MGE detailed information
MGE type: Conjugative plasmid MGE length: 93927 bp
Accession: NZ_LR130554 Location: 1..93927 Organism: Escherichia coli strain MS14386 isolate MS14386 Replicon: plasmid 3
Accession: NZ_LR130554 Location: 1..93927 Organism: Escherichia coli strain MS14386 isolate MS14386 Replicon: plasmid 3
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EW035_RS24175 () | 1..858 | + | 858 | WP_000130647.1 | incFII family plasmid replication initiator RepA | - |
| EW035_RS24190 () | 1952..2344 | - | 393 | Protein_1 | hypothetical protein | VF |
| EW035_RS24195 () | 2377..5409 | - | 3033 | WP_039022048.1 | Tn3 family transposase ISPsy42 | Transposase |
| EW035_RS24200 () | 5413..5973 | - | 561 | WP_039022047.1 | Tn3 family transposase TnpR_TnAs2 | Transposase |
| EW035_RS24205 () | 6104..6454 | - | 351 | WP_000454193.1 | DUF3330 domain-containing protein | - |
| EW035_RS24215 () | 6657..7669 | - | 1013 | Protein_5 | IS91 family transposase ISAzo26 | Transposase |
| EW035_RS24220 () | 7814..8311 | + | 498 | WP_001083725.1 | Dihydrofolate reductase | ARG |
| EW035_RS24230 () | 8489..9253 | + | 765 | WP_001389365.1 | IS6 family transposase IS6100 | Transposase |
| EW035_RS24245 () | 9746..10330 | - | 585 | WP_001137892.1 | TetR family transcriptional regulator | - |
| EW035_RS24250 () | 10330..11568 | - | 1239 | WP_000004159.1 | MFS transporter | - |
| EW035_RS24255 () | 11565..12470 | - | 906 | WP_000219391.1 | hypothetical protein | ARG |
| EW035_RS24265 () | 12592..13296 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| EW035_RS24270 () | 13682..14098 | + | 417 | WP_034169466.1 | Glutathione transferase FosA | ARG |
| EW035_RS24275 () | 14103..14621 | - | 519 | WP_034169467.1 | hypothetical protein | - |
| EW035_RS24280 () | 14621..15292 | - | 672 | Protein_14 | winged helix-turn-helix domain-containing protein | - |
| EW035_RS24285 () | 15346..16050 | - | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| EW035_RS24290 () | 16159..16353 | + | 195 | Protein_16 | replication initiation protein | - |
| EW035_RS24295 () | 16361..16810 | + | 450 | WP_023281052.1 | hypothetical protein | - |
| EW035_RS25010 () | 16789..16938 | + | 150 | WP_152930637.1 | hypothetical protein | - |
| EW035_RS24300 () | 17458..17997 | + | 540 | WP_039021305.1 | hypothetical protein | - |
| EW035_RS24305 () | 18008..18457 | + | 450 | WP_039021304.1 | hypothetical protein | - |
| EW035_RS24310 () | 18441..18983 | + | 543 | WP_039021303.1 | hypothetical protein | - |
| EW035_RS24315 () | 19055..19462 | + | 408 | WP_001567331.1 | hypothetical protein | - |
| EW035_RS24320 () | 19505..19708 | + | 204 | WP_001567330.1 | hypothetical protein | - |
| EW035_RS24325 () | 19957..22005 | + | 2049 | WP_023281053.1 | site-specific DNA-methyltransferase | - |
| EW035_RS24330 () | 22010..24646 | + | 2637 | WP_023281054.1 | DEAD/DEAH box helicase family protein | - |
| EW035_RS24335 () | 24689..24781 | - | 93 | Protein_26 | tRNA modification GTPase | - |
| EW035_RS24340 () | 24930..25790 | - | 861 | WP_050190632.1 | Beta-lactamase TEM | ARG |
| EW035_RS24345 () | 25925..26629 | - | 705 | WP_001067858.1 | IS6 family transposase IS15DI | Transposase |
| EW035_RS24355 () | 27443..27691 | + | 249 | Protein_29 | IS1380 family transposase ISEcp1 | Transposase |
| EW035_RS24360 () | 27811..28152 | + | 342 | WP_004202492.1 | Multiple antibiotic resistance protein MarA | VF |
| EW035_RS24365 () | 28383..28679 | - | 297 | Protein_31 | IS6 family transposase IS15DII | Transposase |
| EW035_RS24370 () | 28710..28919 | - | 210 | Protein_32 | IS6 family transposase IS15DII | Transposase |
| EW035_RS24375 () | 28985..30499 | + | 1515 | Protein_33 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| EW035_RS24380 () | 30568..31452 | + | 885 | WP_001345827.1 | hypothetical protein | - |
| EW035_RS24385 () | 31448..31617 | + | 170 | Protein_35 | resolvase | - |
| EW035_RS25015 () | 31624..31791 | - | 168 | WP_001430249.1 | hypothetical protein | - |
| EW035_RS24395 () | 31963..34638 | - | 2676 | WP_015059139.1 | hypothetical protein | - |
| EW035_RS24400 () | 34941..35942 | + | 1002 | WP_000138753.1 | DUF4238 domain-containing protein | - |
| EW035_RS24405 () | 36167..36629 | - | 463 | Protein_39 | hypothetical protein | - |
| EW035_RS24410 () | 36738..37088 | - | 351 | WP_001430247.1 | plasmid partitioning/stability family protein | - |
| EW035_RS24415 () | 37091..38053 | - | 963 | WP_000959875.1 | plasmid segregation protein ParM | - |
| EW035_RS24420 () | 38185..38493 | + | 309 | WP_039021875.1 | hypothetical protein | - |
| EW035_RS24430 () | 38570..39253 | + | 684 | WP_000085889.1 | DNA methylase | - |
| EW035_RS24435 () | 39254..39475 | + | 222 | WP_001104902.1 | hypothetical protein | - |
| EW035_RS24440 () | 39488..39922 | + | 435 | WP_000274504.1 | DUF1380 family protein | - |
| EW035_RS25065 () | 39967..40738 | + | 772 | Protein_46 | hypothetical protein | - |
| EW035_RS24455 () | 41221..41523 | + | 303 | WP_001671341.1 | antirestriction protein | - |
| EW035_RS24460 () | 41570..41992 | + | 423 | WP_000271684.1 | DUF1380 family protein | - |
| EW035_RS24465 () | 41989..42180 | + | 192 | WP_039021874.1 | hypothetical protein | - |
| EW035_RS24475 () | 43215..43445 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| EW035_RS24480 () | 43497..44858 | + | 1362 | WP_000170715.1 | DUF3560 domain-containing protein | - |
| EW035_RS24485 () | 44906..45469 | + | 564 | WP_001315564.1 | class I SAM-dependent methyltransferase | - |
| EW035_RS24490 () | 45495..45734 | + | 240 | WP_094326110.1 | hypothetical protein | - |
| EW035_RS24505 () | 46145..46351 | + | 207 | WP_000275858.1 | hypothetical protein | - |
| EW035_RS24510 () | 46377..46916 | + | 540 | WP_001825195.1 | single-stranded DNA-binding protein | - |
| EW035_RS24515 () | 46979..47212 | + | 234 | WP_000005990.1 | DUF905 family protein | - |
| EW035_RS24520 () | 47278..49236 | + | 1959 | WP_001825193.1 | ParB/RepB/Spo0J family partition protein | - |
| EW035_RS24525 () | 49291..49725 | + | 435 | WP_000845953.1 | conjugation system SOS inhibitor PsiB | - |
| EW035_RS24530 () | 49722..50441 | + | 720 | WP_013362833.1 | plasmid SOS inhibition protein A | - |
| EW035_RS25020 () | 50453..50641 | - | 189 | WP_001299721.1 | hypothetical protein | - |
| - () | 50453..50677 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 50453..50677 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 50453..50677 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 50453..50677 | + | 225 | NuclAT_0 | - | Antitoxin Detail |
| - () | 50610..50675 | - | 66 | - | - | Antitoxin Detail |
| EW035_RS24535 () | 50721..50879 | + | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| EW035_RS24555 () | 51801..52088 | + | 288 | WP_000107544.1 | hypothetical protein | - |
| EW035_RS24560 () | 52209..53030 | + | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| EW035_RS24565 () | 53327..53974 | - | 648 | WP_031943493.1 | hypothetical protein | VF |
| EW035_RS24570 () | 54251..54634 | + | 384 | WP_000124981.1 | relaxosome protein TraM | - |
| EW035_RS24575 () | 54825..55511 | + | 687 | WP_000332484.1 | PAS domain-containing protein | - |
| EW035_RS24580 () | 55605..55832 | + | 228 | WP_001254386.1 | conjugal transfer relaxosome protein TraY | - |
| EW035_RS24585 () | 55866..56228 | + | 363 | WP_000340279.1 | type IV conjugative transfer system pilin TraA | - |
| EW035_RS24590 () | 56233..56544 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| EW035_RS24595 () | 56566..57132 | + | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| EW035_RS24600 () | 57143..57847 | + | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| EW035_RS24605 () | 57847..59274 | + | 1428 | WP_000146655.1 | conjugal transfer protein TraB | - |
| EW035_RS24610 () | 59264..59836 | + | 573 | WP_000002780.1 | conjugal transfer protein TraP | - |
| EW035_RS24615 () | 59833..60150 | + | 318 | WP_001057292.1 | conjugal transfer protein TrbD | - |
| EW035_RS24620 () | 60147..60398 | + | 252 | WP_001038341.1 | conjugal transfer protein TrbG | - |
| EW035_RS24625 () | 60395..60910 | + | 516 | WP_039021963.1 | type IV conjugative transfer system lipoprotein TraV | - |
| EW035_RS24630 () | 61045..61266 | + | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| EW035_RS24635 () | 61426..64053 | + | 2628 | WP_039021964.1 | type IV secretion system protein TraC | - |
| EW035_RS24640 () | 64050..64436 | + | 387 | WP_000214096.1 | type-F conjugative transfer system protein TrbI | - |
| EW035_RS24645 () | 64433..65065 | + | 633 | WP_001203745.1 | type-F conjugative transfer system protein TraW | - |
| EW035_RS24650 () | 65062..66054 | + | 993 | WP_000830839.1 | conjugal transfer pilus assembly protein TraU | - |
| EW035_RS24655 () | 66080..66541 | + | 462 | WP_000277845.1 | hypothetical protein | - |
| EW035_RS24660 () | 66571..67023 | + | 453 | WP_039021965.1 | hypothetical protein | - |
| EW035_RS24665 () | 67051..67689 | + | 639 | WP_129753567.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| EW035_RS24670 () | 67686..69494 | + | 1809 | WP_000821818.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| EW035_RS24675 () | 69521..69778 | + | 258 | WP_000864325.1 | conjugal transfer protein TrbE | - |
| EW035_RS24680 () | 69771..70514 | + | 744 | WP_001030376.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| EW035_RS24685 () | 70530..70877 | + | 348 | WP_001287902.1 | conjugal transfer protein TrbA | - |
| EW035_RS24690 () | 70996..71280 | + | 285 | WP_000624110.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| EW035_RS24695 () | 71267..71812 | + | 546 | WP_039021966.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| EW035_RS24700 () | 71742..72104 | + | 363 | WP_001443292.1 | P-type conjugative transfer protein TrbJ | - |
| EW035_RS24705 () | 72104..73477 | + | 1374 | WP_001137358.1 | conjugal transfer protein TraH | - |
| EW035_RS24710 () | 73474..76299 | + | 2826 | WP_001007045.1 | conjugal transfer mating pair stabilization protein TraG | - |
| EW035_RS24715 () | 76296..76805 | + | 510 | WP_031943494.1 | conjugal transfer entry exclusion protein TraS | - |
| EW035_RS24720 () | 76819..77550 | + | 732 | WP_000850424.1 | complement resistance protein TraT | - |
| EW035_RS24730 () | 77842..78519 | + | 678 | WP_001682408.1 | IS66 family transposase ISCro1 | Transposase |
| EW035_RS24735 () | 78519..78866 | + | 348 | WP_000624622.1 | IS66 family transposase ISCro1 | Transposase |
| EW035_RS24740 () | 78886..80457 | + | 1572 | WP_000381395.1 | IS66 family transposase ISCro1 | Transposase |
| EW035_RS24745 () | 80510..82717 | + | 2208 | WP_000009364.1 | type IV conjugative transfer system coupling protein TraD | - |
| EW035_RS24750 () | 82717..87987 | + | 5271 | WP_039021708.1 | Multifunctional conjugation protein TraI | Relaxase |
| EW035_RS24755 () | 88007..88753 | + | 747 | WP_015059122.1 | conjugal transfer pilus acetylase TraX | - |
| EW035_RS24760 () | 88808..89368 | + | 561 | WP_000139341.1 | fertility inhibition protein FinO | - |
| EW035_RS24770 () | 89998..90675 | + | 678 | WP_000392235.1 | hypothetical protein | - |
| EW035_RS24775 () | 91329..91541 | + | 213 | Protein_104 | ANR family transcriptional regulator | - |
| EW035_RS24785 () | 91785..92246 | + | 462 | WP_015059120.1 | thermonuclease family protein | - |
| EW035_RS24790 () | 92292..92501 | + | 210 | WP_001333231.1 | hemolysin expression modulator Hha | - |
| EW035_RS24795 () | 92539..93129 | + | 591 | WP_000766816.1 | DUF2726 domain-containing protein | - |
| EW035_RS24800 () | 93369..93623 | + | 255 | WP_000083830.1 | replication regulatory protein RepA | - |
| EW035_RS24810 () | 93861..93927 | + | 67 | WP_032190884.1 | RepA leader peptide Tap | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|