MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 167946 bp
Accession: NZ_LR135236 Location: 1..167946 Organism: Enterococcus faecium isolate E7067 Replicon: plasmid 2
Accession: NZ_LR135236 Location: 1..167946 Organism: Enterococcus faecium isolate E7067 Replicon: plasmid 2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EQB63_RS14150 () | 1..1041 | + | 1041 | WP_002326172.1 | replication initiator protein A | - |
| EQB63_RS14155 () | 1865..2197 | + | 333 | WP_002323647.1 | hypothetical protein | - |
| EQB63_RS14160 () | 2816..3157 | + | 342 | WP_002295674.1 | DUF5406 domain-containing protein | - |
| EQB63_RS14165 () | 3394..4644 | - | 1251 | WP_002297404.1 | IS110 family transposase ISSpn10 | Transposase |
| EQB63_RS14170 () | 5054..7426 | + | 2373 | WP_126341262.1 | hypothetical protein | - |
| EQB63_RS14175 () | 7487..8947 | + | 1461 | WP_010733685.1 | toprim domain-containing protein | - |
| EQB63_RS14180 () | 8958..11163 | + | 2206 | Protein_6 | DNA topoisomerase III | - |
| EQB63_RS16425 () | 11179..11328 | + | 150 | WP_002326517.1 | hypothetical protein | - |
| EQB63_RS14185 () | 11403..11996 | + | 594 | WP_127836240.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | - |
| EQB63_RS14190 () | 12009..12908 | + | 900 | WP_002326884.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
| EQB63_RS14195 () | 12911..13384 | + | 474 | WP_127836241.1 | single-stranded DNA-binding protein | - |
| EQB63_RS14200 () | 13750..14010 | + | 261 | WP_002296240.1 | hypothetical protein | - |
| EQB63_RS14205 () | 14455..14661 | + | 207 | WP_002325537.1 | hypothetical protein | - |
| EQB63_RS14210 () | 14709..14912 | + | 204 | WP_110300627.1 | hypothetical protein | - |
| EQB63_RS14215 () | 14928..15365 | + | 438 | WP_126341263.1 | hypothetical protein | - |
| EQB63_RS14220 () | 15358..16065 | + | 708 | WP_002332739.1 | hypothetical protein | - |
| EQB63_RS14230 () | 16445..16675 | + | 231 | WP_126341264.1 | hypothetical protein | - |
| EQB63_RS14235 () | 16901..17164 | + | 264 | WP_002287514.1 | hypothetical protein | Antitoxin Detail |
| EQB63_RS14240 () | 17158..17508 | + | 351 | WP_002321032.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin Detail |
| EQB63_RS14245 () | 17532..18146 | - | 615 | WP_002318230.1 | Tn3 family transposase TnpR_TnAs2 | Transposase |
| EQB63_RS14250 () | 18460..18882 | + | 423 | WP_002288787.1 | hypothetical protein | - |
| EQB63_RS14255 () | 18892..19095 | + | 204 | WP_002299573.1 | hypothetical protein | - |
| EQB63_RS14260 () | 19306..19896 | + | 591 | WP_065305702.1 | Tn3 family transposase TnBth3 | Transposase |
| EQB63_RS14265 () | 20049..20663 | + | 615 | WP_065305703.1 | Tn3 family transposase TnpR_ISPa40 | Transposase |
| EQB63_RS14270 () | 20687..21856 | + | 1170 | Protein_24 | hypothetical protein | - |
| EQB63_RS14275 () | 21848..22807 | - | 960 | WP_002297271.1 | IS30 family transposase IS6770 | Transposase |
| EQB63_RS14280 () | 23566..23903 | + | 338 | Protein_26 | recombinase family protein | - |
| EQB63_RS14285 () | 23903..25026 | + | 1124 | Protein_27 | DNA topoisomerase | - |
| EQB63_RS14295 () | 25313..25552 | - | 240 | Protein_28 | HAD family hydrolase | - |
| EQB63_RS14300 () | 25613..26775 | + | 1163 | WP_086956687.1 | IS3 family transposase IS1485 | Transposase |
| EQB63_RS14305 () | 26881..27528 | - | 648 | WP_106018936.1 | HAD family hydrolase | - |
| EQB63_RS14310 () | 27533..28300 | - | 768 | WP_002345826.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| EQB63_RS14315 () | 28789..29214 | + | 426 | WP_002290555.1 | galactose-6-phosphate isomerase subunit LacA | - |
| EQB63_RS14320 () | 29231..29746 | + | 516 | WP_070828487.1 | galactose-6-phosphate isomerase subunit LacB | - |
| EQB63_RS14325 () | 29757..30689 | + | 933 | WP_070828488.1 | tagatose-6-phosphate kinase | - |
| EQB63_RS14330 () | 30692..31672 | + | 981 | WP_002290551.1 | tagatose-bisphosphate aldolase | - |
| EQB63_RS14335 () | 31700..32017 | + | 318 | WP_002290550.1 | PTS lactose/cellobiose transporter subunit IIA | - |
| EQB63_RS14340 () | 32017..33723 | + | 1707 | WP_070828490.1 | lactose-specific PTS transporter subunit EIIC | - |
| EQB63_RS14345 () | 33870..35276 | + | 1407 | WP_002290548.1 | 6-phospho-beta-galactosidase | - |
| EQB63_RS16430 () | 35399..35572 | + | 174 | WP_164855624.1 | DUF3884 family protein | - |
| EQB63_RS14355 () | 35593..36492 | + | 900 | WP_002345823.1 | aldose 1-epimerase family protein | - |
| EQB63_RS14360 () | 36898..37302 | + | 405 | WP_002287522.1 | IS200-IS605 family transposase ISEfa4 | Transposase |
| EQB63_RS14365 () | 37319..38467 | + | 1149 | WP_002287525.1 | IS200-IS605 family transposase ISEfa4 | Transposase |
| EQB63_RS14370 () | 38801..40414 | + | 1614 | WP_126341265.1 | ATP-binding protein | - |
| EQB63_RS14375 () | 40417..41106 | + | 690 | WP_126341266.1 | RloB family protein | - |
| EQB63_RS14380 () | 41095..42390 | - | 1296 | WP_127822560.1 | ISL3 family transposase IS1251 | Transposase |
| EQB63_RS14385 () | 42922..43476 | + | 555 | WP_002301108.1 | tyrosine-type recombinase/integrase | - |
| EQB63_RS16435 () | 43730..44310 | + | 581 | Protein_47 | hypothetical protein | - |
| EQB63_RS14395 () | 44353..44559 | + | 207 | WP_077974490.1 | hypothetical protein | - |
| EQB63_RS14400 () | 44781..45638 | - | 858 | WP_172595658.1 | IS982 family transposase ISEfm1 | Transposase |
| EQB63_RS14405 () | 45885..47075 | + | 1191 | Protein_50 | IS256 family transposase ISLgar5 | Transposase |
| EQB63_RS14410 () | 47494..48693 | + | 1200 | WP_073466303.1 | MFS transporter | - |
| EQB63_RS14415 () | 49228..50390 | + | 1163 | WP_086956687.1 | IS3 family transposase IS1485 | Transposase |
| EQB63_RS14420 () | 50557..51315 | - | 759 | WP_073466287.1 | MurR/RpiR family transcriptional regulator | - |
| EQB63_RS14425 () | 51499..52407 | + | 909 | WP_077974480.1 | IS982 family transposase ISEfm1 | Transposase |
| EQB63_RS14430 () | 52532..53467 | + | 936 | WP_073466326.1 | 1-phosphofructokinase | - |
| EQB63_RS14435 () | 53464..54909 | + | 1446 | WP_073466327.1 | PTS fructose transporter subunit IIBC | - |
| EQB63_RS14440 () | 54937..55392 | + | 456 | WP_002336650.1 | fructose PTS transporter subunit IIA | - |
| EQB63_RS14445 () | 55411..56385 | + | 975 | WP_005880910.1 | tagatose-bisphosphate aldolase | - |
| EQB63_RS14450 () | 56495..56980 | - | 486 | Protein_59 | TetR family transcriptional regulator C-terminal domain-containing protein | - |
| EQB63_RS14455 () | 57140..57823 | - | 684 | WP_164855625.1 | IS6 family transposase IS1216E | Transposase |
| EQB63_RS14460 () | 57894..58160 | + | 267 | Protein_61 | LacI family DNA-binding transcriptional regulator | - |
| EQB63_RS14465 () | 58405..59430 | + | 1026 | WP_002290378.1 | LacI family DNA-binding transcriptional regulator | - |
| EQB63_RS14470 () | 59724..60833 | + | 1110 | WP_002335321.1 | sugar ABC transporter substrate-binding protein | - |
| EQB63_RS14475 () | 60916..61812 | + | 897 | Protein_64 | sugar ABC transporter permease | - |
| EQB63_RS14480 () | 61828..62652 | + | 825 | WP_047929206.1 | carbohydrate ABC transporter permease | - |
| EQB63_RS14485 () | 62684..63994 | + | 1311 | WP_002341308.1 | alpha-glucosidase/alpha-galactosidase | - |
| EQB63_RS14490 () | 64142..65401 | + | 1260 | WP_002290371.1 | extracellular solute-binding protein | - |
| EQB63_RS14495 () | 65411..66283 | + | 873 | WP_002290370.1 | sugar ABC transporter permease | - |
| EQB63_RS14500 () | 66295..67125 | + | 831 | WP_002290368.1 | carbohydrate ABC transporter permease | - |
| EQB63_RS14505 () | 67165..69348 | + | 2184 | WP_002324534.1 | alpha-galactosidase | - |
| EQB63_RS14510 () | 69409..70629 | + | 1221 | WP_073466380.1 | oligo-1,6-glucosidase | - |
| EQB63_RS14515 () | 70626..72086 | + | 1461 | WP_002324531.1 | sucrose phosphorylase | - |
| EQB63_RS14520 () | 72163..73269 | + | 1107 | Protein_73 | IS4 family transposase IS641 | Transposase |
| EQB63_RS14525 () | 73591..73800 | + | 210 | WP_002290357.1 | DUF3173 domain-containing protein | - |
| EQB63_RS14530 () | 73793..73942 | + | 150 | WP_002290356.1 | hypothetical protein | - |
| EQB63_RS14535 () | 74096..74761 | + | 666 | WP_002324528.1 | site-specific integrase | - |
| EQB63_RS14540 () | 75045..76130 | - | 1086 | WP_002290352.1 | tyrosine recombinase XerS | - |
| EQB63_RS14545 () | 76464..76697 | + | 234 | WP_002290351.1 | addiction module antitoxin | - |
| EQB63_RS14550 () | 76694..77101 | + | 408 | WP_002329899.1 | type II toxin-antitoxin system death-on-curing family toxin | - |
| EQB63_RS14560 () | 78238..78756 | - | 519 | WP_002287870.1 | ClbS/DfsB family four-helix bundle protein | - |
| EQB63_RS14565 () | 79123..79371 | + | 249 | WP_002305874.1 | IS3 family transposase ISSag5 | Transposase |
| EQB63_RS14575 () | 79935..81097 | + | 1163 | WP_127822562.1 | IS3 family transposase IS1485 | Transposase |
| EQB63_RS14580 () | 81388..81498 | + | 111 | Protein_83 | transposase | - |
| EQB63_RS14585 () | 81595..82071 | - | 477 | WP_065305738.1 | PTS glucose transporter subunit IIA | - |
| EQB63_RS14590 () | 82084..83586 | - | 1503 | WP_002289252.1 | PTS transporter subunit EIIC | - |
| EQB63_RS14595 () | 83600..84289 | - | 690 | WP_002289253.1 | N-acetylmannosamine-6-phosphate 2-epimerase | - |
| EQB63_RS14600 () | 84451..85269 | + | 819 | WP_002289254.1 | MurR/RpiR family transcriptional regulator | - |
| EQB63_RS14605 () | 85613..85789 | - | 177 | Protein_88 | foldase PrsA domain protein | - |
| EQB63_RS14610 () | 86344..87522 | + | 1179 | WP_065305739.1 | IS256 family transposase ISEfm2 | Transposase |
| EQB63_RS16440 () | 87640..87867 | - | 228 | WP_131792840.1 | hypothetical protein | - |
| EQB63_RS16500 () | 88233..89032 | + | 800 | Protein_91 | ISL3 family transposase | - |
| EQB63_RS14630 () | 89369..90619 | - | 1251 | WP_002330944.1 | PTS sugar transporter subunit IIC | - |
| EQB63_RS14635 () | 90638..91564 | - | 927 | WP_002298736.1 | PEP phosphonomutase | - |
| EQB63_RS14640 () | 91643..92638 | - | 996 | WP_002301128.1 | tagatose-bisphosphate aldolase | - |
| EQB63_RS14645 () | 92654..93823 | - | 1170 | WP_002301130.1 | SIS domain-containing protein | - |
| EQB63_RS14650 () | 93839..94573 | - | 735 | WP_002301131.1 | GntR family transcriptional regulator | - |
| EQB63_RS14660 () | 97075..98367 | - | 1293 | WP_002301811.1 | IS256 family transposase ISBsu2 | Transposase |
| EQB63_RS14665 () | 98641..98901 | - | 261 | WP_002313174.1 | hypothetical protein | - |
| EQB63_RS14670 () | 99152..100330 | + | 1179 | WP_002346943.1 | IS256 family transposase ISEf1 | Transposase |
| EQB63_RS14675 () | 100682..100978 | + | 297 | WP_073120200.1 | IS3 family transposase ISEfa8 | Transposase |
| EQB63_RS14680 () | 100901..101725 | - | 825 | Protein_102 | IS3 family transposase ISEfa8 | Transposase |
| EQB63_RS14685 () | 101927..102322 | - | 396 | WP_002287876.1 | aspartate 1-decarboxylase | - |
| EQB63_RS14690 () | 102332..103180 | - | 849 | WP_002287875.1 | pantoate--beta-alanine ligase | - |
| EQB63_RS14695 () | 103195..104022 | - | 828 | WP_002287874.1 | 3-methyl-2-oxobutanoate hydroxymethyltransferase | - |
| EQB63_RS14700 () | 104034..104894 | - | 861 | WP_002349114.1 | Rossmann-like and DUF2520 domain-containing protein | - |
| EQB63_RS14705 () | 105132..106301 | + | 1170 | WP_002300493.1 | IS256 family transposase ISEfa13 | Transposase |
| EQB63_RS14710 () | 106641..107321 | - | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| EQB63_RS14715 () | 107951..109123 | + | 1173 | WP_000195429.1 | IS256 family transposase IS256 | Transposase |
| EQB63_RS14720 () | 109253..110692 | - | 1440 | WP_001028141.1 | Bifunctional AAC/APH | ARG |
| EQB63_RS14725 () | 110693..111085 | - | 393 | WP_025189010.1 | GNAT family N-acetyltransferase | - |
| EQB63_RS14730 () | 111069..111623 | - | 555 | Protein_112 | aminoglycoside phosphotransferase family protein | - |
| EQB63_RS14735 () | 111722..112894 | + | 1173 | WP_000195429.1 | IS256 family transposase IS256 | Transposase |
| EQB63_RS14740 () | 112947..113636 | - | 690 | Protein_114 | GNAT family N-acetyltransferase | - |
| EQB63_RS14745 () | 113691..113867 | - | 177 | Protein_115 | IS6 family transposase | - |
| EQB63_RS14750 () | 114027..115064 | - | 1038 | WP_002303110.1 | IS3 family transposase ISSde10 | Transposase |
| EQB63_RS14755 () | 115061..115573 | - | 513 | WP_002303111.1 | IS3 family transposase ISPa31 | Transposase |
| EQB63_RS14760 () | 115643..115897 | - | 255 | Protein_118 | replication initiation protein | - |
| EQB63_RS14765 () | 116573..117124 | - | 552 | WP_002303113.1 | DUF334 domain-containing protein | - |
| EQB63_RS14770 () | 117219..117599 | - | 381 | Protein_120 | IS6 family transposase IS1216V | Transposase |
| EQB63_RS14780 () | 117669..118349 | + | 681 | WP_002319817.1 | IS6 family transposase IS1297 | Transposase |
| EQB63_RS14785 () | 118609..119214 | + | 606 | WP_002321606.1 | Tn3 family transposase TnpR_ISPa40 | Transposase |
| EQB63_RS14790 () | 119259..119426 | - | 168 | WP_000824191.1 | hypothetical protein | - |
| EQB63_RS14795 () | 119460..119759 | - | 300 | WP_000366408.1 | BRCT domain-containing protein | - |
| EQB63_RS14800 () | 119800..120417 | - | 618 | WP_001224538.1 | Tn3 family transposase TnpR_TnAs2 | Transposase |
| EQB63_RS14805 () | 120732..122027 | + | 1296 | WP_002297218.1 | ISL3 family transposase ISEfa11 | Transposase |
| EQB63_RS14815 () | 122264..122659 | - | 396 | WP_002304891.1 | hypothetical protein | - |
| EQB63_RS14820 () | 122739..125090 | - | 2352 | WP_000344083.1 | DUF1906 domain-containing protein | - |
| EQB63_RS14825 () | 125215..125904 | - | 690 | WP_002346986.1 | hypothetical protein | - |
| EQB63_RS14830 () | 125918..126370 | - | 453 | WP_000751236.1 | hypothetical protein | - |
| EQB63_RS14835 () | 126501..127181 | + | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| EQB63_RS14840 () | 127283..128602 | - | 1320 | WP_002300494.1 | HAMP domain-containing histidine kinase | - |
| EQB63_RS14845 () | 128599..129252 | - | 654 | WP_002285815.1 | Transcriptional regulatory protein QseB | VF |
| EQB63_RS14855 () | 129540..130060 | + | 521 | Protein_134 | transposase | - |
| EQB63_RS14860 () | 129962..130678 | - | 717 | WP_002348630.1 | aminotransferase class V-fold PLP-dependent enzyme | - |
| EQB63_RS14865 () | 130728..130937 | - | 210 | WP_002302256.1 | hypothetical protein | - |
| EQB63_RS14870 () | 131214..132487 | + | 1274 | Protein_137 | ISL3 family transposase ISEfa11 | Transposase |
| EQB63_RS14875 () | 132594..133625 | - | 1032 | WP_002302261.1 | Spermidine/putrescine import ATP-binding protein PotA | VF |
| EQB63_RS14880 () | 133632..134462 | - | 831 | WP_002313180.1 | ABC transporter permease | - |
| EQB63_RS14885 () | 134459..135274 | - | 816 | WP_002330693.1 | ABC transporter permease subunit | - |
| EQB63_RS14890 () | 135271..136095 | - | 825 | WP_002302267.1 | alkaline phosphatase family protein | - |
| EQB63_RS14895 () | 136085..137185 | - | 1101 | WP_002302268.1 | extracellular solute-binding protein | - |
| EQB63_RS14900 () | 137363..138148 | + | 786 | WP_002302270.1 | histidinol phosphate phosphatase | - |
| EQB63_RS14905 () | 138181..138564 | + | 384 | WP_002330694.1 | hypothetical protein | - |
| EQB63_RS14910 () | 138640..138771 | + | 132 | WP_077828694.1 | peptidylprolyl isomerase | - |
| EQB63_RS14915 () | 138740..138976 | + | 237 | WP_002322470.1 | Putative bifunctional phosphatase/peptidyl-prolyl cis-trans isomerase | VF |
| EQB63_RS14925 () | 139054..140025 | - | 972 | WP_002302275.1 | radical SAM protein | - |
| EQB63_RS14930 () | 140677..142299 | + | 1623 | WP_049142603.1 | IS1182 family transposase ISEfa7 | Transposase |
| EQB63_RS14935 () | 142585..143961 | - | 1377 | WP_002301195.1 | ABC transporter permease | - |
| EQB63_RS14940 () | 143961..144617 | - | 657 | WP_002298083.1 | putative ABC transporter ATP-binding protein | VF |
| EQB63_RS14945 () | 144627..145790 | - | 1164 | WP_127836243.1 | ABC transporter permease | - |
| EQB63_RS14950 () | 145856..147034 | + | 1179 | WP_000997695.1 | IS256 family transposase ISEf1 | Transposase |
| EQB63_RS14955 () | 147086..147250 | - | 165 | Protein_153 | ABC transporter permease | - |
| EQB63_RS14960 () | 147269..147424 | - | 156 | Protein_154 | 4Fe-4S binding protein | - |
| EQB63_RS14965 () | 147500..148662 | + | 1163 | WP_087121905.1 | IS3 family transposase ISEfa8 | Transposase |
| EQB63_RS14970 () | 148692..149141 | - | 450 | WP_010729386.1 | TlpA family protein disulfide reductase | - |
| EQB63_RS16445 () | 149297..149839 | - | 543 | WP_002298088.1 | hypothetical protein | - |
| EQB63_RS14985 () | 150114..150757 | + | 644 | Protein_158 | transposase | - |
| EQB63_RS14990 () | 150833..151513 | + | 681 | WP_002331383.1 | IS6 family transposase IS1216E | Transposase |
| EQB63_RS14995 () | 151568..151924 | - | 357 | Protein_160 | hypothetical protein | - |
| EQB63_RS15000 () | 152184..152732 | - | 549 | WP_002292681.1 | hypothetical protein | - |
| EQB63_RS15005 () | 152733..153590 | - | 858 | WP_002292680.1 | AAA family ATPase | - |
| EQB63_RS15010 () | 153876..154162 | - | 287 | Protein_163 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| EQB63_RS15015 () | 154152..154481 | - | 330 | WP_002292678.1 | AbrB family transcriptional regulator | - |
| EQB63_RS15020 () | 154558..154830 | - | 273 | WP_002314366.1 | Txe/YoeB family addiction module toxin | Toxin Detail |
| EQB63_RS15025 () | 154830..155093 | - | 264 | WP_002297422.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| EQB63_RS15030 () | 155327..156235 | + | 909 | Protein_167 | IS982 family transposase ISEfm1 | Transposase |
| EQB63_RS15035 () | 156238..157413 | - | 1176 | WP_002336205.1 | MFS transporter | - |
| EQB63_RS15040 () | 157416..159665 | - | 2250 | WP_002314387.1 | alpha-galactosidase | - |
| EQB63_RS15045 () | 159762..160616 | - | 855 | WP_002338109.1 | AraC family transcriptional regulator | - |
| EQB63_RS15050 () | 160698..161606 | - | 909 | Protein_171 | IS982 family transposase ISEfm1 | Transposase |
| EQB63_RS15055 () | 161700..162635 | - | 936 | WP_002323400.1 | hypothetical protein | - |
| EQB63_RS15060 () | 163194..163511 | - | 318 | WP_002290394.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| EQB63_RS15065 () | 163512..163766 | - | 255 | WP_002323399.1 | hypothetical protein | - |
| EQB63_RS15070 () | 164125..164529 | + | 405 | WP_002287522.1 | IS200-IS605 family transposase ISEfa4 | Transposase |
| EQB63_RS15075 () | 164546..165694 | + | 1149 | WP_002287525.1 | IS200-IS605 family transposase ISEfa4 | Transposase |
| EQB63_RS15080 () | 165917..166135 | - | 219 | Protein_177 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| EQB63_RS15085 () | 166401..166595 | - | 195 | WP_002348857.1 | hypothetical protein | - |
| EQB63_RS15090 () | 166695..166781 | - | 87 | Protein_179 | single-stranded DNA-binding protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|