MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 165514 bp
Accession: NZ_LR135220 Location: 1..165514 Organism: Enterococcus faecium isolate E7040 Replicon: plasmid 2
Accession: NZ_LR135220 Location: 1..165514 Organism: Enterococcus faecium isolate E7040 Replicon: plasmid 2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EQB60_RS13870 () | 1..1041 | + | 1041 | WP_002326172.1 | replication initiator protein A | - |
| EQB60_RS13875 () | 1865..2197 | + | 333 | WP_002323647.1 | hypothetical protein | - |
| EQB60_RS13880 () | 2816..3157 | + | 342 | WP_002314399.1 | DUF5406 domain-containing protein | - |
| EQB60_RS13885 () | 3394..4644 | - | 1251 | WP_002297404.1 | IS110 family transposase ISSpn10 | Transposase |
| EQB60_RS13890 () | 5054..7426 | + | 2373 | WP_126341262.1 | hypothetical protein | - |
| EQB60_RS13895 () | 7487..8947 | + | 1461 | WP_127822559.1 | toprim domain-containing protein | - |
| EQB60_RS13900 () | 8958..11163 | + | 2206 | Protein_6 | DNA topoisomerase III | - |
| EQB60_RS16370 () | 11179..11328 | + | 150 | WP_002326517.1 | hypothetical protein | - |
| EQB60_RS13905 () | 11403..11996 | + | 594 | WP_002296244.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | - |
| EQB60_RS13910 () | 12009..12908 | + | 900 | WP_010733696.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
| EQB60_RS13915 () | 12911..13408 | + | 498 | WP_002326885.1 | single-stranded DNA-binding protein | - |
| EQB60_RS13920 () | 13774..14034 | + | 261 | WP_002296240.1 | hypothetical protein | - |
| EQB60_RS13925 () | 14479..14685 | + | 207 | WP_002325537.1 | hypothetical protein | - |
| EQB60_RS13930 () | 14733..14936 | + | 204 | WP_110300627.1 | hypothetical protein | - |
| EQB60_RS13935 () | 14952..15389 | + | 438 | WP_126341263.1 | hypothetical protein | - |
| EQB60_RS13940 () | 15382..16089 | + | 708 | WP_002332739.1 | hypothetical protein | - |
| EQB60_RS13950 () | 16469..16699 | + | 231 | WP_126341264.1 | hypothetical protein | - |
| EQB60_RS13955 () | 16925..17188 | + | 264 | WP_002287514.1 | hypothetical protein | Antitoxin Detail |
| EQB60_RS13960 () | 17182..17532 | + | 351 | WP_002321032.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin Detail |
| EQB60_RS13965 () | 17556..18170 | - | 615 | WP_002318230.1 | Tn3 family transposase TnpR_TnAs2 | Transposase |
| EQB60_RS13970 () | 18484..18906 | + | 423 | WP_002288787.1 | hypothetical protein | - |
| EQB60_RS13975 () | 18916..19119 | + | 204 | WP_002299573.1 | hypothetical protein | - |
| EQB60_RS13980 () | 19330..19920 | + | 591 | WP_065305702.1 | Tn3 family transposase TnBth3 | Transposase |
| EQB60_RS13985 () | 20073..20687 | + | 615 | WP_065305703.1 | Tn3 family transposase TnpR_ISPa40 | Transposase |
| EQB60_RS13990 () | 20711..21880 | + | 1170 | Protein_24 | hypothetical protein | - |
| EQB60_RS13995 () | 21872..22831 | - | 960 | WP_002297271.1 | IS30 family transposase IS6770 | Transposase |
| EQB60_RS14000 () | 23590..23927 | + | 338 | Protein_26 | recombinase family protein | - |
| EQB60_RS14005 () | 23927..25050 | + | 1124 | Protein_27 | DNA topoisomerase | - |
| EQB60_RS14015 () | 25337..25576 | - | 240 | Protein_28 | HAD family hydrolase | - |
| EQB60_RS14020 () | 25637..26799 | + | 1163 | WP_086956687.1 | IS3 family transposase IS1485 | Transposase |
| EQB60_RS14025 () | 26905..27552 | - | 648 | WP_106018936.1 | HAD family hydrolase | - |
| EQB60_RS14030 () | 27557..28324 | - | 768 | WP_002345826.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| EQB60_RS14035 () | 28813..29238 | + | 426 | WP_002290555.1 | galactose-6-phosphate isomerase subunit LacA | - |
| EQB60_RS14040 () | 29255..29770 | + | 516 | WP_070828487.1 | galactose-6-phosphate isomerase subunit LacB | - |
| EQB60_RS14045 () | 29781..30713 | + | 933 | WP_070828488.1 | tagatose-6-phosphate kinase | - |
| EQB60_RS14050 () | 30716..31696 | + | 981 | WP_002290551.1 | tagatose-bisphosphate aldolase | - |
| EQB60_RS14055 () | 31724..32041 | + | 318 | WP_002290550.1 | PTS lactose/cellobiose transporter subunit IIA | - |
| EQB60_RS14060 () | 32041..33747 | + | 1707 | WP_070828490.1 | lactose-specific PTS transporter subunit EIIC | - |
| EQB60_RS14065 () | 33894..35300 | + | 1407 | WP_002290548.1 | 6-phospho-beta-galactosidase | - |
| EQB60_RS16375 () | 35423..35596 | + | 174 | WP_164855624.1 | DUF3884 family protein | - |
| EQB60_RS14075 () | 35617..36516 | + | 900 | WP_002345823.1 | aldose 1-epimerase family protein | - |
| EQB60_RS14080 () | 36922..37326 | + | 405 | WP_002287522.1 | IS200-IS605 family transposase ISEfa4 | Transposase |
| EQB60_RS14085 () | 37343..38491 | + | 1149 | WP_002287525.1 | IS200-IS605 family transposase ISEfa4 | Transposase |
| EQB60_RS14090 () | 38825..40438 | + | 1614 | WP_126341265.1 | ATP-binding protein | - |
| EQB60_RS14095 () | 40441..41130 | + | 690 | WP_126341266.1 | RloB family protein | - |
| EQB60_RS14100 () | 41119..42414 | - | 1296 | WP_127822560.1 | ISL3 family transposase IS1251 | Transposase |
| EQB60_RS14105 () | 42946..43500 | + | 555 | WP_002301108.1 | tyrosine-type recombinase/integrase | - |
| EQB60_RS16380 () | 43754..44334 | + | 581 | Protein_47 | hypothetical protein | - |
| EQB60_RS14115 () | 44377..44583 | + | 207 | WP_077974490.1 | hypothetical protein | - |
| EQB60_RS14120 () | 44805..45662 | - | 858 | WP_197724757.1 | IS982 family transposase ISEfm1 | Transposase |
| EQB60_RS14125 () | 45909..47099 | + | 1191 | Protein_50 | IS256 family transposase ISLgar5 | Transposase |
| EQB60_RS14130 () | 47518..48717 | + | 1200 | WP_073466303.1 | MFS transporter | - |
| EQB60_RS14135 () | 49252..50414 | + | 1163 | WP_086956687.1 | IS3 family transposase IS1485 | Transposase |
| EQB60_RS14140 () | 50581..51339 | - | 759 | WP_073466287.1 | MurR/RpiR family transcriptional regulator | - |
| EQB60_RS14145 () | 51523..52431 | + | 909 | WP_077974480.1 | IS982 family transposase ISEfm1 | Transposase |
| EQB60_RS14150 () | 52556..53491 | + | 936 | WP_073466326.1 | 1-phosphofructokinase | - |
| EQB60_RS14155 () | 53488..54933 | + | 1446 | WP_073466327.1 | PTS fructose transporter subunit IIBC | - |
| EQB60_RS14160 () | 54961..55416 | + | 456 | WP_002336650.1 | fructose PTS transporter subunit IIA | - |
| EQB60_RS14165 () | 55435..56409 | + | 975 | WP_005880910.1 | tagatose-bisphosphate aldolase | - |
| EQB60_RS14170 () | 56519..57004 | - | 486 | Protein_59 | TetR family transcriptional regulator C-terminal domain-containing protein | - |
| EQB60_RS14175 () | 57164..57847 | - | 684 | WP_164855625.1 | IS6 family transposase IS1216E | Transposase |
| EQB60_RS14180 () | 57918..58184 | + | 267 | Protein_61 | LacI family DNA-binding transcriptional regulator | - |
| EQB60_RS14185 () | 58429..59454 | + | 1026 | WP_002290378.1 | LacI family DNA-binding transcriptional regulator | - |
| EQB60_RS14190 () | 59748..60857 | + | 1110 | WP_002335321.1 | sugar ABC transporter substrate-binding protein | - |
| EQB60_RS14195 () | 60940..61836 | + | 897 | Protein_64 | sugar ABC transporter permease | - |
| EQB60_RS14200 () | 61852..62676 | + | 825 | WP_047929206.1 | carbohydrate ABC transporter permease | - |
| EQB60_RS14205 () | 62708..64018 | + | 1311 | WP_002341308.1 | alpha-glucosidase/alpha-galactosidase | - |
| EQB60_RS16385 () | 64166..64315 | + | 150 | WP_010728938.1 | hypothetical protein | - |
| EQB60_RS16390 () | 64329..64478 | + | 150 | WP_010728938.1 | hypothetical protein | - |
| EQB60_RS14210 () | 64492..65751 | + | 1260 | WP_002290371.1 | extracellular solute-binding protein | - |
| EQB60_RS14215 () | 65761..66633 | + | 873 | WP_002290370.1 | sugar ABC transporter permease | - |
| EQB60_RS14220 () | 66645..67475 | + | 831 | WP_002290368.1 | carbohydrate ABC transporter permease | - |
| EQB60_RS14225 () | 67515..69698 | + | 2184 | WP_002324534.1 | alpha-galactosidase | - |
| EQB60_RS14230 () | 69759..70979 | + | 1221 | WP_073466380.1 | oligo-1,6-glucosidase | - |
| EQB60_RS14235 () | 70976..72436 | + | 1461 | WP_002324531.1 | sucrose phosphorylase | - |
| EQB60_RS14240 () | 72513..73619 | + | 1107 | Protein_75 | IS4 family transposase IS641 | Transposase |
| EQB60_RS14245 () | 73941..74150 | + | 210 | WP_002290357.1 | DUF3173 domain-containing protein | - |
| EQB60_RS14250 () | 74143..74292 | + | 150 | WP_002290356.1 | hypothetical protein | - |
| EQB60_RS14255 () | 74446..75111 | + | 666 | WP_002324528.1 | site-specific integrase | - |
| EQB60_RS14260 () | 75395..76480 | - | 1086 | WP_002290352.1 | tyrosine recombinase XerS | - |
| EQB60_RS14265 () | 76814..77047 | + | 234 | WP_002290351.1 | addiction module antitoxin | - |
| EQB60_RS14270 () | 77044..77451 | + | 408 | WP_002329899.1 | type II toxin-antitoxin system death-on-curing family toxin | - |
| EQB60_RS14280 () | 78588..79106 | - | 519 | WP_002287870.1 | ClbS/DfsB family four-helix bundle protein | - |
| EQB60_RS14295 () | 80285..81447 | + | 1163 | WP_127822562.1 | IS3 family transposase IS1485 | Transposase |
| EQB60_RS14300 () | 81738..81848 | + | 111 | Protein_84 | transposase | - |
| EQB60_RS14305 () | 81945..82421 | - | 477 | WP_065305738.1 | PTS glucose transporter subunit IIA | - |
| EQB60_RS14310 () | 82434..83936 | - | 1503 | WP_002289252.1 | PTS transporter subunit EIIC | - |
| EQB60_RS14315 () | 83950..84639 | - | 690 | WP_002289253.1 | N-acetylmannosamine-6-phosphate 2-epimerase | - |
| EQB60_RS14320 () | 84800..85618 | + | 819 | WP_002289254.1 | MurR/RpiR family transcriptional regulator | - |
| EQB60_RS14325 () | 85962..86138 | - | 177 | Protein_89 | foldase PrsA domain protein | - |
| EQB60_RS14330 () | 86693..87871 | + | 1179 | WP_065305739.1 | IS256 family transposase ISEfm2 | Transposase |
| EQB60_RS16460 () | 88582..89381 | + | 800 | Protein_91 | ISL3 family transposase | - |
| EQB60_RS14350 () | 89718..90968 | - | 1251 | WP_002330944.1 | PTS sugar transporter subunit IIC | - |
| EQB60_RS14355 () | 90987..91913 | - | 927 | WP_002298736.1 | PEP phosphonomutase | - |
| EQB60_RS14360 () | 91992..92987 | - | 996 | WP_002301128.1 | tagatose-bisphosphate aldolase | - |
| EQB60_RS14365 () | 93003..94172 | - | 1170 | WP_002301130.1 | SIS domain-containing protein | - |
| EQB60_RS14370 () | 94188..94922 | - | 735 | WP_002301131.1 | GntR family transcriptional regulator | - |
| EQB60_RS14380 () | 97114..98453 | + | 1340 | WP_086953915.1 | IS3 family transposase ISEnfa3 | Transposase |
| EQB60_RS14385 () | 98843..100135 | - | 1293 | WP_002301811.1 | IS256 family transposase ISBsu2 | Transposase |
| EQB60_RS14390 () | 100409..100669 | - | 261 | WP_002313174.1 | hypothetical protein | - |
| EQB60_RS14395 () | 100920..102098 | + | 1179 | WP_002346943.1 | IS256 family transposase ISEf1 | Transposase |
| EQB60_RS14400 () | 102450..102746 | + | 297 | WP_073120200.1 | IS3 family transposase ISEfa8 | Transposase |
| EQB60_RS14405 () | 102669..103493 | - | 825 | Protein_103 | IS3 family transposase ISEfa8 | Transposase |
| EQB60_RS14410 () | 103695..104090 | - | 396 | WP_002287876.1 | aspartate 1-decarboxylase | - |
| EQB60_RS14415 () | 104100..104948 | - | 849 | WP_002287875.1 | pantoate--beta-alanine ligase | - |
| EQB60_RS14420 () | 104963..105790 | - | 828 | WP_002287874.1 | 3-methyl-2-oxobutanoate hydroxymethyltransferase | - |
| EQB60_RS14425 () | 105802..106662 | - | 861 | WP_002349114.1 | Rossmann-like and DUF2520 domain-containing protein | - |
| EQB60_RS14430 () | 106900..108069 | + | 1170 | WP_002300493.1 | IS256 family transposase ISEfa13 | Transposase |
| EQB60_RS14435 () | 108409..109089 | - | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| EQB60_RS14440 () | 109719..110891 | + | 1173 | WP_000195429.1 | IS256 family transposase IS256 | Transposase |
| EQB60_RS14445 () | 111021..112460 | - | 1440 | WP_001028141.1 | Bifunctional AAC/APH | ARG |
| EQB60_RS14450 () | 112461..112853 | - | 393 | WP_025189010.1 | GNAT family N-acetyltransferase | - |
| EQB60_RS14455 () | 112837..114072 | - | 1236 | Protein_113 | Bifunctional AAC/APH | ARG |
| EQB60_RS14460 () | 114127..114303 | - | 177 | Protein_114 | IS6 family transposase | - |
| EQB60_RS14465 () | 114463..115500 | - | 1038 | WP_002303110.1 | IS3 family transposase ISSde10 | Transposase |
| EQB60_RS14470 () | 115497..116009 | - | 513 | WP_002303111.1 | IS3 family transposase ISPa31 | Transposase |
| EQB60_RS14475 () | 116079..116333 | - | 255 | Protein_117 | replication initiation protein | - |
| EQB60_RS14480 () | 117009..117560 | - | 552 | WP_002303113.1 | DUF334 domain-containing protein | - |
| EQB60_RS14485 () | 117655..118035 | - | 381 | Protein_119 | IS6 family transposase IS1216V | Transposase |
| EQB60_RS14495 () | 118105..118785 | + | 681 | WP_002319817.1 | IS6 family transposase IS1297 | Transposase |
| EQB60_RS14500 () | 119045..119650 | + | 606 | WP_002321606.1 | Tn3 family transposase TnpR_ISPa40 | Transposase |
| EQB60_RS14505 () | 119695..119862 | - | 168 | WP_000824191.1 | hypothetical protein | - |
| EQB60_RS14510 () | 119896..120195 | - | 300 | WP_000366408.1 | BRCT domain-containing protein | - |
| EQB60_RS14515 () | 120236..120853 | - | 618 | WP_001224538.1 | Tn3 family transposase TnpR_TnAs2 | Transposase |
| EQB60_RS14520 () | 121178..121573 | - | 396 | WP_002304891.1 | hypothetical protein | - |
| EQB60_RS14525 () | 121653..124004 | - | 2352 | WP_000344083.1 | DUF1906 domain-containing protein | - |
| EQB60_RS14530 () | 124129..124818 | - | 690 | WP_002346986.1 | hypothetical protein | - |
| EQB60_RS14535 () | 124832..125284 | - | 453 | WP_000751236.1 | hypothetical protein | - |
| EQB60_RS14540 () | 125415..126095 | + | 681 | WP_001015311.1 | IS6 family transposase IS1216E | Transposase |
| EQB60_RS14545 () | 126197..127516 | - | 1320 | WP_002300494.1 | HAMP domain-containing histidine kinase | - |
| EQB60_RS14550 () | 127513..128166 | - | 654 | WP_002285815.1 | Transcriptional regulatory protein QseB | VF |
| EQB60_RS14560 () | 128454..128974 | + | 521 | Protein_132 | transposase | - |
| EQB60_RS14565 () | 128876..129592 | - | 717 | WP_002348630.1 | aminotransferase class V-fold PLP-dependent enzyme | - |
| EQB60_RS16395 () | 129716..129901 | - | 186 | WP_016922460.1 | hypothetical protein | - |
| EQB60_RS14575 () | 130128..131401 | + | 1274 | Protein_135 | ISL3 family transposase ISEfa11 | Transposase |
| EQB60_RS14580 () | 131508..132539 | - | 1032 | WP_002302261.1 | Vitamin B12 import ATP-binding protein BtuD | VF |
| EQB60_RS14585 () | 132546..133376 | - | 831 | WP_002313180.1 | ABC transporter permease | - |
| EQB60_RS14590 () | 133373..134188 | - | 816 | WP_002330693.1 | ABC transporter permease subunit | - |
| EQB60_RS14595 () | 134185..135009 | - | 825 | WP_002302267.1 | alkaline phosphatase family protein | - |
| EQB60_RS14600 () | 134999..136099 | - | 1101 | WP_002302268.1 | extracellular solute-binding protein | - |
| EQB60_RS14605 () | 136277..137062 | + | 786 | WP_002302270.1 | histidinol phosphate phosphatase | - |
| EQB60_RS14610 () | 137095..137478 | + | 384 | WP_002330694.1 | hypothetical protein | - |
| EQB60_RS14615 () | 137554..137685 | + | 132 | WP_077828694.1 | peptidylprolyl isomerase | - |
| EQB60_RS14620 () | 137654..137890 | + | 237 | WP_002322470.1 | Putative bifunctional phosphatase/peptidyl-prolyl cis-trans isomerase | VF |
| EQB60_RS14630 () | 137968..138939 | - | 972 | WP_002302275.1 | radical SAM protein | - |
| EQB60_RS14635 () | 139591..141213 | + | 1623 | WP_049142603.1 | IS1182 family transposase ISEfa7 | Transposase |
| EQB60_RS14640 () | 141499..142875 | - | 1377 | WP_002301195.1 | ABC transporter permease | - |
| EQB60_RS14645 () | 142875..143531 | - | 657 | WP_002298083.1 | putative ABC transporter ATP-binding protein | VF |
| EQB60_RS14650 () | 143541..144818 | - | 1278 | WP_002301194.1 | ABC transporter permease | - |
| EQB60_RS14655 () | 144837..144992 | - | 156 | Protein_150 | 4Fe-4S binding protein | - |
| EQB60_RS14660 () | 145068..146230 | + | 1163 | WP_087121905.1 | IS3 family transposase ISEfa8 | Transposase |
| EQB60_RS14665 () | 146260..146709 | - | 450 | WP_010729386.1 | TlpA family protein disulfide reductase | - |
| EQB60_RS16400 () | 146865..147407 | - | 543 | WP_002298088.1 | hypothetical protein | - |
| EQB60_RS14680 () | 147682..148325 | + | 644 | Protein_154 | transposase | - |
| EQB60_RS14685 () | 148401..149081 | + | 681 | WP_002331383.1 | IS6 family transposase IS1216E | Transposase |
| EQB60_RS14690 () | 149136..149492 | - | 357 | Protein_156 | hypothetical protein | - |
| EQB60_RS14695 () | 149752..150300 | - | 549 | WP_002292681.1 | hypothetical protein | - |
| EQB60_RS14700 () | 150301..151158 | - | 858 | WP_002292680.1 | AAA family ATPase | - |
| EQB60_RS14705 () | 151444..151730 | - | 287 | Protein_159 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| EQB60_RS14710 () | 151720..152049 | - | 330 | WP_002292678.1 | AbrB family transcriptional regulator | - |
| EQB60_RS14715 () | 152126..152398 | - | 273 | WP_002314366.1 | Txe/YoeB family addiction module toxin | Toxin Detail |
| EQB60_RS14720 () | 152398..152661 | - | 264 | WP_002297422.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| EQB60_RS14725 () | 152895..153803 | + | 909 | Protein_163 | IS982 family transposase ISEfm1 | Transposase |
| EQB60_RS14730 () | 153806..154981 | - | 1176 | WP_002336205.1 | MFS transporter | - |
| EQB60_RS14735 () | 154984..157233 | - | 2250 | WP_002314387.1 | alpha-galactosidase | - |
| EQB60_RS14740 () | 157330..158184 | - | 855 | WP_002338109.1 | AraC family transcriptional regulator | - |
| EQB60_RS14745 () | 158266..159174 | - | 909 | Protein_167 | IS982 family transposase ISEfm1 | Transposase |
| EQB60_RS14750 () | 159268..160203 | - | 936 | WP_002323400.1 | hypothetical protein | - |
| EQB60_RS14755 () | 160762..161079 | - | 318 | WP_002290394.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| EQB60_RS14760 () | 161080..161334 | - | 255 | WP_002323399.1 | hypothetical protein | - |
| EQB60_RS14765 () | 161693..162097 | + | 405 | WP_002287522.1 | IS200-IS605 family transposase ISEfa4 | Transposase |
| EQB60_RS14770 () | 162114..163262 | + | 1149 | WP_002287525.1 | IS200-IS605 family transposase ISEfa4 | Transposase |
| EQB60_RS14775 () | 163485..163703 | - | 219 | Protein_173 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| EQB60_RS14780 () | 163969..164163 | - | 195 | WP_002348857.1 | hypothetical protein | - |
| EQB60_RS14785 () | 164263..164349 | - | 87 | Protein_175 | single-stranded DNA-binding protein | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|