MGE detailed information
MGE type: Conjugative plasmid MGE length: 121788 bp
Accession: NZ_CP126956 Location: 1..121788 Organism: Escherichia coli O78:H4 strain APEC E123 Replicon: plasmid pEND_Eco 123-1
Accession: NZ_CP126956 Location: 1..121788 Organism: Escherichia coli O78:H4 strain APEC E123 Replicon: plasmid pEND_Eco 123-1
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QQA21_RS24530 (223) | 223..420 | - | 198 | WP_001324648.1 | conjugal transfer protein TrbD | - |
| QQA21_RS24535 (407) | 407..862 | - | 456 | WP_289245781.1 | conjugal transfer pilus-stabilizing protein TraP | - |
| QQA21_RS24540 (794) | 794..3595 | + | 2802 | WP_289245780.1 | conjugal transfer mating-pair stabilization protein TraG | - |
| QQA21_RS24545 (3611) | 3611..4108 | + | 498 | WP_000605857.1 | entry exclusion protein | - |
| QQA21_RS24550 (4140) | 4140..4871 | + | 732 | WP_023565183.1 | conjugal transfer complement resistance protein TraT | - |
| QQA21_RS24555 (5147) | 5147..5824 | + | 678 | WP_001682408.1 | IS66 family transposase ISCro1 | Transposase |
| QQA21_RS24560 (5824) | 5824..6171 | + | 348 | WP_000624622.1 | IS66 family transposase ISCro1 | Transposase |
| QQA21_RS24565 (6191) | 6191..7762 | + | 1572 | WP_000381395.1 | IS66 family transposase ISCro1 | Transposase |
| QQA21_RS24570 (7831) | 7831..9984 | + | 2154 | WP_000009324.1 | type IV conjugative transfer system coupling protein TraD | - |
| QQA21_RS24575 (9993) | 9993..10391 | - | 399 | WP_000911313.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| QQA21_RS24580 (10391) | 10391..10618 | - | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| QQA21_RS24585 (10700) | 10700..14590 | + | 3891 | WP_116838173.1 | hypothetical protein | Relaxase |
| QQA21_RS24590 (14610) | 14610..15356 | + | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| QQA21_RS24595 (15415) | 15415..16275 | + | 861 | WP_000704513.1 | Quorum-quenching protein AidA | VF |
| QQA21_RS24600 (16378) | 16378..16938 | + | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| QQA21_RS24605 (17074) | 17074..17286 | + | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| QQA21_RS24610 (17532) | 17532..17606 | + | 75 | Protein_17 | endonuclease | - |
| - (17862) | 17862..17923 | - | 62 | NuclAT_1 | - | - |
| - (17862) | 17862..17923 | - | 62 | NuclAT_1 | - | - |
| - (17862) | 17862..17923 | - | 62 | NuclAT_1 | - | - |
| - (17862) | 17862..17923 | - | 62 | NuclAT_1 | - | - |
| QQA21_RS24615 (17967) | 17967..18116 | + | 150 | WP_001312851.1 | Hok/Gef family protein | Toxin Detail |
| QQA21_RS24620 (18400) | 18400..18657 | + | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| QQA21_RS24625 (18674) | 18674..18925 | - | 252 | WP_223195197.1 | replication protein RepA | - |
| QQA21_RS24630 (18916) | 18916..18963 | + | 48 | WP_229471593.1 | hypothetical protein | - |
| QQA21_RS24635 (18956) | 18956..19438 | + | 483 | WP_001273588.1 | hypothetical protein | - |
| QQA21_RS24640 (19431) | 19431..20288 | + | 858 | WP_000774297.1 | incFII family plasmid replication initiator RepA | - |
| QQA21_RS24645 (21224) | 21224..21568 | + | 345 | WP_001553768.1 | hypothetical protein | - |
| QQA21_RS24650 (21749) | 21749..22864 | - | 1116 | Protein_25 | IS91 family transposase IS91 | Transposase |
| QQA21_RS24655 (22864) | 22864..23229 | - | 366 | WP_000124098.1 | hypothetical protein | - |
| QQA21_RS24660 (23486) | 23486..24508 | + | 1023 | WP_000255944.1 | IS21 family transposase IS100kyp | Transposase |
| QQA21_RS24665 (24505) | 24505..25287 | + | 783 | WP_001300609.1 | IS21 family transposase IS100kyp | Transposase |
| QQA21_RS24670 (25331) | 25331..26461 | - | 1131 | WP_069024894.1 | IS30 family transposase IS30D | Transposase |
| QQA21_RS24675 (26529) | 26529..26786 | - | 258 | Protein_30 | IS3 family transposase IS911 | Transposase |
| QQA21_RS24680 (27065) | 27065..27256 | - | 192 | Protein_31 | IS91 family transposase | - |
| QQA21_RS24685 (27427) | 27427..31560 | + | 4134 | WP_001080137.1 | Temperature-sensitive hemagglutinin tsh autotransporter | VF |
| QQA21_RS24690 (31669) | 31669..32061 | + | 393 | Protein_33 | peptide deformylase | - |
| QQA21_RS24695 (32108) | 32108..32374 | - | 267 | Protein_34 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| QQA21_RS24700 (32414) | 32414..33951 | - | 1538 | Protein_35 | IS66 family transposase ISEc8 | Transposase |
| QQA21_RS24705 (34001) | 34001..34348 | - | 348 | WP_000612591.1 | IS66 family transposase ISEc8 | Transposase |
| QQA21_RS24710 (34345) | 34345..34725 | - | 381 | WP_001171523.1 | IS66 family transposase ISEc8 | Transposase |
| QQA21_RS24715 (34801) | 34801..35781 | - | 981 | WP_001017346.1 | NAD(P)-binding domain-containing protein | - |
| QQA21_RS24720 (35778) | 35778..36047 | - | 270 | WP_000379710.1 | SemiSWEET transporter | - |
| QQA21_RS24725 (36049) | 36049..36453 | - | 405 | WP_001389361.1 | hypothetical protein | - |
| QQA21_RS24730 (36425) | 36425..36868 | - | 444 | WP_001323891.1 | dehydrogenase | - |
| QQA21_RS24735 (36987) | 36987..37223 | + | 237 | WP_001323890.1 | colicin V immunity protein | - |
| QQA21_RS24740 (37201) | 37201..37512 | + | 312 | WP_001259758.1 | colicin V | - |
| QQA21_RS24745 (37682) | 37682..39778 | - | 2097 | WP_000184924.1 | microcin H47 export transporter peptidase/ATP-binding subunit MchF | - |
| QQA21_RS24750 (39771) | 39771..41045 | - | 1275 | WP_000489609.1 | HlyD family secretion protein | - |
| QQA21_RS24755 (41671) | 41671..41924 | + | 254 | Protein_46 | type II toxin-antitoxin system antitoxin YacA | - |
| QQA21_RS24760 (41924) | 41924..42049 | + | 126 | Protein_47 | type II toxin-antitoxin system toxin YacB | - |
| QQA21_RS24765 (42202) | 42202..42510 | + | 309 | WP_000377483.1 | DUF6404 family protein | - |
| QQA21_RS24770 (42588) | 42588..42889 | - | 302 | Protein_49 | hypothetical protein | - |
| QQA21_RS24775 (43070) | 43070..44104 | + | 1035 | WP_001190234.1 | 3-deoxy-7-phosphoheptulonate synthase | - |
| QQA21_RS24780 (44970) | 44970..47147 | + | 2178 | WP_001222186.1 | Ferric enterobactin receptor | VF |
| QQA21_RS24785 (47192) | 47192..48148 | - | 957 | WP_000271274.1 | hypothetical protein | VF |
| QQA21_RS24790 (48233) | 48233..49462 | - | 1230 | WP_000933678.1 | Enterochelin esterase | VF |
| QQA21_RS24795 (49566) | 49566..53225 | - | 3660 | WP_001389363.1 | Multidrug efflux ATP-binding/permease protein | VF |
| QQA21_RS24800 (53365) | 53365..54480 | - | 1116 | WP_001318220.1 | Elloramycin glycosyltransferase ElmGT | VF |
| QQA21_RS24805 (55791) | 55791..56815 | - | 1025 | Protein_56 | integrase core domain-containing protein | - |
| QQA21_RS24810 (57369) | 57369..57568 | + | 200 | Protein_57 | lysis protein | - |
| QQA21_RS24815 (57626) | 57626..57919 | - | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| QQA21_RS24820 (58544) | 58544..59064 | + | 521 | Protein_59 | IS3 family transposase IS2 | Transposase |
| QQA21_RS24830 (60296) | 60296..61033 | + | 738 | Protein_61 | IS3 family transposase IS2 | Transposase |
| QQA21_RS24835 (62275) | 62275..63468 | + | 1194 | WP_000450494.1 | GTP-binding protein | - |
| QQA21_RS24840 (63646) | 63646..63795 | + | 150 | Protein_63 | IS3 family transposase IS2 | Transposase |
| QQA21_RS24845 (64105) | 64105..65494 | + | 1390 | Protein_64 | ISNCY family transposase ISKpn21 | Transposase |
| QQA21_RS24850 (65729) | 65729..66670 | + | 942 | WP_000974762.1 | hypothetical protein | - |
| QQA21_RS24855 (66799) | 66799..66993 | - | 195 | Protein_66 | IS200/IS605-like element IS200C family transposase | - |
| QQA21_RS24860 (67467) | 67467..68837 | - | 1371 | WP_001312828.1 | efflux transporter outer membrane subunit | - |
| QQA21_RS24865 (68841) | 68841..70781 | - | 1941 | WP_000733250.1 | Macrolide export ATP-binding/permease protein MacB | VF |
| QQA21_RS24870 (70778) | 70778..71965 | - | 1188 | WP_000928804.1 | efflux RND transporter periplasmic adaptor subunit | - |
| QQA21_RS24875 (72560) | 72560..72900 | - | 341 | Protein_70 | IS3 family transposase | - |
| QQA21_RS24880 (72946) | 72946..73271 | + | 326 | Protein_71 | IS3 family transposase IS911 | Transposase |
| QQA21_RS24885 (73419) | 73419..74618 | - | 1200 | Protein_72 | IS3 family transposase IS629 | Transposase |
| QQA21_RS24890 (74757) | 74757..74936 | + | 180 | Protein_73 | integrase core domain-containing protein | - |
| QQA21_RS24895 (76233) | 76233..77186 | + | 954 | WP_000280980.1 | Protease 7 | VF |
| QQA21_RS24900 (77619) | 77619..78728 | + | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| QQA21_RS24905 (78797) | 78797..79699 | + | 903 | WP_001312822.1 | hypothetical protein | VF |
| QQA21_RS24910 (80073) | 80073..80261 | + | 189 | WP_001324033.1 | hypothetical protein | - |
| QQA21_RS24915 (80382) | 80382..81122 | + | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| QQA21_RS24920 (81407) | 81407..82384 | - | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| QQA21_RS24925 (82660) | 82660..82941 | + | 282 | WP_182110967.1 | hypothetical protein | - |
| QQA21_RS24930 (83137) | 83137..83460 | + | 324 | Protein_81 | IS21 family transposase IS21 | Transposase |
| QQA21_RS24935 (83462) | 83462..83566 | + | 105 | Protein_82 | AAA family ATPase | - |
| QQA21_RS24940 (83627) | 83627..84140 | + | 514 | Protein_83 | DUF4113 domain-containing protein | - |
| QQA21_RS24950 (85373) | 85373..86287 | + | 915 | WP_000949004.1 | putative periplasmic iron-binding protein | VF |
| QQA21_RS24955 (86287) | 86287..87114 | + | 828 | WP_000983710.1 | Manganese transport system ATP-binding protein MntB | VF |
| QQA21_RS24960 (87111) | 87111..87968 | + | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| QQA21_RS24965 (87965) | 87965..88822 | + | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| QQA21_RS24970 (89056) | 89056..89313 | - | 258 | Protein_89 | Tn3 family transposase | - |
| QQA21_RS24975 (89311) | 89311..89724 | + | 414 | Protein_90 | phosphopyruvate hydratase | - |
| QQA21_RS24980 (90065) | 90065..90445 | + | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| QQA21_RS24985 (90825) | 90825..92018 | - | 1194 | WP_000095526.1 | MFS transporter | - |
| QQA21_RS24990 (92154) | 92154..93878 | + | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| QQA21_RS24995 (93879) | 93879..94826 | + | 948 | WP_000011910.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| QQA21_RS25000 (94826) | 94826..96568 | + | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| QQA21_RS25005 (96565) | 96565..97898 | + | 1334 | Protein_96 | L-lysine N6-monooxygenase | VF |
| QQA21_RS25010 (97924) | 97924..100125 | + | 2202 | WP_000973520.1 | Ferric aerobactin receptor | VF |
| QQA21_RS25015 (100610) | 100610..101307 | + | 698 | WP_223155668.1 | IS1 family transposase IS1S | Transposase |
| QQA21_RS25020 (101607) | 101607..102773 | + | 1167 | WP_001238646.1 | hypothetical protein | VF |
| QQA21_RS25025 (102773) | 102773..103744 | + | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| QQA21_RS25030 (104338) | 104338..104507 | + | 170 | Protein_101 | hypothetical protein | - |
| QQA21_RS25035 (104690) | 104690..104770 | - | 81 | Protein_102 | hypothetical protein | - |
| QQA21_RS25040 (104840) | 104840..105046 | + | 207 | WP_000275856.1 | hypothetical protein | - |
| QQA21_RS25045 (105072) | 105072..105611 | + | 540 | WP_000290840.1 | single-stranded DNA-binding protein | - |
| QQA21_RS25050 (105679) | 105679..105912 | + | 234 | WP_000005990.1 | DUF905 family protein | - |
| QQA21_RS25055 (105940) | 105940..106137 | + | 198 | Protein_106 | hypothetical protein | - |
| QQA21_RS25060 (106192) | 106192..106626 | + | 435 | WP_000845936.1 | conjugation system SOS inhibitor PsiB | - |
| QQA21_RS25065 (106623) | 106623..107385 | + | 763 | Protein_108 | plasmid SOS inhibition protein A | - |
| QQA21_RS25070 (107354) | 107354..107542 | - | 189 | WP_001299721.1 | hypothetical protein | - |
| - (107354) | 107354..107578 | + | 225 | NuclAT_0 | - | - |
| - (107354) | 107354..107578 | + | 225 | NuclAT_0 | - | - |
| - (107354) | 107354..107578 | + | 225 | NuclAT_0 | - | - |
| - (107354) | 107354..107578 | + | 225 | NuclAT_0 | - | - |
| QQA21_RS25075 (107564) | 107564..107713 | + | 150 | Protein_110 | plasmid maintenance protein Mok | - |
| QQA21_RS25080 (107655) | 107655..107780 | + | 126 | WP_001372321.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| QQA21_RS25085 (108000) | 108000..108230 | + | 231 | WP_071586998.1 | hypothetical protein | - |
| QQA21_RS25090 (108228) | 108228..108400 | - | 173 | Protein_113 | hypothetical protein | - |
| QQA21_RS25095 (108470) | 108470..108676 | + | 207 | WP_000547968.1 | hypothetical protein | - |
| QQA21_RS25100 (108701) | 108701..108988 | + | 288 | WP_000107535.1 | hypothetical protein | - |
| QQA21_RS25105 (109106) | 109106..109927 | + | 822 | WP_001234426.1 | DUF932 domain-containing protein | - |
| QQA21_RS25110 (110224) | 110224..110814 | - | 591 | WP_289245779.1 | hypothetical protein | VF |
| QQA21_RS25115 (111147) | 111147..111530 | + | 384 | WP_001151524.1 | conjugal transfer relaxosome DNA-binding protein TraM | - |
| QQA21_RS25120 (111717) | 111717..112406 | + | 690 | WP_015918718.1 | conjugal transfer transcriptional regulator TraJ | - |
| QQA21_RS25125 (112499) | 112499..112900 | + | 402 | WP_001369361.1 | conjugal transfer relaxosome DNA-bindin protein TraY | - |
| QQA21_RS25130 (112933) | 112933..113298 | + | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| QQA21_RS25135 (113313) | 113313..113624 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| QQA21_RS25140 (113646) | 113646..114212 | + | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| QQA21_RS25145 (114199) | 114199..114834 | + | 636 | Protein_124 | type-F conjugative transfer system secretin TraK | - |
| QQA21_RS25150 (114834) | 114834..116072 | - | 1239 | Protein_125 | conjugal transfer pilus assembly protein TraH | - |
| QQA21_RS25155 (116072) | 116072..116452 | - | 381 | WP_001389370.1 | F-type conjugal transfer protein TrbF | - |
| QQA21_RS25160 (116439) | 116439..116780 | - | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| QQA21_RS25165 (116710) | 116710..117255 | - | 546 | WP_000059851.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| QQA21_RS25170 (117242) | 117242..117526 | - | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| QQA21_RS25175 (117607) | 117607..117921 | + | 315 | WP_001324103.1 | hypothetical protein | - |
| QQA21_RS25180 (117923) | 117923..118270 | - | 348 | WP_001287679.1 | conjugal transfer protein TrbA | - |
| QQA21_RS25185 (118286) | 118286..119029 | - | 744 | WP_001030378.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| QQA21_RS25190 (119022) | 119022..119279 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| QQA21_RS25195 (119306) | 119306..120106 | - | 801 | Protein_134 | conjugal transfer protein TraN | - |
| QQA21_RS25200 (120106) | 120106..120720 | - | 615 | Protein_135 | TraC family protein | - |
| QQA21_RS25205 (120880) | 120880..121101 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| QQA21_RS25210 (121236) | 121236..121751 | - | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|