MGE detailed information
MGE type: Non-Mobilizable plasmid MGE length: 145361 bp
Accession: NZ_LR135192 Location: 1..145361 Organism: Enterococcus faecium isolate E4438 Replicon: plasmid 2
Accession: NZ_LR135192 Location: 1..145361 Organism: Enterococcus faecium isolate E4438 Replicon: plasmid 2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EL354_RS14040 () | 1..1041 | + | 1041 | WP_002303636.1 | replication initiator protein A | - |
| EL354_RS14045 () | 1865..2197 | + | 333 | WP_002323647.1 | hypothetical protein | - |
| EL354_RS14050 () | 2816..3157 | + | 342 | WP_002295674.1 | DUF5406 domain-containing protein | - |
| EL354_RS14055 () | 3271..3510 | + | 240 | WP_002295673.1 | hypothetical protein | - |
| EL354_RS14060 () | 3577..3813 | + | 237 | WP_002323648.1 | hypothetical protein | - |
| EL354_RS14065 () | 3877..4836 | + | 960 | WP_002303350.1 | IS30 family transposase IS1062 | Transposase |
| EL354_RS14070 () | 4912..5583 | + | 672 | WP_002295671.1 | class A sortase | - |
| EL354_RS14075 () | 5636..7612 | + | 1977 | WP_002323239.1 | isopeptide-forming domain-containing fimbrial protein | - |
| EL354_RS14080 () | 7627..8379 | + | 753 | WP_002293487.1 | Sortase A | VF |
| EL354_RS14085 () | 8395..9156 | + | 762 | WP_002295669.1 | hypothetical protein | - |
| EL354_RS14090 () | 9169..9429 | + | 261 | WP_002293489.1 | hypothetical protein | - |
| EL354_RS14095 () | 9426..11516 | + | 2091 | WP_002326170.1 | isopeptide-forming domain-containing fimbrial protein | - |
| EL354_RS14100 () | 11543..12007 | + | 465 | WP_025477618.1 | hypothetical protein | - |
| EL354_RS14105 () | 12004..12246 | + | 243 | WP_002305229.1 | DUF5415 family protein | - |
| EL354_RS14110 () | 12264..12566 | + | 303 | WP_002295662.1 | hypothetical protein | - |
| EL354_RS14115 () | 12636..14690 | + | 2055 | WP_002323241.1 | hypothetical protein | - |
| EL354_RS14120 () | 14690..16519 | + | 1830 | WP_126309522.1 | type IV secretory system conjugative DNA transfer family protein | - |
| EL354_RS14125 () | 17232..19130 | + | 1899 | WP_002332870.1 | group II intron reverse transcriptase/maturase | - |
| EL354_RS14130 () | 19247..20050 | + | 804 | Protein_18 | TraM recognition domain-containing protein | - |
| EL354_RS14135 () | 20047..22443 | + | 2397 | WP_002323242.1 | hypothetical protein | - |
| EL354_RS14140 () | 22495..22827 | + | 333 | WP_002295656.1 | hypothetical protein | - |
| EL354_RS14145 () | 22828..23421 | + | 594 | WP_002340492.1 | hypothetical protein | - |
| EL354_RS14150 () | 23584..25608 | + | 2025 | WP_002307536.1 | ATPase | - |
| EL354_RS14155 () | 25608..26813 | + | 1206 | WP_005877003.1 | glucosaminidase domain-containing protein | - |
| EL354_RS14160 () | 26829..27473 | + | 645 | WP_002321287.1 | hypothetical protein | - |
| EL354_RS14165 () | 27484..28290 | + | 807 | WP_002335356.1 | hypothetical protein | - |
| EL354_RS14170 () | 28313..28543 | + | 231 | WP_002316063.1 | hypothetical protein | - |
| EL354_RS14175 () | 28563..29624 | + | 1062 | WP_002335355.1 | hypothetical protein | - |
| EL354_RS14180 () | 29668..29937 | + | 270 | WP_002335354.1 | hypothetical protein | - |
| EL354_RS14185 () | 30170..30466 | + | 297 | WP_002299246.1 | hypothetical protein | - |
| EL354_RS14190 () | 30468..30890 | + | 423 | WP_002310988.1 | hypothetical protein | - |
| EL354_RS14195 () | 30910..32502 | + | 1593 | WP_002335353.1 | hypothetical protein | Relaxase |
| EL354_RS14200 () | 32514..32849 | + | 336 | WP_002295640.1 | hypothetical protein | - |
| EL354_RS14205 () | 32989..33183 | + | 195 | WP_002295639.1 | hypothetical protein | - |
| EL354_RS14210 () | 33196..35568 | + | 2373 | WP_126309524.1 | hypothetical protein | - |
| EL354_RS14215 () | 35629..37089 | + | 1461 | WP_002326158.1 | toprim domain-containing protein | - |
| EL354_RS14220 () | 37111..39303 | + | 2193 | WP_126309526.1 | type IA DNA topoisomerase | - |
| EL354_RS15380 () | 39319..39468 | + | 150 | WP_002295632.1 | hypothetical protein | - |
| EL354_RS14225 () | 39549..40145 | + | 597 | WP_002322762.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | - |
| EL354_RS14230 () | 40158..41057 | + | 900 | WP_002322763.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
| EL354_RS14235 () | 41060..41545 | + | 486 | WP_126309528.1 | single-stranded DNA-binding protein | - |
| EL354_RS14240 () | 41567..41824 | + | 258 | WP_002322647.1 | hypothetical protein | - |
| EL354_RS14245 () | 41983..42105 | - | 123 | WP_002295624.1 | putative holin-like toxin | - |
| EL354_RS14250 () | 42259..42519 | + | 261 | WP_002324498.1 | hypothetical protein | - |
| EL354_RS14255 () | 42609..43904 | - | 1296 | WP_002297218.1 | ISL3 family transposase ISEfa11 | Transposase |
| EL354_RS14260 () | 44489..44695 | + | 207 | WP_002324499.1 | hypothetical protein | - |
| EL354_RS14265 () | 44695..44946 | + | 252 | WP_002287517.1 | hypothetical protein | - |
| EL354_RS14270 () | 44962..45399 | + | 438 | WP_002305049.1 | hypothetical protein | - |
| EL354_RS14275 () | 45392..46099 | + | 708 | WP_002322978.1 | hypothetical protein | - |
| EL354_RS14285 () | 46721..46905 | + | 185 | Protein_49 | type II toxin-antitoxin system HicA family toxin | - |
| EL354_RS14290 () | 46939..47370 | + | 432 | WP_002326154.1 | type II toxin-antitoxin system HicB family antitoxin | - |
| EL354_RS14295 () | 47896..49044 | - | 1149 | WP_002287525.1 | IS200-IS605 family transposase ISEfa4 | Transposase |
| EL354_RS14300 () | 49061..49465 | - | 405 | WP_002287522.1 | IS200-IS605 family transposase ISEfa4 | Transposase |
| EL354_RS14305 () | 49669..50286 | + | 618 | WP_002323453.1 | Tn3 family transposase TnpR_TnAs1 | Transposase |
| EL354_RS14310 () | 50663..51841 | - | 1179 | WP_000997695.1 | IS256 family transposase ISEf1 | Transposase |
| EL354_RS14315 () | 52066..52350 | - | 285 | WP_085802738.1 | IS91 family transposase ISCARN110 | Transposase |
| EL354_RS14320 () | 52422..53375 | - | 954 | WP_002287760.1 | IS30 family transposase IS1252 | Transposase |
| EL354_RS14325 () | 53472..54230 | - | 759 | Protein_57 | IS982 family transposase ISEfm1 | Transposase |
| EL354_RS14330 () | 54341..54556 | + | 216 | Protein_58 | IS110 family transposase | - |
| EL354_RS14335 () | 54682..55653 | + | 972 | WP_002347423.1 | LacI family DNA-binding transcriptional regulator | - |
| EL354_RS14340 () | 55795..57108 | + | 1314 | WP_164856670.1 | sugar ABC transporter substrate-binding protein | - |
| EL354_RS14345 () | 57151..58017 | + | 867 | WP_002371809.1 | sugar ABC transporter permease | - |
| EL354_RS14350 () | 58014..58862 | + | 849 | WP_002347420.1 | carbohydrate ABC transporter permease | - |
| EL354_RS14355 () | 58876..60348 | + | 1473 | WP_002347419.1 | glycoside hydrolase family 32 protein | - |
| EL354_RS14360 () | 60365..61237 | + | 873 | WP_002347418.1 | ROK family protein | - |
| EL354_RS14365 () | 61471..61856 | - | 386 | Protein_65 | IS3 family transposase | - |
| EL354_RS14370 () | 61898..62937 | - | 1040 | Protein_66 | IS630 family transposase ISBs2 | Transposase |
| EL354_RS14375 () | 63015..64003 | + | 989 | Protein_67 | IS3 family transposase ISKpn38 | Transposase |
| EL354_RS14380 () | 64237..65109 | - | 873 | WP_002347415.1 | ROK family protein | - |
| EL354_RS14385 () | 65373..67319 | - | 1947 | WP_002324510.1 | sucrose-specific PTS transporter subunit IIBC | - |
| EL354_RS14390 () | 67504..68943 | + | 1440 | WP_002302078.1 | sucrose-6-phosphate hydrolase | - |
| EL354_RS14395 () | 68945..69907 | + | 963 | WP_002302077.1 | LacI family DNA-binding transcriptional regulator | - |
| EL354_RS14405 () | 71746..72201 | + | 456 | WP_002301718.1 | IS200-IS605 family transposase ISAac3 | Transposase |
| EL354_RS14415 () | 72466..72564 | + | 99 | Protein_74 | IS30 family transposase | - |
| EL354_RS14425 () | 73247..74065 | - | 819 | WP_002289254.1 | MurR/RpiR family transcriptional regulator | - |
| EL354_RS14430 () | 74226..74915 | + | 690 | WP_002289253.1 | N-acetylmannosamine-6-phosphate 2-epimerase | - |
| EL354_RS14435 () | 74929..76431 | + | 1503 | WP_002289252.1 | PTS transporter subunit EIIC | - |
| EL354_RS14440 () | 76444..76920 | + | 477 | WP_002300328.1 | PTS glucose transporter subunit IIA | - |
| EL354_RS14460 () | 79698..80216 | + | 519 | WP_002287870.1 | ClbS/DfsB family four-helix bundle protein | - |
| EL354_RS14470 () | 81353..81760 | - | 408 | WP_002297442.1 | type II toxin-antitoxin system death-on-curing family toxin | - |
| EL354_RS14475 () | 81757..81990 | - | 234 | WP_002297441.1 | addiction module antitoxin | - |
| EL354_RS14480 () | 82323..83408 | + | 1086 | WP_002297440.1 | tyrosine recombinase XerS | - |
| EL354_RS14485 () | 83694..84877 | + | 1184 | Protein_84 | IS256-like element ISEf1 family transposase | - |
| EL354_RS14490 () | 85112..85315 | + | 204 | Protein_85 | hypothetical protein | - |
| EL354_RS14495 () | 85368..86544 | - | 1177 | Protein_86 | IS256 family transposase ISEf1 | Transposase |
| EL354_RS14500 () | 86651..87346 | + | 696 | Protein_87 | hypothetical protein | - |
| EL354_RS14505 () | 87783..88337 | - | 555 | WP_002295761.1 | tyrosine-type recombinase/integrase | - |
| EL354_RS14510 () | 89080..89640 | + | 561 | WP_002347210.1 | hypothetical protein | - |
| EL354_RS14515 () | 89673..90485 | - | 813 | WP_002322679.1 | AAA family ATPase | - |
| EL354_RS14520 () | 90478..91914 | - | 1437 | WP_002322678.1 | DDE-type integrase/transposase/recombinase | - |
| EL354_RS14525 () | 91886..92479 | - | 594 | WP_002322677.1 | Tn3 family transposase TnBth3 | Transposase |
| EL354_RS14530 () | 92711..92941 | + | 231 | WP_002322676.1 | hypothetical protein | Antitoxin Detail |
| EL354_RS14535 () | 92941..93282 | + | 342 | WP_002322675.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin Detail |
| EL354_RS14540 () | 93496..94998 | - | 1503 | WP_002322674.1 | xylulokinase | - |
| EL354_RS14545 () | 95071..96123 | - | 1053 | WP_002323515.1 | sugar ABC transporter substrate-binding protein | - |
| EL354_RS14550 () | 96176..97144 | - | 969 | WP_002322672.1 | ABC transporter permease | - |
| EL354_RS14555 () | 97209..98717 | - | 1509 | WP_002322671.1 | sugar ABC transporter ATP-binding protein | - |
| EL354_RS14560 () | 98767..100377 | - | 1611 | WP_002322670.1 | glycoside hydrolase family 43 protein | - |
| EL354_RS14565 () | 100477..101784 | - | 1308 | WP_002322669.1 | xylose isomerase | - |
| EL354_RS14570 () | 102071..103225 | + | 1155 | WP_002323041.1 | ROK family transcriptional regulator | - |
| EL354_RS14575 () | 103751..103996 | + | 246 | WP_002323040.1 | hypothetical protein | - |
| EL354_RS14580 () | 103993..104490 | - | 498 | WP_002316138.1 | Spermidine/spermine N(1)-acetyltransferase | VF |
| EL354_RS14585 () | 104546..105454 | - | 909 | WP_079504102.1 | IS982 family transposase ISEfm1 | Transposase |
| EL354_RS14595 () | 106215..107410 | + | 1196 | Protein_105 | IS256 family transposase IS16 | Transposase |
| EL354_RS14600 () | 107743..108423 | - | 681 | WP_085803942.1 | IS6 family transposase ISS1W | Transposase |
| EL354_RS14605 () | 108461..109786 | - | 1326 | WP_002347212.1 | cation transporter | - |
| EL354_RS14610 () | 109814..110425 | - | 612 | WP_002322692.1 | CadD family cadmium resistance transporter | - |
| EL354_RS14615 () | 110442..110807 | - | 366 | WP_002330544.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| EL354_RS14620 () | 111163..113067 | - | 1905 | WP_002322690.1 | heavy metal translocating P-type ATPase | - |
| EL354_RS14625 () | 113265..113498 | - | 234 | WP_002301447.1 | cation transporter | - |
| EL354_RS14630 () | 113645..114499 | - | 855 | WP_002322689.1 | prolipoprotein diacylglyceryl transferase | - |
| EL354_RS14635 () | 114484..114822 | - | 339 | WP_002300938.1 | hypothetical protein | - |
| EL354_RS14640 () | 115050..115754 | - | 705 | WP_002292156.1 | Crp/Fnr family transcriptional regulator | - |
| EL354_RS14645 () | 115899..116471 | - | 573 | WP_002292150.1 | DNA protection during starvation protein | VF |
| EL354_RS14655 () | 117026..118198 | + | 1173 | WP_002323279.1 | IS256 family transposase IS256 | Transposase |
| EL354_RS14660 () | 118352..118882 | - | 531 | Protein_117 | IS982 family transposase ISEfm1 | Transposase |
| EL354_RS14665 () | 118954..120246 | + | 1293 | WP_002298232.1 | ISL3 family transposase IS1251 | Transposase |
| EL354_RS14670 () | 120458..121300 | - | 843 | WP_002289586.1 | PRD domain-containing protein | - |
| EL354_RS14675 () | 121337..122803 | - | 1467 | WP_002289584.1 | glycoside hydrolase family 1 protein | - |
| EL354_RS14680 () | 122859..124703 | - | 1845 | WP_002298230.1 | beta-glucoside-specific PTS transporter subunit IIABC | - |
| EL354_RS14685 () | 125305..126255 | + | 951 | WP_002300609.1 | Transcriptional regulatory protein DagR | VF |
| EL354_RS14690 () | 126300..126933 | - | 634 | Protein_123 | peptidase | - |
| EL354_RS14695 () | 127193..127741 | - | 549 | WP_002292681.1 | hypothetical protein | - |
| EL354_RS14700 () | 127742..128599 | - | 858 | WP_002292680.1 | AAA family ATPase | - |
| EL354_RS14705 () | 128772..129950 | - | 1179 | WP_002324322.1 | IS256 family transposase ISEfm2 | Transposase |
| EL354_RS14710 () | 130218..130505 | - | 288 | WP_002300557.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| EL354_RS14715 () | 130495..130824 | - | 330 | WP_002292678.1 | AbrB family transcriptional regulator | - |
| EL354_RS14720 () | 130901..131173 | - | 273 | WP_002314366.1 | Txe/YoeB family addiction module toxin | Toxin Detail |
| EL354_RS14725 () | 131173..131436 | - | 264 | WP_002297422.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| EL354_RS14730 () | 131670..132578 | + | 909 | WP_002295743.1 | IS982 family transposase ISEfm1 | Transposase |
| EL354_RS14735 () | 132581..133756 | - | 1176 | WP_002323312.1 | MFS transporter | - |
| EL354_RS14740 () | 133759..136008 | - | 2250 | WP_002323313.1 | alpha-galactosidase | - |
| EL354_RS14745 () | 136105..136959 | - | 855 | WP_002323314.1 | AraC family transcriptional regulator | - |
| EL354_RS14750 () | 137046..137954 | - | 909 | WP_002295743.1 | IS982 family transposase ISEfm1 | Transposase |
| EL354_RS14755 () | 138048..138983 | - | 936 | WP_002323400.1 | hypothetical protein | - |
| EL354_RS14760 () | 139542..139859 | - | 318 | WP_002290394.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| EL354_RS14765 () | 139860..140114 | - | 255 | WP_002323399.1 | hypothetical protein | - |
| EL354_RS14770 () | 140473..140877 | + | 405 | WP_002287522.1 | IS200-IS605 family transposase ISEfa4 | Transposase |
| EL354_RS14775 () | 140894..142042 | + | 1149 | WP_002287525.1 | IS200-IS605 family transposase ISEfa4 | Transposase |
| EL354_RS14780 () | 142265..142483 | - | 219 | Protein_141 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| EL354_RS14785 () | 142749..142943 | - | 195 | WP_002348857.1 | hypothetical protein | - |
| EL354_RS14790 () | 143043..143129 | - | 87 | Protein_143 | single-stranded DNA-binding protein | - |
| EL354_RS14795 () | 143622..144575 | + | 954 | WP_002325884.1 | IS30 family transposase IS1252 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|