Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yefM-yoeB (relBE)/Txe-RelB |
Location | 152126..152661 | Replicon | plasmid 2 |
Accession | NZ_LR135220 | ||
Organism | Enterococcus faecium isolate E7040 |
Toxin (Protein)
Gene name | yoeB | Uniprot ID | R2PQC0 |
Locus tag | EQB60_RS14715 | Protein ID | WP_002314366.1 |
Coordinates | 152126..152398 (-) | Length | 91 a.a. |
Antitoxin (Protein)
Gene name | yefM | Uniprot ID | Q3Y220 |
Locus tag | EQB60_RS14720 | Protein ID | WP_002297422.1 |
Coordinates | 152398..152661 (-) | Length | 88 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
EQB60_RS14680 | 147682..148325 | + | 644 | Protein_154 | transposase | - |
EQB60_RS14685 | 148401..149081 | + | 681 | WP_002331383.1 | IS6-like element IS1216 family transposase | - |
EQB60_RS14690 | 149136..149492 | - | 357 | Protein_156 | hypothetical protein | - |
EQB60_RS14695 | 149752..150300 | - | 549 | WP_002292681.1 | hypothetical protein | - |
EQB60_RS14700 | 150301..151158 | - | 858 | WP_002292680.1 | AAA family ATPase | - |
EQB60_RS14705 | 151444..151730 | - | 287 | Protein_159 | type II toxin-antitoxin system RelE/ParE family toxin | - |
EQB60_RS14710 | 151720..152049 | - | 330 | WP_002292678.1 | AbrB family transcriptional regulator | - |
EQB60_RS14715 | 152126..152398 | - | 273 | WP_002314366.1 | Txe/YoeB family addiction module toxin | Toxin |
EQB60_RS14720 | 152398..152661 | - | 264 | WP_002297422.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
EQB60_RS14725 | 152895..153803 | + | 909 | Protein_163 | IS982 family transposase | - |
EQB60_RS14730 | 153806..154981 | - | 1176 | WP_002336205.1 | MFS transporter | - |
EQB60_RS14735 | 154984..157233 | - | 2250 | WP_002314387.1 | alpha-galactosidase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | aac(6')-aph(2'') / aph(2'')-Ia | - | 1..165514 | 165514 | |
- | inside | IScluster/Tn | - | - | 139591..163262 | 23671 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A829F704 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A829F006 |