MGE detailed information
MGE type: Conjugative plasmid MGE length: 82887 bp
Accession: NZ_LR213453 Location: 1..82887 Organism: Shigella flexneri strain AUSMDU00008355 isolate AUSMDU00008355 Replicon: plasmid 2
Accession: NZ_LR213453 Location: 1..82887 Organism: Shigella flexneri strain AUSMDU00008355 isolate AUSMDU00008355 Replicon: plasmid 2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| E0E33_RS22830 () | 1..963 | + | 963 | WP_000959884.1 | plasmid segregation protein ParM | - |
| E0E33_RS22835 () | 966..1316 | + | 351 | WP_000361389.1 | plasmid partitioning/stability family protein | - |
| E0E33_RS22840 () | 1439..1720 | - | 282 | WP_001333089.1 | hypothetical protein | - |
| E0E33_RS22845 () | 1848..2082 | - | 235 | Protein_3 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| E0E33_RS22860 () | 3531..4228 | - | 698 | Protein_4 | IS1 family transposase IS1R | Transposase |
| E0E33_RS24150 () | 4876..5046 | - | 171 | WP_170852050.1 | rRNA adenine methyltransferase | - |
| E0E33_RS22870 () | 4991..5728 | - | 738 | WP_013362818.1 | rRNA adenine N-6-methyltransferase | ARG |
| E0E33_RS22875 () | 5854..5949 | - | 96 | WP_013362819.1 | 23S rRNA methyltransferase attenuation leader peptide | - |
| E0E33_RS22880 () | 6084..6788 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| E0E33_RS22890 () | 6910..7815 | + | 906 | WP_000219391.1 | hypothetical protein | ARG |
| E0E33_RS22895 () | 7812..9050 | + | 1239 | WP_000004159.1 | MFS transporter | - |
| E0E33_RS22900 () | 9050..9634 | + | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| E0E33_RS22915 () | 10127..10891 | - | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| E0E33_RS24155 () | 11009..11074 | - | 66 | Protein_13 | EAL domain-containing protein | - |
| E0E33_RS22925 () | 11118..11423 | - | 306 | WP_000130000.1 | Transcriptional regulator | Relaxase |
| E0E33_RS22930 () | 11434..12639 | - | 1206 | WP_000184001.1 | chromate efflux transporter | - |
| E0E33_RS22935 () | 12795..12998 | - | 204 | WP_000376616.1 | hypothetical protein | - |
| E0E33_RS22945 () | 13126..13965 | - | 840 | WP_000259031.1 | Dihydropteroate synthase | ARG |
| E0E33_RS22950 () | 13959..14306 | - | 348 | WP_000679427.1 | Multidrug transporter EmrE | ARG |
| E0E33_RS22955 () | 14512..15300 | - | 789 | WP_000503573.1 | Streptomycin 3''-adenylyltransferase | ARG |
| E0E33_RS22960 () | 15431..15904 | - | 474 | WP_001389366.1 | trimethoprim-resistant dihydrofolate reductase DfrA17 | - |
| E0E33_RS22965 () | 16062..17075 | + | 1014 | WP_000845048.1 | IS91 family transposase ISAzo26 | Transposase |
| E0E33_RS22975 () | 17278..17628 | + | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| E0E33_RS22980 () | 17827..18531 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| E0E33_RS22985 () | 18597..19028 | + | 432 | Protein_24 | Tn3 family transposase TnpR_Tn3 | Transposase |
| E0E33_RS22990 () | 19211..20071 | + | 861 | WP_021526512.1 | Beta-lactamase TEM | ARG |
| E0E33_RS22995 () | 20221..20319 | - | 99 | Protein_26 | IS1 family transposase | - |
| E0E33_RS23000 () | 20348..21658 | - | 1311 | WP_001262765.1 | DUF262 domain-containing protein | - |
| E0E33_RS23005 () | 21943..22344 | - | 402 | WP_001398199.1 | type II toxin-antitoxin system toxin endoribonuclease PemK | - |
| E0E33_RS23010 () | 22277..22534 | - | 258 | WP_000557619.1 | type II toxin-antitoxin system antitoxin PemI | - |
| E0E33_RS23015 () | 22627..23280 | - | 654 | WP_000616807.1 | CPBP family intramembrane metalloprotease | - |
| E0E33_RS23025 () | 24219..25076 | - | 858 | WP_016240488.1 | incFII family plasmid replication initiator RepA | - |
| E0E33_RS23030 () | 25069..25143 | - | 75 | WP_001365705.1 | RepA leader peptide Tap | - |
| E0E33_RS23040 () | 25388..25636 | - | 249 | WP_000083839.1 | replication regulatory protein RepA | - |
| E0E33_RS23045 () | 25921..26070 | - | 150 | WP_001312851.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 26115..26174 | + | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 26115..26174 | + | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 26115..26174 | + | 60 | NuclAT_1 | - | Antitoxin Detail |
| - () | 26115..26174 | + | 60 | NuclAT_1 | - | Antitoxin Detail |
| E0E33_RS23055 () | 26317..26790 | - | 474 | WP_016240489.1 | hypothetical protein | - |
| E0E33_RS23060 () | 26945..27535 | - | 591 | WP_033807967.1 | DUF2726 domain-containing protein | - |
| E0E33_RS23065 () | 27573..27782 | - | 210 | WP_001298565.1 | hemolysin expression modulator Hha | - |
| E0E33_RS23070 () | 27828..28289 | - | 462 | WP_001233850.1 | thermonuclease family protein | - |
| E0E33_RS23075 () | 28535..28747 | - | 213 | WP_001301409.1 | ANR family transcriptional regulator | - |
| E0E33_RS23080 () | 28879..29439 | - | 561 | WP_033807966.1 | fertility inhibition protein FinO | - |
| E0E33_RS23085 () | 29494..30240 | - | 747 | WP_000205718.1 | conjugal transfer pilus acetylase TraX | - |
| E0E33_RS23090 () | 30260..35530 | - | 5271 | WP_033807965.1 | Multifunctional conjugation protein TraI | Relaxase |
| E0E33_RS23095 () | 35530..37818 | - | 2289 | WP_130862258.1 | Coupling protein TraD | VF |
| E0E33_RS23100 () | 37869..38606 | - | 738 | WP_012881122.1 | hypothetical protein | - |
| E0E33_RS23105 () | 38809..39540 | - | 732 | WP_012881123.1 | complement resistance protein TraT | - |
| E0E33_RS23110 () | 39554..40063 | - | 510 | WP_000628111.1 | conjugal transfer entry exclusion protein TraS | - |
| E0E33_RS23115 () | 40060..42885 | - | 2826 | WP_033807963.1 | conjugal transfer mating pair stabilization protein TraG | - |
| E0E33_RS23120 () | 42882..44255 | - | 1374 | WP_033807962.1 | conjugal transfer protein TraH | - |
| E0E33_RS23125 () | 44242..44667 | - | 426 | WP_001348758.1 | F-type conjugal transfer protein TrbF | - |
| E0E33_RS23130 () | 44615..44962 | - | 348 | WP_071571857.1 | P-type conjugative transfer protein TrbJ | - |
| E0E33_RS23135 () | 44892..45437 | - | 546 | WP_000059829.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| E0E33_RS23140 () | 45424..45708 | - | 285 | WP_000624107.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| E0E33_RS23145 () | 45789..46124 | + | 336 | WP_001620807.1 | hypothetical protein | - |
| E0E33_RS23150 () | 46105..46446 | - | 342 | WP_000556795.1 | conjugal transfer protein TrbA | - |
| E0E33_RS23155 () | 46460..47203 | - | 744 | WP_001030371.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| E0E33_RS23160 () | 47196..47453 | - | 258 | WP_033807961.1 | conjugal transfer protein TrbE | - |
| E0E33_RS23165 () | 47480..49309 | - | 1830 | WP_033807969.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| E0E33_RS23170 () | 49620..50000 | - | 381 | WP_001462111.1 | hypothetical protein | - |
| E0E33_RS23175 () | 49997..50635 | - | 639 | WP_033807960.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| E0E33_RS23180 () | 50644..50949 | - | 306 | WP_000224418.1 | hypothetical protein | - |
| E0E33_RS23185 () | 50979..51971 | - | 993 | WP_000830849.1 | conjugal transfer pilus assembly protein TraU | - |
| E0E33_RS23190 () | 51968..52600 | - | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| E0E33_RS23195 () | 52597..52983 | - | 387 | WP_000214084.1 | type-F conjugative transfer system protein TrbI | - |
| E0E33_RS23200 () | 52980..55610 | - | 2631 | WP_000069772.1 | type IV secretion system protein TraC | - |
| E0E33_RS23205 () | 55736..56083 | - | 348 | WP_000836682.1 | hypothetical protein | - |
| E0E33_RS23210 () | 56111..56329 | - | 219 | WP_033807959.1 | hypothetical protein | - |
| E0E33_RS23215 () | 56428..56901 | - | 474 | WP_033807958.1 | hypothetical protein | - |
| E0E33_RS23220 () | 56894..57307 | - | 414 | WP_000549589.1 | hypothetical protein | - |
| E0E33_RS23225 () | 57300..57521 | - | 222 | WP_001278683.1 | conjugal transfer protein TraR | - |
| E0E33_RS23230 () | 57656..58171 | - | 516 | WP_000809881.1 | type IV conjugative transfer system lipoprotein TraV | - |
| E0E33_RS23235 () | 58168..58536 | - | 369 | WP_001681801.1 | conjugal transfer protein TrbD | - |
| E0E33_RS23240 () | 58475..59065 | - | 591 | WP_000002784.1 | conjugal transfer protein TraP | - |
| E0E33_RS23245 () | 59055..60482 | - | 1428 | WP_033807957.1 | conjugal transfer protein TraB | - |
| E0E33_RS23250 () | 60482..61210 | - | 729 | WP_001230769.1 | type-F conjugative transfer system secretin TraK | - |
| E0E33_RS23255 () | 61197..61763 | - | 567 | WP_000399780.1 | type IV conjugative transfer system protein TraE | - |
| E0E33_RS23260 () | 61785..62096 | - | 312 | WP_000012113.1 | type IV conjugative transfer system protein TraL | - |
| E0E33_RS23265 () | 62111..62470 | - | 360 | WP_001098994.1 | type IV conjugative transfer system pilin TraA | - |
| E0E33_RS23270 () | 62504..62743 | - | 240 | WP_042018283.1 | conjugal transfer relaxosome protein TraY | - |
| E0E33_RS23275 () | 62851..63498 | - | 648 | WP_128867105.1 | transcriptional regulator TraJ family protein | - |
| E0E33_RS23280 () | 63690..64073 | - | 384 | WP_001151529.1 | relaxosome protein TraM | - |
| E0E33_RS23285 () | 64406..64996 | + | 591 | WP_000252683.1 | hypothetical protein | VF |
| E0E33_RS23290 () | 65293..66114 | - | 822 | WP_001234445.1 | DUF945 domain-containing protein | - |
| E0E33_RS23295 () | 66225..66521 | - | 297 | WP_001272251.1 | hypothetical protein | - |
| E0E33_RS23305 () | 66821..67198 | + | 378 | Protein_84 | hypothetical protein | - |
| E0E33_RS23310 () | 67436..67594 | - | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 67638..67862 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 67638..67862 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 67638..67862 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 67638..67862 | - | 225 | NuclAT_0 | - | Antitoxin Detail |
| E0E33_RS23315 () | 67674..67853 | + | 180 | WP_001334662.1 | hypothetical protein | - |
| E0E33_RS23320 () | 67874..68593 | - | 720 | WP_033807739.1 | plasmid SOS inhibition protein A | - |
| E0E33_RS23325 () | 68590..69024 | - | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| E0E33_RS23330 () | 69079..71037 | - | 1959 | WP_112324844.1 | ParB/RepB/Spo0J family partition protein | - |
| E0E33_RS23335 () | 71101..71334 | - | 234 | WP_000005971.1 | DUF905 domain-containing protein | - |
| E0E33_RS23340 () | 71390..71869 | - | 480 | WP_130862260.1 | single-stranded DNA-binding protein | - |
| E0E33_RS23345 () | 72019..73920 | - | 1902 | WP_000936285.1 | group II intron reverse transcriptase/maturase | - |
| E0E33_RS23360 () | 75400..75963 | - | 564 | WP_016240496.1 | class I SAM-dependent methyltransferase | - |
| E0E33_RS23365 () | 76010..77371 | - | 1362 | WP_000170671.1 | DUF3560 domain-containing protein | - |
| E0E33_RS23370 () | 77423..77653 | - | 231 | WP_000218647.1 | hypothetical protein | - |
| E0E33_RS23380 () | 78691..78882 | - | 192 | WP_001027493.1 | hypothetical protein | - |
| E0E33_RS23385 () | 78879..79301 | - | 423 | WP_000271762.1 | DUF1380 family protein | - |
| E0E33_RS23390 () | 79348..79773 | - | 426 | WP_001198928.1 | antirestriction protein | - |
| E0E33_RS24160 () | 80191..80967 | - | 777 | WP_001383963.1 | hypothetical protein | - |
| E0E33_RS23410 () | 81018..81452 | - | 435 | WP_000274503.1 | DUF1380 family protein | - |
| E0E33_RS23415 () | 81466..81687 | - | 222 | WP_001104881.1 | hypothetical protein | - |
| E0E33_RS23420 () | 81688..82371 | - | 684 | WP_000085883.1 | DNA methylase | - |
| E0E33_RS23430 () | 82448..82741 | - | 294 | WP_032146011.1 | hypothetical protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|