MGE detailed information
MGE type: Conjugative plasmid MGE length: 76615 bp
Accession: NZ_LR213457 Location: 1..76615 Organism: Shigella flexneri strain AUSMDU00008332 isolate AUSMDU00008332 Replicon: plasmid 3
Accession: NZ_LR213457 Location: 1..76615 Organism: Shigella flexneri strain AUSMDU00008332 isolate AUSMDU00008332 Replicon: plasmid 3
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| E0E35_RS25360 (1) | 1..963 | + | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
| E0E35_RS25365 (966) | 966..1316 | + | 351 | WP_000361389.1 | plasmid partitioning/stability family protein | - |
| E0E35_RS25370 (1439) | 1439..1720 | - | 282 | WP_001333089.1 | hypothetical protein | - |
| E0E35_RS25375 (1848) | 1848..2082 | - | 235 | Protein_3 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| E0E35_RS25390 (3579) | 3579..4316 | - | 738 | WP_013362818.1 | rRNA adenine N-6-methyltransferase | ARG |
| E0E35_RS25395 (4442) | 4442..4537 | - | 96 | WP_013362819.1 | 23S rRNA methyltransferase attenuation leader peptide | - |
| E0E35_RS25400 (4672) | 4672..5376 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| E0E35_RS25410 (5498) | 5498..6403 | + | 906 | WP_000219391.1 | hypothetical protein | ARG |
| E0E35_RS25415 (6400) | 6400..7638 | + | 1239 | WP_000004159.1 | macrolide resistance MFS transporter Mrx(A) | - |
| E0E35_RS25420 (7638) | 7638..8222 | + | 585 | WP_001137892.1 | macrolide-binding transcriptional repressor MphR(A) | - |
| E0E35_RS25435 (8715) | 8715..9479 | - | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| E0E35_RS26295 (9597) | 9597..9662 | - | 66 | Protein_12 | EAL domain-containing protein | - |
| E0E35_RS25445 (9706) | 9706..10011 | - | 306 | WP_000130000.1 | Transcriptional regulator | Relaxase |
| E0E35_RS25455 (10171) | 10171..10875 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| E0E35_RS25460 (11174) | 11174..12034 | + | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| E0E35_RS25465 (12181) | 12181..12462 | + | 282 | Protein_16 | transposase zinc-binding domain-containing protein | - |
| E0E35_RS25475 (12632) | 12632..13336 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| E0E35_RS25480 (13388) | 13388..13828 | + | 441 | Protein_18 | Tn3 family transposase TnpR_TnAs3 | Transposase |
| E0E35_RS25485 (13831) | 13831..16797 | + | 2967 | WP_001138064.1 | Tn3 family transposase TnpA_TnAs3 | Transposase |
| E0E35_RS25490 (16864) | 16864..17241 | + | 378 | WP_000656305.1 | GNAT family N-acetyltransferase | - |
| E0E35_RS25500 (18314) | 18314..18715 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| E0E35_RS25505 (18648) | 18648..18905 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| E0E35_RS25510 (18998) | 18998..19651 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| E0E35_RS27025 (19749) | 19749..19889 | - | 141 | WP_001333237.1 | hypothetical protein | - |
| E0E35_RS25520 (20590) | 20590..21447 | - | 858 | WP_016240488.1 | incFII family plasmid replication initiator RepA | - |
| E0E35_RS25525 (21440) | 21440..21514 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| E0E35_RS25535 (21759) | 21759..22007 | - | 249 | WP_000083839.1 | replication regulatory protein RepA | - |
| E0E35_RS25540 (22292) | 22292..22441 | - | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| - (22486) | 22486..22545 | + | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (22486) | 22486..22545 | + | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (22486) | 22486..22545 | + | 60 | NuclAT_1 | - | Antitoxin Detail |
| - (22486) | 22486..22545 | + | 60 | NuclAT_1 | - | Antitoxin Detail |
| E0E35_RS25550 (22688) | 22688..23161 | - | 474 | WP_016240489.1 | hypothetical protein | - |
| E0E35_RS25555 (23316) | 23316..23906 | - | 591 | WP_033807967.1 | DUF2726 domain-containing protein | - |
| E0E35_RS25560 (23944) | 23944..24153 | - | 210 | WP_001298565.1 | hemolysin expression modulator Hha | - |
| E0E35_RS25565 (24199) | 24199..24660 | - | 462 | WP_001233850.1 | thermonuclease family protein | - |
| E0E35_RS25570 (24906) | 24906..25118 | - | 213 | WP_001301409.1 | ANR family transcriptional regulator | - |
| E0E35_RS25575 (25250) | 25250..25810 | - | 561 | WP_033807966.1 | fertility inhibition protein FinO | - |
| E0E35_RS25580 (25865) | 25865..26611 | - | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| E0E35_RS25585 (26631) | 26631..31901 | - | 5271 | WP_033807965.1 | Multifunctional conjugation protein TraI | Relaxase |
| E0E35_RS25590 (31901) | 31901..34207 | - | 2307 | WP_134797816.1 | Coupling protein TraD | VF |
| E0E35_RS25595 (34258) | 34258..34995 | - | 738 | WP_012881122.1 | hypothetical protein | - |
| E0E35_RS25600 (35198) | 35198..35929 | - | 732 | WP_012881123.1 | conjugal transfer complement resistance protein TraT | - |
| E0E35_RS25605 (35943) | 35943..36452 | - | 510 | WP_000628111.1 | conjugal transfer entry exclusion protein TraS | - |
| E0E35_RS25610 (36449) | 36449..39274 | - | 2826 | WP_033807963.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| E0E35_RS25615 (39271) | 39271..40644 | - | 1374 | WP_033807962.1 | conjugal transfer pilus assembly protein TraH | - |
| E0E35_RS25620 (40631) | 40631..41023 | - | 393 | WP_000659962.1 | F-type conjugal transfer protein TrbF | - |
| E0E35_RS25625 (41004) | 41004..41351 | - | 348 | WP_071571857.1 | P-type conjugative transfer protein TrbJ | - |
| E0E35_RS25630 (41281) | 41281..41826 | - | 546 | WP_000059829.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| E0E35_RS25635 (41813) | 41813..42097 | - | 285 | WP_000624107.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| E0E35_RS25640 (42178) | 42178..42513 | + | 336 | WP_001620807.1 | hypothetical protein | - |
| E0E35_RS25645 (42494) | 42494..42835 | - | 342 | WP_000556795.1 | conjugal transfer protein TrbA | - |
| E0E35_RS25650 (42849) | 42849..43592 | - | 744 | WP_001030371.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| E0E35_RS25655 (43585) | 43585..43842 | - | 258 | WP_033807961.1 | conjugal transfer protein TrbE | - |
| E0E35_RS25660 (43869) | 43869..45773 | - | 1905 | WP_225620370.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| E0E35_RS25665 (46009) | 46009..46389 | - | 381 | WP_001462111.1 | hypothetical protein | - |
| E0E35_RS25670 (46386) | 46386..47024 | - | 639 | WP_033807960.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| E0E35_RS25675 (47033) | 47033..47338 | - | 306 | WP_000224418.1 | hypothetical protein | - |
| E0E35_RS25680 (47368) | 47368..48360 | - | 993 | WP_000830849.1 | conjugal transfer pilus assembly protein TraU | - |
| E0E35_RS25685 (48357) | 48357..48989 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| E0E35_RS25690 (48986) | 48986..49372 | - | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| E0E35_RS25695 (49369) | 49369..51999 | - | 2631 | WP_000069772.1 | type IV secretion system protein TraC | - |
| E0E35_RS25700 (52125) | 52125..52472 | - | 348 | WP_000836682.1 | hypothetical protein | - |
| E0E35_RS25705 (52500) | 52500..52718 | - | 219 | WP_033807959.1 | hypothetical protein | - |
| E0E35_RS25710 (52817) | 52817..53290 | - | 474 | WP_033807958.1 | hypothetical protein | - |
| E0E35_RS25715 (53283) | 53283..53696 | - | 414 | WP_000549589.1 | hypothetical protein | - |
| E0E35_RS25720 (53689) | 53689..53910 | - | 222 | WP_001278683.1 | conjugal transfer protein TraR | - |
| E0E35_RS25725 (54045) | 54045..54560 | - | 516 | WP_000809881.1 | type IV conjugative transfer system lipoprotein TraV | - |
| E0E35_RS25730 (54557) | 54557..54877 | - | 321 | WP_012881128.1 | conjugal transfer protein TrbD | - |
| E0E35_RS25735 (54864) | 54864..55454 | - | 591 | WP_000002784.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| E0E35_RS25740 (55444) | 55444..56871 | - | 1428 | WP_033807957.1 | F-type conjugal transfer pilus assembly protein TraB | - |
| E0E35_RS25745 (56871) | 56871..57599 | - | 729 | WP_001230769.1 | type-F conjugative transfer system secretin TraK | - |
| E0E35_RS25750 (57586) | 57586..58152 | - | 567 | WP_000399780.1 | type IV conjugative transfer system protein TraE | - |
| E0E35_RS25755 (58174) | 58174..58485 | - | 312 | WP_000012113.1 | type IV conjugative transfer system protein TraL | - |
| E0E35_RS25760 (58500) | 58500..58859 | - | 360 | WP_001098994.1 | type IV conjugative transfer system pilin TraA | - |
| E0E35_RS25765 (58893) | 58893..59120 | - | 228 | WP_000589556.1 | conjugal transfer relaxosome protein TraY | - |
| E0E35_RS25770 (59240) | 59240..59887 | - | 648 | WP_000332523.1 | transcriptional regulator TraJ family protein | - |
| E0E35_RS25775 (60079) | 60079..60462 | - | 384 | WP_001151529.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| E0E35_RS25780 (60795) | 60795..61385 | + | 591 | WP_000252683.1 | hypothetical protein | VF |
| E0E35_RS25785 (61682) | 61682..62503 | - | 822 | WP_001234445.1 | DUF932 domain-containing protein | - |
| E0E35_RS25790 (62614) | 62614..62910 | - | 297 | WP_001272251.1 | hypothetical protein | - |
| E0E35_RS25800 (63210) | 63210..63506 | + | 297 | Protein_79 | hypothetical protein | - |
| E0E35_RS25805 (63825) | 63825..63950 | - | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| E0E35_RS27030 (63892) | 63892..64041 | - | 150 | Protein_81 | plasmid maintenance protein Mok | - |
| E0E35_RS25810 (64063) | 64063..64242 | + | 180 | WP_001334662.1 | hypothetical protein | - |
| - (64027) | 64027..64251 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (64027) | 64027..64251 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (64027) | 64027..64251 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - (64027) | 64027..64251 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| E0E35_RS25815 (64220) | 64220..64982 | - | 763 | Protein_83 | plasmid SOS inhibition protein A | - |
| E0E35_RS25820 (64979) | 64979..65413 | - | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| E0E35_RS25825 (65468) | 65468..67426 | - | 1959 | WP_112324844.1 | ParB/RepB/Spo0J family partition protein | - |
| E0E35_RS25830 (67490) | 67490..67723 | - | 234 | WP_000005971.1 | DUF905 domain-containing protein | - |
| E0E35_RS25835 (67779) | 67779..68300 | - | 522 | WP_033807850.1 | single-stranded DNA-binding protein | - |
| E0E35_RS27035 (68599) | 68599..69042 | + | 444 | Protein_88 | hypothetical protein | - |
| E0E35_RS25855 (69128) | 69128..69691 | - | 564 | WP_016240496.1 | class I SAM-dependent methyltransferase | - |
| E0E35_RS25860 (69738) | 69738..71099 | - | 1362 | WP_000170671.1 | DUF3560 domain-containing protein | - |
| E0E35_RS25865 (71151) | 71151..71381 | - | 231 | WP_000218647.1 | hypothetical protein | - |
| E0E35_RS27040 (72050) | 72050..72205 | - | 156 | WP_159420149.1 | hypothetical protein | - |
| E0E35_RS25875 (72419) | 72419..72610 | - | 192 | WP_001027493.1 | hypothetical protein | - |
| E0E35_RS25880 (72607) | 72607..73029 | - | 423 | WP_000271762.1 | DUF1380 family protein | - |
| E0E35_RS25885 (73076) | 73076..73501 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| E0E35_RS26300 (73919) | 73919..74695 | - | 777 | WP_001383963.1 | hypothetical protein | - |
| E0E35_RS25905 (74746) | 74746..75180 | - | 435 | WP_000274503.1 | DUF1380 family protein | - |
| E0E35_RS25910 (75194) | 75194..75415 | - | 222 | WP_001104881.1 | hypothetical protein | - |
| E0E35_RS25915 (75416) | 75416..76099 | - | 684 | WP_000085883.1 | DNA methylase | - |
| E0E35_RS25925 (76176) | 76176..76469 | - | 294 | WP_032146011.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|