978 + 978 WP_000361610.1 RepB family plasmid replication initiator protein -
JM188_RS24530 () 1263..2003 - 741 WP_001066941.1 tyrosine-type recombinase/integrase -
JM188_RS24535 () 2124..2312 - 189 WP_001309252.1 hypothetical protein -
JM188_RS24540 () 2679..3848 + 1170 WP_001072358.1 hypothetical protein -
JM188_RS24545 () 4074..4249 - 176 Protein_4 IS3 family transposase -
JM188_RS24550 () 4695..4967 - 273 WP_001322642.1 adhesin biosynthesis transcription regulatory family protein -
JM188_RS24555 () 5492..5928 - 437 Protein_6 IS3 family transposase IS2 Transposase
JM188_RS24560 () 6210..8180 + 1971 WP_001298664.1 Hemin receptor VF
JM188_RS24565 () 8187..8978 + 792 WP_000977394.1 DUF4198 domain-containing protein -
JM188_RS24570 () 9041..9649 - 609 Protein_9 IS66 family transposase ISEc22 Transposase
JM188_RS24575 () 9717..10499 - 783 WP_001300609.1 IS21 family transposase IS100kyp Transposase
JM188_RS24580 () 10496..11518 - 1023 WP_001310017.1 IS21 family transposase IS100kyp Transposase
JM188_RS24585 () 11604..12549 - 946 Protein_12 IS66 family transposase ISEc8 Transposase
JM188_RS24590 () 12598..12945 - 348 WP_000612626.1 IS66 family transposase ISKpn24 Transposase
JM188_RS24595 () 12942..13346 - 405 WP_000839179.1 IS66 family transposase ISEc22 Transposase
JM188_RS24600 () 13375..13758 - 384 Protein_15 IS3 family transposase IS629 Transposase
JM188_RS24605 () 13848..15356 - 1509 WP_001189113.1 group II intron reverse transcriptase/maturase -
JM188_RS24610 () 16029..16768 - 740 Protein_17 IS3 family transposase IS629 Transposase
JM188_RS24615 () 16794..17099 + 306 Protein_18 IS91 family transposase ISSbo1 Transposase
JM188_RS24620 () 17622..18797 - 1176 WP_001020413.1 putative protein YncE VF
JM188_RS24625 () 18866..21127 - 2262 WP_001100763.1 TonB-dependent receptor -
JM188_RS24630 () 21296..22072 - 777 WP_000981091.1 energy transducer TonB -
JM188_RS24635 () 22080..22955 - 876 WP_001224623.1 ChaN family lipoprotein -
JM188_RS24640 () 23287..23834 - 548 Protein_23 replication initiation protein -
JM188_RS24645 () 25406..25741 - 336 WP_001080732.1 colicin transporter -
JM188_RS24650 () 25870..26217 + 348 WP_000142452.1 hypothetical protein -
JM188_RS24655 () 26237..26746 - 510 WP_000194542.1 hypothetical protein -
JM188_RS24660 () 26743..27003 - 261 WP_000371882.1 hypothetical protein -
JM188_RS24665 () 27105..27844 + 740 Protein_28 IS3 family transposase IS629 Transposase
JM188_RS24670 () 28517..28831 + 315 Protein_29 IS5 family transposase ISKpn26 Transposase
JM188_RS24675 () 28832..29005 + 174 Protein_30 IS5 family transposase ISKpn26 Transposase
JM188_RS24680 () 29155..29788 - 634 Protein_31 histidine-type phosphatase -
JM188_RS24685 () 29910..30395 - 486 WP_000874189.1 hypothetical protein -
JM188_RS24690 () 30420..30905 - 486 WP_001267176.1 TlpA family protein disulfide reductase -
JM188_RS24695 () 30892..31587 - 696 WP_000117262.1 Lipoprotein-releasing system ATP-binding protein LolD VF
JM188_RS24700 () 31592..32722 - 1131 WP_000729220.1 ABC transporter permease -
JM188_RS24705 () 32712..33995 - 1284 WP_000964653.1 ABC transporter permease -
JM188_RS24710 () 33998..35377 - 1380 WP_000119836.1 DUF2318 domain-containing protein -
JM188_RS24715 () 35481..36008 - 528 WP_000178050.1 iron transporter -
JM188_RS24720 () 36049..37935 - 1887 WP_000118029.1 FTR1 family iron permease -
JM188_RS24725 () 38282..39097 - 816 WP_012372823.1 Na(+)-translocating NADH-quinone reductase subunit C -
JM188_RS24730 () 39280..39786 - 507 WP_000949452.1 protein disulfide oxidoreductase -
JM188_RS24735 () 39776..39934 - 159 WP_000449408.1 DsbA family protein -
JM188_RS24740 () 40084..40197 - 114 Protein_43 IS6 family transposase -
JM188_RS24745 () 40397..41094 + 698 Protein_44 IS1 family transposase IS1R Transposase
JM188_RS24750 () 41109..41327 + 219 Protein_45 IS4 family transposase -
JM188_RS24755 () 41377..42081 - 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
JM188_RS24760 () 42140..42889 - 750 Protein_47 IS91 family transposase ISAzo26 Transposase
JM188_RS24765 () 43047..43520 + 474 WP_001389366.1 trimethoprim-resistant dihydrofolate reductase DfrA17 -
JM188_RS24770 () 43651..44439 + 789 WP_000503573.1 Streptomycin 3''-adenylyltransferase ARG
JM188_RS24775 () 44645..44992 + 348 WP_000679427.1 Multidrug transporter EmrE ARG
JM188_RS24780 () 44986..45825 + 840 WP_000259031.1 Dihydropteroate synthase ARG
JM188_RS24785 () 45953..46156 + 204 WP_000376616.1 hypothetical protein -
JM188_RS24790 () 46312..47517 + 1206 WP_000184001.1 chromate efflux transporter -
JM188_RS24795 () 47528..47833 + 306 WP_000130000.1 Transcriptional regulator Relaxase
JM188_RS24800 () 47877..47942 + 66 Protein_55 EAL domain-containing protein -
JM188_RS24805 () 48060..48824 + 765 WP_001389365.1 IS6 family transposase IS6100 Transposase
JM188_RS24810 () 49317..49901 - 585 WP_001137892.1 TetR family transcriptional regulator -
JM188_RS24815 () 49901..51139 - 1239 WP_000004159.1 MFS transporter -
JM188_RS24820 () 51136..52041 - 906 WP_000219391.1 hypothetical protein ARG
JM188_RS24825 () 52163..52867 - 705 WP_001067855.1 IS6 family transposase IS26 Transposase
JM188_RS24830 () 52928..53104 + 177 Protein_61 replication protein C -
JM188_RS24835 () 53412..54227 + 816 WP_001043260.1 Dihydropteroate synthase ARG
JM188_RS24840 () 54288..55091 + 804 WP_001082319.1 Aminoglycoside 3'-phosphotransferase ARG
JM188_RS24845 () 55091..55927 + 837 WP_000480972.1 hypothetical protein ARG
JM188_RS24850 () 55981..56217 + 237 WP_042005022.1 hypothetical protein -
JM188_RS24855 () 56249..56875 - 627 WP_031606906.1 tetracycline resistance transcriptional repressor TetR(A) -
JM188_RS24860 () 56981..58180 + 1200 WP_000804064.1 Tetracycline resistance protein, class C ARG
JM188_RS24865 () 58212..58442 - 231 Protein_68 EamA family transporter -
JM188_RS24870 () 58497..59201 - 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
JM188_RS24875 () 59267..60182 - 916 Protein_70 IS1182 family transposase ISCfr1 Transposase
JM188_RS24880 () 60297..61433 - 1137 WP_000080860.1 DUF3883 domain-containing protein -
JM188_RS24885 () 61484..61711 - 228 WP_000248278.1 hypothetical protein -
JM188_RS24890 () 61735..61926 + 192 WP_000951934.1 hypothetical protein -
JM188_RS24895 () 62408..62854 - 447 Protein_74 tunicamycin resistance protein -
JM188_RS24900 () 62918..63622 + 705 WP_001067858.1 IS6 family transposase IS15DI Transposase
JM188_RS24905 () 63674..63823 + 150 Protein_76 type II toxin-antitoxin system antitoxin PemI -
JM188_RS24910 () 63756..64157 + 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
JM188_RS24915 () 64442..65752 + 1311 WP_001262765.1 DUF262 domain-containing protein -
JM188_RS24920 () 65781..65879 + 99 Protein_79 IS1 family transposase -
JM188_RS24925 () 66029..66889 - 861 WP_000027057.1 Beta-lactamase TEM ARG
JM188_RS24930 () 67072..67629 - 558 WP_001235713.1 Tn3 family transposase TnpR_Tn3 Transposase
JM188_RS24935 () 67793..68182 + 390 Protein_82 Tn3 family transposase TnpA_Tn3 Transposase
JM188_RS24940 () 68250..69347 - 1098 Protein_83 TonB-dependent receptor -
JM188_RS24945 () 69404..70372 - 969 WP_013362812.1 IS5 family transposase IS903B Transposase
JM188_RS24950 () 70407..71282 - 876 WP_032277257.1 Beta-lactamase CTX-M-97 ARG
JM188_RS24955 () 71532..71711 - 180 Protein_86 IS1380 family transposase -
JM188_RS24960 () 71776..72480 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
JM188_RS24965 () 72803..74335 - 1533 WP_013362816.1 IS91 family transposase ISVsa3 Transposase
JM188_RS24970 () 74562..74903 - 342 WP_023909256.1 60 kDa chaperonin VF
JM188_RS24975 () 74864..75313 - 450 WP_013362817.1 hypothetical protein -
JM188_RS24980 () 75828..75998 - 171 WP_170852050.1 rRNA adenine methyltransferase -
JM188_RS24985 () 75943..76680 - 738 WP_013362818.1 rRNA adenine N-6-methyltransferase ARG
JM188_RS24990 () 76806..76901 - 96 WP_013362819.1 23S rRNA methyltransferase attenuation leader peptide -
JM188_RS24995 () 77036..77740 + 705 WP_001067855.1 IS6 family transposase IS26 Transposase
JM188_RS25000 () 77806..78351 + 546 Protein_95 Tn3 family transposase TnpA_Tn3 Transposase
JM188_RS25005 () 78387..78802 - 416 Protein_96 IS1 family transposase -
JM188_RS25010 () 79051..79452 - 402 WP_001398199.1 type II toxin-antitoxin system toxin endoribonuclease PemK -
JM188_RS25015 () 79385..79642 - 258 WP_000557619.1 type II toxin-antitoxin system antitoxin PemI -
JM188_RS25020 () 79735..80388 - 654 WP_000616807.1 CPBP family intramembrane metalloprotease -
JM188_RS25025 () 81328..82185 - 858 WP_001617855.1 incFII family plasmid replication initiator RepA -
JM188_RS25030 () 82178..82252 - 75 WP_031943482.1 RepA leader peptide Tap -
JM188_RS25035 () 82249..82383 - 135 Protein_102 protein CopA/IncA -
JM188_RS25040 () 82489..82743 - 255 WP_000083850.1 replication regulatory protein RepA -
JM188_RS25045 () 83040..83174 - 135 WP_023144756.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
- () 83219..83279 + 61 NuclAT_1 - Antitoxin Detail
- () 83219..83279 + 61 NuclAT_1 - Antitoxin Detail
- () 83219..83279 + 61 NuclAT_1 - Antitoxin Detail
- () 83219..83279 + 61 NuclAT_1 - Antitoxin Detail
JM188_RS25050 () 83246..83532 - 287 Protein_105 DUF2726 domain-containing protein -
JM188_RS25055 () 84045..84257 - 213 WP_013023861.1 hypothetical protein -
JM188_RS25060 () 84388..84948 - 561 WP_000139341.1 fertility inhibition protein FinO -
JM188_RS25065 () 85003..85749 - 747 WP_000205725.1 conjugal transfer pilus acetylase TraX -
JM188_RS25070 () 85769..91039 - 5271 WP_032153768.1 Multifunctional conjugation protein TraI Relaxase
JM188_RS25075 () 91039..93246 - 2208 WP_021547900.1 type IV conjugative transfer system coupling protein TraD -
JM188_RS25080 () 93243..94022 - 780 WP_000199914.1 hypothetical protein -
JM188_RS25085 () 94225..94956 - 732 WP_000850429.1 complement resistance protein TraT -
JM188_RS25090 () 94988..95485 - 498 WP_000605862.1 entry exclusion protein -
JM188_RS25095 () 95504..98323 - 2820 WP_001007062.1 conjugal transfer mating pair stabilization protein TraG -
JM188_RS25100 () 98320..99693 - 1374 WP_000944328.1 conjugal transfer protein TraH -
JM188_RS25105 () 99680..100105 - 426 WP_001348758.1 F-type conjugal transfer protein TrbF -
JM188_RS25110 () 100053..100400 - 348 WP_071571857.1 P-type conjugative transfer protein TrbJ -
JM188_RS25115 () 100330..100875 - 546 WP_000059829.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
JM188_RS25120 () 100862..101146 - 285 WP_001617873.1 type-F conjugative transfer system pilin chaperone TraQ -
JM188_RS25125 () 101273..101593 - 321 WP_001348757.1 conjugal transfer protein TrbA -
JM188_RS25130 () 101641..102338 - 698 Protein_121 IS1 family transposase IS1G Transposase
JM188_RS25135 () 102493..103473 - 981 WP_000019450.1 IS5 family transposase ISKpn26 Transposase
JM188_RS25140 () 103603..104346 - 744 WP_001030401.1 type-F conjugative transfer system pilin assembly protein TraF -
JM188_RS25145 () 104339..104596 - 258 WP_000864347.1 conjugal transfer protein TrbE -
JM188_RS25150 () 104623..106473 - 1851 WP_000821866.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
JM188_RS25155 () 106470..107108 - 639 WP_001080259.1 type-F conjugative transfer system pilin assembly protein TrbC -
JM188_RS25160 () 107117..107422 - 306 WP_000224413.1 hypothetical protein -
JM188_RS25165 () 107452..108444 - 993 WP_000830190.1 conjugal transfer pilus assembly protein TraU -
JM188_RS25170 () 108441..109073 - 633 WP_001203727.1 type-F conjugative transfer system protein TraW -
JM188_RS25175 () 109070..109456 - 387 WP_000214084.1 type-F conjugative transfer system protein TrbI -
JM188_RS25180 () 109453..112080 - 2628 WP_001064258.1 type IV secretion system protein TraC -
JM188_RS25185 () 112240..112461 - 222 WP_001278694.1 conjugal transfer protein TraR -
JM188_RS25190 () 112596..113111 - 516 WP_000809886.1 type IV conjugative transfer system lipoprotein TraV -
JM188_RS25195 () 113111..113470 - 360 WP_001617876.1 conjugal transfer protein TrbD -
JM188_RS25200 () 113409..113996 - 588 WP_013023871.1 conjugal transfer protein TraP -
JM188_RS25205 () 113965..115416 - 1452 WP_000146687.1 conjugal transfer protein TraB -
JM188_RS25210 () 115416..116120 - 705 WP_148725207.1 type-F conjugative transfer system secretin TraK -
JM188_RS25215 () 116131..116697 - 567 WP_000399791.1 type IV conjugative transfer system protein TraE -
JM188_RS25220 () 116719..117030 - 312 WP_000012107.1 type IV conjugative transfer system protein TraL -
JM188_RS25225 () 117035..117397 - 363 WP_000338606.1 type IV conjugative transfer system pilin TraA -
JM188_RS25230 () 117431..117658 - 228 WP_001254388.1 conjugal transfer relaxosome protein TraY -
JM188_RS25235 () 117746..118423 - 678 WP_001348626.1 PAS domain-containing protein -
JM188_RS25240 () 118557..118940 - 384 WP_001151566.1 relaxosome protein TraM -
JM188_RS25245 () 119271..119873 + 603 WP_000243712.1 hypothetical protein VF
JM188_RS25250 () 120170..120991 - 822 WP_001234469.1 DUF945 domain-containing protein -
JM188_RS25255 () 121110..121397 - 288 WP_000107535.1 hypothetical protein -
JM188_RS25260 () 121422..121628 - 207 WP_000275859.1 hypothetical protein -
JM188_RS25265 () 122319..122477 - 159 WP_001312861.1 type I toxin-antitoxin system Hok family toxin Toxin Detail
- () 122521..122745 - 225 NuclAT_0 - Antitoxin Detail
- () 122521..122745 - 225 NuclAT_0 - Antitoxin Detail
- () 122521..122745 - 225 NuclAT_0 - Antitoxin Detail
- () 122521..122745 - 225 NuclAT_0 - Antitoxin Detail
JM188_RS25270 () 122557..122745 + 189 WP_001299721.1 hypothetical protein -
JM188_RS25275 () 122757..123476 - 720 WP_001276232.1 plasmid SOS inhibition protein A -
JM188_RS25280 () 123473..123907 - 435 WP_000845940.1 conjugation system SOS inhibitor PsiB -
JM188_RS25285 () 123962..125920 - 1959 WP_000117179.1 ParB/RepB/Spo0J family partition protein -
JM188_RS25290 () 125986..126219 - 234 WP_000005990.1 DUF905 family protein -
JM188_RS25295 () 126282..126821 - 540 WP_000290841.1 single-stranded DNA-binding protein -
JM188_RS25300 () 127464..127694 - 231 WP_021526513.1 hypothetical protein -
JM188_RS25305 () 127720..128283 - 564 WP_001348621.1 class I SAM-dependent methyltransferase -
JM188_RS25310 () 128331..129692 - 1362 WP_000170714.1 DUF3560 domain-containing protein -
JM188_RS25315 () 129744..129974 - 231 WP_000218642.1 hypothetical protein -
JM188_RS25320 () 131009..131200 - 192 WP_001027516.1 hypothetical protein -
JM188_RS25325 () 131197..131619 - 423 WP_000271753.1 DUF1380 family protein -
JM188_RS25330 () 131666..131968 - 303 WP_001671341.1 antirestriction protein -
JM188_RS25335 () 132508..133284 - 777 WP_001753849.1 hypothetical protein -
JM188_RS25340 () 133335..133769 - 435 WP_000274437.1 DUF1380 family protein -
JM188_RS25345 () 133783..134004 - 222 WP_001104873.1 hypothetical protein -
JM188_RS25350 () 134005..134688 - 684 WP_000086185.1 DNA methylase -
JM188_RS25355 () 134765..135069 - 305 Protein_166 hypothetical protein -
JM188_RS25360 () 135073..135975 - 903 WP_001348615.1 DUF1281 domain-containing protein -
JM188_RS25365 () 136842..137813 - 972 WP_000817036.1 ParB/RepB/Spo0J family plasmid partition protein -
JM188_RS25370 () 137813..138979 - 1167 WP_000772446.1 hypothetical protein VF
JM188_RS25375 () 139567..140322 - 756 WP_000852146.1 replication initiation protein RepE -
JM188_RS25380 () 141096..141902 - 807 WP_000016982.1 site-specific integrase -
JM188_RS25385 () 141903..142208 - 306 WP_001159868.1 type II toxin-antitoxin system toxin CcdB Toxin Detail
JM188_RS25390 () 142210..142428 - 219 WP_000813634.1 type II toxin-antitoxin system antitoxin CcdA -
JM188_RS25395 () 143136..144131 + 996 WP_000246636.1 hypothetical protein -
JM188_RS25400 () 144135..145067 + 933 WP_000991832.1 hypothetical protein -
JM188_RS25405 () 145204..145901 - 698 Protein_176 IS1 family transposase IS1G Transposase
JM188_RS25410 () 145957..148434 - 2478 Protein_177 HsdR family type I site-specific deoxyribonuclease -
JM188_RS25415 () 148556..149839 - 1284 WP_001617890.1 restriction endonuclease subunit S -
JM188_RS25420 () 149836..151392 - 1557 WP_001617892.1 type I restriction-modification system subunit M -
JM188_RS25425 () 151575..151796 + 222 WP_001190712.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
JM188_RS25430 () 151796..152176 + 381 WP_001216034.1 type II toxin-antitoxin system death-on-curing family toxin Toxin Detail
JM188_RS25435 () 152181..152360 + 180 WP_001513661.1 hypothetical protein -
JM188_RS25440 () 152388..152747 + 360 WP_001513660.1 hypothetical protein -
JM188_RS25445 () 152671..153084 + 414 Protein_184 IS3 family transposase ISLad1 Transposase
JM188_RS25450 () 153034..153351 - 318 WP_001513659.1 hypothetical protein -
JM188_RS25455 () 153579..154595 - 1017 WP_012372828.1 IS5 family transposase IS5D Transposase
JM188_RS25460 () 154803..156206 + 1404 WP_001373486.1 S-methylmethionine permease -
JM188_RS25465 () 156193..157125 + 933 WP_000081352.1 homocysteine S-methyltransferase -
JM188_RS25470 () 157234..157563 - 330 Protein_189 TOBE domain-containing protein -
JM188_RS25475 () 157579..158276 - 698 Protein_190 IS1 family transposase IS1R Transposase
JM188_RS25480 () 158334..158582 + 249 Protein_191 abortive infection family protein -
JM188_RS25485 () 158951..159682 - 732 WP_001617898.1 hypothetical protein -

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance